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Pfas phosphoribosylformylglycinamidine synthase (FGAR amidotransferase) [ Mus musculus (house mouse) ]

Gene ID: 237823, updated on 8-May-2016
Official Symbol
Pfasprovided by MGI
Official Full Name
phosphoribosylformylglycinamidine synthase (FGAR amidotransferase)provided by MGI
Primary source
MGI:MGI:2684864
See related
Ensembl:ENSMUSG00000020899 Vega:OTTMUSG00000005962
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm18; PURL; Sofa; FGAMS; FGARAT; FGAR-AT; 4432409B16Rik
Orthologs
Location:
11; 11 B3
Exon count:
28
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 11 NC_000077.6 (68985701..69008460, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (68799203..68821962, complement)

Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene solute carrier family 25, member 35 Neighboring gene RAN guanine nucleotide release factor Neighboring gene predicted gene, 32384 Neighboring gene microRNA 3062 Neighboring gene CTS telomere maintenance complex component 1 Neighboring gene nuclear encoded tRNA isoleucine 5 (anticodon AAT)

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
ATP binding IBA
Inferred from Biological aspect of Ancestor
more info
 
ligase activity IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
phosphoribosylformylglycinamidine synthase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
phosphoribosylformylglycinamidine synthase activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
'de novo' IMP biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
glutamine metabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
glutamine metabolic process ISO
Inferred from Sequence Orthology
more info
 
purine nucleotide biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
 
ribonucleoside monophosphate biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
 
ribonucleoside monophosphate biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
extracellular exosome ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
phosphoribosylformylglycinamidine synthase
Names
FGAM synthase
FGAR amidotransferase
formylglycinamide ribonucleotide amidotransferase
formylglycinamide ribotide amidotransferase
formylglycinamide ribotide synthetase
NP_001152991.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001159519.1NP_001152991.1  phosphoribosylformylglycinamidine synthase

    See identical proteins and their annotated locations for NP_001152991.1

    Status: VALIDATED

    Source sequence(s)
    AL645902, AL714000
    Consensus CDS
    CCDS48823.1
    UniProtKB/Swiss-Prot
    Q5SUR0
    Related
    ENSMUSP00000021282, OTTMUSP00000006164, ENSMUST00000021282, OTTMUST00000013311
    Conserved Domains (4) summary
    cd02203
    Location:218608
    PurL_repeat1; PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP, ...
    cd02204
    Location:706980
    PurL_repeat2; PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP, ...
    cd01740
    Location:10641329
    GATase1_FGAR_AT; Type 1 glutamine amidotransferase (GATase1)-like domain found in Formylglycinamide ribonucleotide amidotransferase
    TIGR01735
    Location:71332
    FGAM_synt; phosphoribosylformylglycinamidine synthase, single chain form

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000077.6 Reference GRCm38.p3 C57BL/6J

    Range
    68985701..69008460 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000033.1 Alternate Mm_Celera

    Range
    75928697..75951460 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)