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Gtf2h2 general transcription factor II H, polypeptide 2 [ Mus musculus (house mouse) ]

Gene ID: 23894, updated on 21-May-2016
Official Symbol
Gtf2h2provided by MGI
Official Full Name
general transcription factor II H, polypeptide 2provided by MGI
Primary source
MGI:MGI:1345669
See related
Ensembl:ENSMUSG00000021639 Vega:OTTMUSG00000023202
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
p44; 44kDa; Btf2p44; BTF2 p44; BTF2-p44
Location:
13 D1; 13 53.21 cM
Exon count:
19
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 13 NC_000079.6 (100459786..100492610, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (101238532..101262564, complement)

Chromosome 13 - NC_000079.6Genomic Context describing neighboring genes Neighboring gene ubiquitin specific peptidase 38 pseudogene Neighboring gene ribosomal protein L31, pseudogene 13 Neighboring gene NLR family, apoptosis inhibitory protein 1 Neighboring gene occludin Neighboring gene eukaryotic translation initiation factor 4, gamma 1 pseudogene

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
contributes_to DNA-dependent ATPase activity ISO
Inferred from Sequence Orthology
more info
 
contributes_to RNA polymerase II carboxy-terminal domain kinase activity ISO
Inferred from Sequence Orthology
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
protein N-terminus binding ISO
Inferred from Sequence Orthology
more info
 
contributes_to protein kinase activity ISO
Inferred from Sequence Orthology
more info
 
zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
DNA repair IEA
Inferred from Electronic Annotation
more info
 
G-protein coupled receptor internalization ISO
Inferred from Sequence Orthology
more info
 
cellular response to DNA damage stimulus IEA
Inferred from Electronic Annotation
more info
 
nucleotide-excision repair IEA
Inferred from Electronic Annotation
more info
 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
transcription from RNA polymerase II promoter ISO
Inferred from Sequence Orthology
more info
 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
core TFIIH complex IEA
Inferred from Electronic Annotation
more info
 
holo TFIIH complex ISO
Inferred from Sequence Orthology
more info
 
nucleus IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
general transcription factor IIH subunit 2
Names
TFIIH basal transcription factor complex p44 subunit
basal transcription factor 2, p44 subunit
basic transcription factor 2 44 kDa subunit
general transcription factor II H, polypeptide 2 (44 kDa subunit)
general transcription factor IIH, polypeptide 2 (44 kDa subunit)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_022011.4NP_071294.3  general transcription factor IIH subunit 2

    See identical proteins and their annotated locations for NP_071294.3

    Status: VALIDATED

    Source sequence(s)
    BC053382, BY277671, BY480509, DV662169
    Consensus CDS
    CCDS26730.1
    UniProtKB/Swiss-Prot
    Q9JIB4
    UniProtKB/TrEMBL
    Q7TPV0
    Related
    ENSMUSP00000065228, OTTMUSP00000026943, ENSMUST00000066984, OTTMUST00000056139
    Conserved Domains (2) summary
    cd01453
    Location:56236
    vWA_transcription_factor_IIH_type; Transcription factors IIH type: TFIIH is a multiprotein complex that is one of the five general transcription factors that binds RNA polymerase II holoenzyme. Orthologues of these genes are found in all completed eukaryotic genomes and all these proteins ...
    cl06838
    Location:289389
    C1_4; TFIIH C1-like domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000079.6 Reference GRCm38.p3 C57BL/6J

    Range
    100459786..100492610 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006517660.2XP_006517723.1  

    See identical proteins and their annotated locations for XP_006517723.1

    Conserved Domains (2) summary
    cd01453
    Location:56236
    vWA_transcription_factor_IIH_type; Transcription factors IIH type: TFIIH is a multiprotein complex that is one of the five general transcription factors that binds RNA polymerase II holoenzyme. Orthologues of these genes are found in all completed eukaryotic genomes and all these proteins ...
    cl06838
    Location:289389
    C1_4; TFIIH C1-like domain
  2. XM_006517662.2XP_006517725.1  

    See identical proteins and their annotated locations for XP_006517725.1

    Conserved Domains (2) summary
    cd01453
    Location:56236
    vWA_transcription_factor_IIH_type; Transcription factors IIH type: TFIIH is a multiprotein complex that is one of the five general transcription factors that binds RNA polymerase II holoenzyme. Orthologues of these genes are found in all completed eukaryotic genomes and all these proteins ...
    cl06838
    Location:289389
    C1_4; TFIIH C1-like domain

RNA

  1. XR_873756.1 RNA Sequence

  2. XR_873758.1 RNA Sequence

    Related
    ENSMUST00000145266, OTTMUST00000056141
  3. XR_873759.1 RNA Sequence

Alternate Mm_Celera

Genomic

  1. AC_000035.1 Alternate Mm_Celera

    Range
    104083848..104107878 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)