Format

Send to:

Choose Destination

Dusp5 dual specificity phosphatase 5 [ Mus musculus (house mouse) ]

Gene ID: 240672, updated on 8-May-2016
Official Symbol
Dusp5provided by MGI
Official Full Name
dual specificity phosphatase 5provided by MGI
Primary source
MGI:MGI:2685183
See related
Ensembl:ENSMUSG00000034765
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm337
Orthologs
Location:
19; 19 D2
Exon count:
4
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 19 NC_000085.6 (53529318..53541322)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (53603808..53615812)

Chromosome 19 - NC_000085.6Genomic Context describing neighboring genes Neighboring gene myocardial infarction associated transcript 1 Neighboring gene uncharacterized LOC73899 Neighboring gene predicted gene, 30826 Neighboring gene nuclear transport factor 2, pseudogene 1 Neighboring gene structural maintenance of chromosomes 3

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
MAP kinase tyrosine/serine/threonine phosphatase activity ISO
Inferred from Sequence Orthology
more info
 
phosphoprotein phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
protein tyrosine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
endoderm formation IBA
Inferred from Biological aspect of Ancestor
more info
 
inactivation of MAPK activity ISO
Inferred from Sequence Orthology
more info
 
negative regulation of transcription, DNA-templated ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
dual specificity protein phosphatase 5
NP_001078859.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001085390.1NP_001078859.1  dual specificity protein phosphatase 5

    See identical proteins and their annotated locations for NP_001078859.1

    Status: PROVISIONAL

    Source sequence(s)
    DQ479917
    Consensus CDS
    CCDS38024.1
    UniProtKB/TrEMBL
    Q1HL35
    Related
    ENSMUSP00000047900, OTTMUSP00000038291, ENSMUST00000038287, OTTMUST00000073872
    Conserved Domains (3) summary
    COG2453
    Location:227318
    CDC14; Protein-tyrosine phosphatase [Signal transduction mechanisms]
    cd00127
    Location:178314
    DSPc; Dual specificity phosphatases (DSP); Ser/Thr and Tyr protein phosphatases. Structurally similar to tyrosine-specific phosphatases but with a shallower active site cleft and a distinctive active site signature motif, HCxxGxxR. Characterized as VHR- or ...
    cd01446
    Location:5140
    DSP_MapKP; N-terminal regulatory rhodanese domain of dual specificity phosphatases (DSP), such as Mapk Phosphatase. This domain is believed to determine substrate specificity by binding the substrate, such as ERK2, and activating the C-terminal catalytic domain by ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000085.6 Reference GRCm38.p3 C57BL/6J

    Range
    53529318..53541322
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000041.1 Alternate Mm_Celera

    Range
    55721417..55733621
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)