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Adamts15 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 15 [ Mus musculus (house mouse) ]

Gene ID: 235130, updated on 8-May-2016
Official Symbol
Adamts15provided by MGI
Official Full Name
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 15provided by MGI
Primary source
MGI:MGI:2449569
See related
Ensembl:ENSMUSG00000033453
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Orthologs
Location:
9; 9 A4
Exon count:
11
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 9 NC_000075.6 (30899155..30922452, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (30706740..30730037, complement)

Chromosome 9 - NC_000075.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 31013 Neighboring gene predicted gene, 31140 Neighboring gene a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 8 Neighboring gene predicted gene, 29724 Neighboring gene zinc finger and BTB domain containing 44

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
endopeptidase activity IDA
Inferred from Direct Assay
more info
PubMed 
extracellular matrix binding IDA
Inferred from Direct Assay
more info
PubMed 
heparin binding IDA
Inferred from Direct Assay
more info
PubMed 
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
metalloendopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
metallopeptidase activity IEA
Inferred from Electronic Annotation
more info
 
peptidase activity IEA
Inferred from Electronic Annotation
more info
 
zinc ion binding IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
proteolysis IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cell surface IDA
Inferred from Direct Assay
more info
PubMed 
extracellular matrix IEA
Inferred from Electronic Annotation
more info
 
extracellular region IEA
Inferred from Electronic Annotation
more info
 
extracellular space IDA
Inferred from Direct Assay
more info
PubMed 
proteinaceous extracellular matrix IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
A disintegrin and metalloproteinase with thrombospondin motifs 15
Names
ADAM-TS 15
ADAM-TS15
ADAMTS-15
a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 15

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001024139.1NP_001019310.1  A disintegrin and metalloproteinase with thrombospondin motifs 15 precursor

    See identical proteins and their annotated locations for NP_001019310.1

    Status: PROVISIONAL

    Source sequence(s)
    BC094677
    Consensus CDS
    CCDS22945.1
    UniProtKB/Swiss-Prot
    P59384
    Related
    ENSMUSP00000067022, ENSMUST00000065112
    Conserved Domains (6) summary
    smart00209
    Location:519571
    TSP1; Thrombospondin type 1 repeats
    cd04273
    Location:218424
    ZnMc_ADAMTS_like; Zinc-dependent metalloprotease, ADAMTS_like subgroup. ADAMs (A Disintegrin And Metalloprotease) are glycoproteins, which play roles in cell signaling, cell fusion, and cell-cell interactions. This particular subfamily represents domain architectures that ...
    pfam01421
    Location:218427
    Reprolysin; Reprolysin (M12B) family zinc metalloprotease
    pfam01562
    Location:24157
    Pep_M12B_propep; Reprolysin family propeptide
    pfam05986
    Location:683801
    ADAM_spacer1; ADAM-TS Spacer 1
    cl15456
    Location:437506
    ADAM_CR; ADAM cysteine-rich

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000075.6 Reference GRCm38.p3 C57BL/6J

    Range
    30899155..30922452 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006510212.2XP_006510275.1  

    See identical proteins and their annotated locations for XP_006510275.1

    Conserved Domains (4) summary
    smart00209
    Location:188240
    TSP1; Thrombospondin type 1 repeats
    pfam05986
    Location:352470
    ADAM_spacer1; ADAM-TS Spacer 1
    cl15456
    Location:106175
    ADAM_CR; ADAM cysteine-rich
    cl00064
    Location:193
    ZnMc; Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which ...
  2. XM_006510214.2XP_006510277.1  

    See identical proteins and their annotated locations for XP_006510277.1

    Conserved Domains (4) summary
    smart00209
    Location:188240
    TSP1; Thrombospondin type 1 repeats
    pfam05986
    Location:352470
    ADAM_spacer1; ADAM-TS Spacer 1
    cl15456
    Location:106175
    ADAM_CR; ADAM cysteine-rich
    cl00064
    Location:193
    ZnMc; Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which ...
  3. XM_006510213.1XP_006510276.1  

    See identical proteins and their annotated locations for XP_006510276.1

    Conserved Domains (4) summary
    smart00209
    Location:188240
    TSP1; Thrombospondin type 1 repeats
    pfam05986
    Location:352470
    ADAM_spacer1; ADAM-TS Spacer 1
    cl15456
    Location:106175
    ADAM_CR; ADAM cysteine-rich
    cl00064
    Location:193
    ZnMc; Zinc-dependent metalloprotease. This super-family of metalloproteases contains two major branches, the astacin-like proteases and the adamalysin/reprolysin-like proteases. Both branches have wide phylogenetic distribution, and contain sub-families, which ...

Alternate Mm_Celera

Genomic

  1. AC_000031.1 Alternate Mm_Celera

    Range
    28160230..28183951 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)