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Ric8b RIC8 guanine nucleotide exchange factor B [ Mus musculus (house mouse) ]

Gene ID: 237422, updated on 8-May-2016
Official Symbol
Ric8bprovided by MGI
Official Full Name
RIC8 guanine nucleotide exchange factor Bprovided by MGI
Primary source
MGI:MGI:2682307
See related
Ensembl:ENSMUSG00000035620
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Ric-8; Ric-8b; BC051080
Orthologs
Location:
10; 10 C1
Exon count:
13
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 10 NC_000076.6 (84917249..85018337)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (84380361..84479192)

Chromosome 10 - NC_000076.6Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC102637873 Neighboring gene polymerase (RNA) III (DNA directed) polypeptide B Neighboring gene regulatory factor X, 4 (influences HLA class II expression) Neighboring gene predicted gene, 40728 Neighboring gene predicted gene, 40729 Neighboring gene predicted gene, 34633 Neighboring gene transmembrane protein 263 Neighboring gene four and a half LIM domains 4

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Targeted (3) 
Products Interactant Other Gene Complex Source Pubs Description

Homology

Clone Names

  • MGC58970

Gene Ontology Provided by MGI

Function Evidence Code Pubs
G-protein alpha-subunit binding IBA
Inferred from Biological aspect of Ancestor
more info
 
GTPase activator activity IBA
Inferred from Biological aspect of Ancestor
more info
 
guanyl-nucleotide exchange factor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
G-protein coupled receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
centrosome ISO
Inferred from Sequence Orthology
more info
 
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
Preferred Names
synembryn-B
Names
resistance to inhibitors of cholinesterase 8 homolog B
resistance to inhibitors of cholinesterase 8B

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001013441.2NP_001013459.1  synembryn-B isoform 1

    See identical proteins and their annotated locations for NP_001013459.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes isoform 1.
    Source sequence(s)
    AY940667, BC040762, BY272676
    Consensus CDS
    CCDS24084.1
    UniProtKB/Swiss-Prot
    Q80XE1
    Related
    ENSMUSP00000093032, ENSMUST00000095385
    Conserved Domains (1) summary
    pfam10165
    Location:66483
    Ric8; Guanine nucleotide exchange factor synembryn
  2. NM_183172.2NP_898995.1  synembryn-B isoform 2

    See identical proteins and their annotated locations for NP_898995.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) contains an alternate in-frame exon in the coding region compared to variant 1. It encodes isoform 2, which is longer than isoform 1.
    Source sequence(s)
    BC040762, BC051080, BY272676
    Consensus CDS
    CCDS24085.1
    UniProtKB/Swiss-Prot
    Q80XE1
    Related
    ENSMUSP00000046981, ENSMUST00000038523
    Conserved Domains (1) summary
    pfam10165
    Location:66541
    Ric8; Guanine nucleotide exchange factor synembryn

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000076.6 Reference GRCm38.p3 C57BL/6J

    Range
    84917249..85018337
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006513625.2XP_006513688.1  

    Conserved Domains (1) summary
    pfam10165
    Location:66524
    Ric8; Guanine nucleotide exchange factor synembryn

RNA

  1. XR_380392.2 RNA Sequence

  2. XR_380393.2 RNA Sequence

  3. XR_380394.2 RNA Sequence

Alternate Mm_Celera

Genomic

  1. AC_000032.1 Alternate Mm_Celera

    Range
    86895396..86996167
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)