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Fxr2 fragile X mental retardation, autosomal homolog 2 [ Mus musculus (house mouse) ]

Gene ID: 23879, updated on 21-May-2016
Official Symbol
Fxr2provided by MGI
Official Full Name
fragile X mental retardation, autosomal homolog 2provided by MGI
Primary source
MGI:MGI:1346074
See related
Ensembl:ENSMUSG00000018765 Vega:OTTMUSG00000006005
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Fxr2h
Orthologs
Location:
11 B3; 11 42.86 cM
Exon count:
17
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 11 NC_000077.6 (69632971..69653297)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (69446473..69466799)

Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene sex hormone binding globulin Neighboring gene spermidine/spermine N1-acetyl transferase 2 Neighboring gene predicted gene, 32593 Neighboring gene microRNA 467f Neighboring gene SRY (sex determining region Y)-box 15 Neighboring gene mannose-P-dolichol utilization defect 1 Neighboring gene microRNA 1934

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • RNA transport, organism-specific biosystem (from KEGG)
    RNA transport, organism-specific biosystemRNA transport from the nucleus to the cytoplasm is fundamental for gene expression. The different RNA species that are produced in the nucleus are exported through the nuclear pore complexes (NPCs) ...
  • RNA transport, conserved biosystem (from KEGG)
    RNA transport, conserved biosystemRNA transport from the nucleus to the cytoplasm is fundamental for gene expression. The different RNA species that are produced in the nucleus are exported through the nuclear pore complexes (NPCs) ...
  • mRNA processing, organism-specific biosystem (from WikiPathways)
    mRNA processing, organism-specific biosystemAdapted from Reactome, see: [http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_1675.1 REACT 1675.1] This process describes the conversion of precursor messenger RNA into mature messenge...
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
RNA binding IEA
Inferred from Electronic Annotation
more info
 
identical protein binding ISO
Inferred from Sequence Orthology
more info
 
mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
poly(A) RNA binding ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein heterodimerization activity ISO
Inferred from Sequence Orthology
more info
 
protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
negative regulation of translation IBA
Inferred from Biological aspect of Ancestor
more info
 
positive regulation of defense response to virus by host ISO
Inferred from Sequence Orthology
more info
 
xenophagy ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
dendrite IDA
Inferred from Direct Assay
more info
PubMed 
extracellular exosome ISO
Inferred from Sequence Orthology
more info
 
membrane ISO
Inferred from Sequence Orthology
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
polysome IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
fragile X mental retardation syndrome-related protein 2
Names
fragile X mental retardation gene 2, autosomal homolog
fragile X mental retardation-related protein 2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_011814.2NP_035944.2  fragile X mental retardation syndrome-related protein 2

    See identical proteins and their annotated locations for NP_035944.2

    Status: PROVISIONAL

    Source sequence(s)
    BC062971
    Consensus CDS
    CCDS24901.1
    UniProtKB/TrEMBL
    Q6P5B5
    Related
    ENSMUSP00000018909, OTTMUSP00000006226, ENSMUST00000018909, OTTMUST00000013449
    Conserved Domains (3) summary
    cd00105
    Location:296362
    KH-I; K homology RNA-binding domain, type I. KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins, transcription factors and post-transcriptional modifiers of mRNA. There are two different KH domains that ...
    pfam05641
    Location:69128
    Agenet; Agenet domain
    pfam12235
    Location:371416
    FXR1P_C; Fragile X-related 1 protein C terminal

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000077.6 Reference GRCm38.p3 C57BL/6J

    Range
    69632971..69653297
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. NW_001034697.1 Alternate Mm_Celera

    Range
    52..1372
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)