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CSTF2T cleavage stimulation factor subunit 2, tau variant [ Homo sapiens (human) ]

Gene ID: 23283, updated on 26-May-2016
Official Symbol
CSTF2Tprovided by HGNC
Official Full Name
cleavage stimulation factor subunit 2, tau variantprovided by HGNC
Primary source
HGNC:HGNC:17086
See related
Ensembl:ENSG00000177613 HPRD:09900; MIM:611968; Vega:OTTHUMG00000018246
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CstF-64T
Orthologs
Location:
10q11
Exon count:
1
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 10 NC_000010.11 (51695486..51699595, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (53455246..53459355, complement)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene protein kinase, cGMP-dependent, type I Neighboring gene microRNA 605 Neighboring gene Ras suppressor protein 1 pseudogene 3 Neighboring gene uncharacterized LOC105378304 Neighboring gene uncharacterized LOC105378303

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

NHGRI GWAS Catalog

Description
Genetic analysis of the pathogenic molecular sub-phenotype interferon-alpha identifies multiple novel loci involved in systemic lupus erythematosus.
NHGRI GWA Catalog
Genome-wide association study identifies multiple loci associated with both mammographic density and breast cancer risk.
NHGRI GWA Catalog
  • mRNA processing, organism-specific biosystem (from WikiPathways)
    mRNA processing, organism-specific biosystemThis process describes the conversion of precursor messenger RNA into mature messenger RNA (mRNA). The pre-mRNA molecule undergoes three main modifications. These modifications are 5' capping, 3' po...
  • mRNA surveillance pathway, organism-specific biosystem (from KEGG)
    mRNA surveillance pathway, organism-specific biosystemThe mRNA surveillance pathway is a quality control mechanism that detects and degrades abnormal mRNAs. These pathways include nonsense-mediated mRNA decay (NMD), nonstop mRNA decay (NSD), and no-go ...
  • mRNA surveillance pathway, conserved biosystem (from KEGG)
    mRNA surveillance pathway, conserved biosystemThe mRNA surveillance pathway is a quality control mechanism that detects and degrades abnormal mRNAs. These pathways include nonsense-mediated mRNA decay (NMD), nonstop mRNA decay (NSD), and no-go ...
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • KIAA0689, DKFZp434C1013

Gene Ontology Provided by GOA

Function Evidence Code Pubs
mRNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
poly(A) RNA binding IDA
Inferred from Direct Assay
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
pre-mRNA cleavage required for polyadenylation IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
intracellular IDA
Inferred from Direct Assay
more info
 
mRNA cleavage and polyadenylation specificity factor complex IBA
Inferred from Biological aspect of Ancestor
more info
 
Preferred Names
cleavage stimulation factor subunit 2 tau variant
Names
CF-1 64 kDa subunit tau
CSTF 64 kDa subunit tau
cleavage stimulation factor 64 kDa subunit tau
cleavage stimulation factor subunit 2 tau
cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau
cleavage stimulation factor, 3' pre-RNA, subunit 2, tau
tauCstF-64

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_015235.2NP_056050.1  cleavage stimulation factor subunit 2 tau variant

    See identical proteins and their annotated locations for NP_056050.1

    Status: VALIDATED

    Source sequence(s)
    AB014589, AL136747, BI962669, BU743103, BX455090
    Consensus CDS
    CCDS7245.1
    UniProtKB/Swiss-Prot
    Q9H0L4
    Related
    ENSP00000332444, OTTHUMP00000019616, ENST00000331173, OTTHUMT00000048097
    Conserved Domains (4) summary
    pfam14304
    Location:570613
    CSTF_C; Transcription termination and cleavage factor C-terminal
    smart00360
    Location:1789
    RRM; RNA recognition motif
    cd12671
    Location:1892
    RRM_CSTF2_CSTF2T; RNA recognition motif in cleavage stimulation factor subunit 2 (CSTF2), cleavage stimulation factor subunit 2 tau variant (CSTF2T) and similar proteins
    pfam14327
    Location:109193
    CSTF2_hinge; Hinge domain of cleavage stimulation factor subunit 2

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p2 Primary Assembly

    Range
    51695486..51699595 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate CHM1_1.1

Genomic

  1. NC_018921.2 Alternate CHM1_1.1

    Range
    53737028..53741141 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)