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PLCB1 phospholipase C, beta 1 (phosphoinositide-specific) [ Homo sapiens (human) ]

Gene ID: 23236, updated on 23-Nov-2014
Official Symbol
PLCB1provided by HGNC
Official Full Name
phospholipase C, beta 1 (phosphoinositide-specific)provided by HGNC
Primary source
HGNC:HGNC:15917
Locus tag
RP4-654A7.1
See related
Ensembl:ENSG00000182621; HPRD:06177; MIM:607120; Vega:OTTHUMG00000031849
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
PLC-I; EIEE12; PI-PLC; PLC154; PLCB1A; PLCB1B; PLC-154
Summary
The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
See PLCB1 in Epigenomics, MapViewer
Location:
20p12
Exon count:
36
Annotation release Status Assembly Chr Location
106 current GRCh38 (GCF_000001405.26) 20 NC_000020.11 (8132265..8884900)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 20 NC_000020.10 (8112912..8865547)

Chromosome 20 - NC_000020.11Genomic Context describing neighboring genes Neighboring gene thioredoxin-related transmembrane protein 4 Neighboring gene phosphorylase kinase, beta pseudogene 1 Neighboring gene RNA, U105B small nucleolar Neighboring gene phospholipase C, beta 4 Neighboring gene LAMP5 antisense RNA 1 Neighboring gene lysosomal-associated membrane protein family, member 5

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Associated conditions

Description Tests
Early infantile epileptic encephalopathy 12
MedGen: C3150988 OMIM: 613722 GeneReviews: Not available
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NHGRI GWAS Catalog

Description
A genome-wide association study for irinotecan-related severe toxicities in patients with advanced non-small-cell lung cancer.
NHGRI GWA Catalog
A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.
NHGRI GWA Catalog
Common genetic variation and performance on standardized cognitive tests.
NHGRI GWA Catalog
Genome-wide association analyses in East Asians identify new susceptibility loci for colorectal cancer.
NHGRI GWA Catalog
TSPYL5 SNPs: association with plasma estradiol concentrations and aromatase expression.
NHGRI GWA Catalog
Variability in the common genetic architecture of social-communication spectrum phenotypes during childhood and adolescence.
NHGRI GWA Catalog

Protein interactions

Protein Gene Interaction Pubs
Envelope surface glycoprotein gp120 env Nuclear PI-PLC beta 1 plays as a new intermediate in the gp120-triggered PC-PLC-driven signal transduction pathway leading to CCL2 secretion in macrophages PubMed
env HIV-1 gp120 induces nuclear localization of the phosphoinositide-specific phospholipase C (PI-PLC) beta 1 isozyme in MDMs, which requires activation of the MAPK ERK1/2 pathway PubMed
env The interaction of HIV-1 gp120 with CCR5 triggers PC-PLC activation and CCL2 secretion in human monocyte-derived macrophages PubMed
env Phosphatidylcholine-specific phospholipase C (PC-PLC) signaling pathway modulates HIV-1 gp120-induced CCL2 production in human monocyte-derived macrophages PubMed
env PC-PLC is an upstream regulator of HIV-1 gp120-mediated NF-kappaB activation in human monocyte-derived macrophages PubMed
env HIV-1 gp120 induces cellular relocalization of PC-PLC from the cytoplasm to the plasma membrane, and stimulates its enzymatic activity in human monocyte-derived macrophages PubMed
env PLC-beta activation and intracellular Ca2+ release are required for HIV-1 gp120-mediated Rac-1 activation and membrane fusion via the G-alpha(q/11) family of G proteins PubMed
env HIV-1 envelope glycoproteins gp120 and gp160 directly and specifically impair the CD3/TcR-mediated activation of phospholipase C (PLC) via the CD4 molecule in uninfected T cells PubMed
Tat tat Phospholipase C/protein kinase C pathway-dependent phosphorylation of p44/42 and JNK MAP kinases is partially involved in IL-1beta induction by HIV-1 Tat PubMed
tat HIV-1 Tat induces release of calcium and TNF-alpha production, an effect mediated at least in part by activation of phospholipase C PubMed
Vif vif HIV-1 Vif downregulates the expression of phospholipase C, beta 1 (PLCB1) in Vif-expression T cells PubMed

Go to the HIV-1, Human Interaction Database

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  • Endothelins, organism-specific biosystem (from Pathway Interaction Database)
    Endothelins, organism-specific biosystem
    Endothelins
  • Estrogen signaling pathway, organism-specific biosystem (from KEGG)
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  • G beta:gamma signalling through PLC beta, organism-specific biosystem (from REACTOME)
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  • G-protein beta:gamma signalling, organism-specific biosystem (from REACTOME)
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    Inositol phosphate metabolism, organism-specific biosystem
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  • Long-term depression, conserved biosystem (from KEGG)
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  • Long-term potentiation, organism-specific biosystem (from KEGG)
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  • Metabolic pathways, organism-specific biosystem (from KEGG)
    Metabolic pathways, organism-specific biosystem
    Metabolic pathways
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  • Oxytocin signaling pathway, conserved biosystem (from KEGG)
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  • PLC beta mediated events, organism-specific biosystem (from REACTOME)
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  • Phosphatidylinositol signaling system, organism-specific biosystem (from KEGG)
    Phosphatidylinositol signaling system, organism-specific biosystem
    Phosphatidylinositol signaling system
  • Phosphatidylinositol signaling system, conserved biosystem (from KEGG)
    Phosphatidylinositol signaling system, conserved biosystem
    Phosphatidylinositol signaling system
  • Plasma membrane estrogen receptor signaling, organism-specific biosystem (from Pathway Interaction Database)
    Plasma membrane estrogen receptor signaling, organism-specific biosystem
    Plasma membrane estrogen receptor signaling
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  • Rap1 signaling pathway, organism-specific biosystem (from KEGG)
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  • Rap1 signaling pathway, conserved biosystem (from KEGG)
    Rap1 signaling pathway, conserved biosystemRap1 is a small GTPase that controls diverse processes, such as cell adhesion, cell-cell junction formation and cell polarity. Like all G proteins, Rap1 cycles between an inactive GDP-bound and an ac...
  • Regulation of insulin secretion, organism-specific biosystem (from REACTOME)
    Regulation of insulin secretion, organism-specific biosystemPancreatic beta cells integrate signals from several metabolites and hormones to control the secretion of insulin. In general, glucose triggers insulin secretion while other factors can amplify or in...
  • Retrograde endocannabinoid signaling, organism-specific biosystem (from KEGG)
    Retrograde endocannabinoid signaling, organism-specific biosystemEndogenous cannabinoids (endocannabinoids) serve as retrograde messengers at synapses in various regions of the brain. The family of endocannabinoids includes at least five derivatives of arachidonic...
  • Retrograde endocannabinoid signaling, conserved biosystem (from KEGG)
    Retrograde endocannabinoid signaling, conserved biosystemEndogenous cannabinoids (endocannabinoids) serve as retrograde messengers at synapses in various regions of the brain. The family of endocannabinoids includes at least five derivatives of arachidonic...
  • Salivary secretion, organism-specific biosystem (from KEGG)
    Salivary secretion, organism-specific biosystemSaliva has manifold functions in maintaining the integrity of the oral tissues, in protecting teeth from caries, in the tasting and ingestion of food, in speech and in the tolerance of tenures, for e...
  • Salivary secretion, conserved biosystem (from KEGG)
    Salivary secretion, conserved biosystemSaliva has manifold functions in maintaining the integrity of the oral tissues, in protecting teeth from caries, in the tasting and ingestion of food, in speech and in the tolerance of tenures, for e...
  • Serotonergic synapse, organism-specific biosystem (from KEGG)
    Serotonergic synapse, organism-specific biosystemSerotonin (5-Hydroxytryptamine, 5-HT) is a monoamine neurotransmitter that plays important roles in physiological functions such as learning and memory, emotion, sleep, pain, motor function and endoc...
  • Signal Transduction, organism-specific biosystem (from REACTOME)
    Signal Transduction, organism-specific biosystemSignal transduction is a process in which extracellular signals elicit changes in cell state and activity. Transmembrane receptors sense changes in the cellular environment by binding ligands, such a...
  • Signal Transduction of S1P Receptor, organism-specific biosystem (from WikiPathways)
    Signal Transduction of S1P Receptor, organism-specific biosystemMetabolism of sphingomyelin by the sphingomyelinase, ceramidase (Cer'ase) and the sphingosine kinase (SK) enzymes results in formation of S1P and receptor activation. Autocrine and paracrine modes of...
  • Signaling by GPCR, organism-specific biosystem (from REACTOME)
    Signaling by GPCR, organism-specific biosystemG protein-coupled receptors (GPCRs; 7TM receptors; seven transmembrane domain receptors; heptahelical receptors; G protein-linked receptors [GPLR]) are the largest family of transmembrane receptors i...
  • Signaling by Wnt, organism-specific biosystem (from REACTOME)
    Signaling by Wnt, organism-specific biosystemWNT signaling pathways control a wide range of developmental and adult process in metozoans including cell proliferation, cell fate decisions, cell polarity and stem cell maintenance (reviewed in Sai...
  • Synthesis of IP3 and IP4 in the cytosol, organism-specific biosystem (from REACTOME)
    Synthesis of IP3 and IP4 in the cytosol, organism-specific biosystemAn array of inositol trisphosphate (IP3) and tetrakisphosphate (IP4) molecules are synthesised by the action of various kinases and phosphatases in the cytosol (Irvine & Schell 2001, Bunney & Katan 2...
  • TSH signaling pathway, organism-specific biosystem (from WikiPathways)
    TSH signaling pathway, organism-specific biosystemHuman thyroid stimulating hormone (TSH) is a glycoprotein secreted by the anterior part of the pituitary gland (1). TSH plays an important physiological role in the regulation of the hypothalamic-pit...
  • Thyroid hormone signaling pathway, organism-specific biosystem (from KEGG)
    Thyroid hormone signaling pathway, organism-specific biosystemThe thyroid hormones (THs) are important regulators of growth, development and metabolism. The action of TH is mainly mediated by T3 (3,5,3'-triiodo-L-thyronine). Thyroid hormones, L-thyroxine (T4) a...
  • Thyroid hormone synthesis, organism-specific biosystem (from KEGG)
    Thyroid hormone synthesis, organism-specific biosystemThyroid hormones triiodothyronine (T3) and thyroxine (T4) are essential for normal development, growth and metabolic homeostasis in all vertebrates, and synthesized in the thyroid gland. The function...
  • Thyroid hormone synthesis, conserved biosystem (from KEGG)
    Thyroid hormone synthesis, conserved biosystemThyroid hormones triiodothyronine (T3) and thyroxine (T4) are essential for normal development, growth and metabolic homeostasis in all vertebrates, and synthesized in the thyroid gland. The function...
  • Transmission across Chemical Synapses, organism-specific biosystem (from REACTOME)
    Transmission across Chemical Synapses, organism-specific biosystemChemical synapses are specialized junctions that are used for communication between neurons, neurons and muscle or gland cells. The synapse involves a pre-synaptic neuron and a post-synaptic neuron,...
  • Vascular smooth muscle contraction, organism-specific biosystem (from KEGG)
    Vascular smooth muscle contraction, organism-specific biosystemThe vascular smooth muscle cell (VSMC) is a highly specialized cell whose principal function is contraction. On contraction, VSMCs shorten, thereby decreasing the diameter of a blood vessel to regula...
  • Vascular smooth muscle contraction, conserved biosystem (from KEGG)
    Vascular smooth muscle contraction, conserved biosystemThe vascular smooth muscle cell (VSMC) is a highly specialized cell whose principal function is contraction. On contraction, VSMCs shorten, thereby decreasing the diameter of a blood vessel to regula...
  • Wnt signaling pathway, organism-specific biosystem (from KEGG)
    Wnt signaling pathway, organism-specific biosystemWnt proteins are secreted morphogens that are required for basic developmental processes, such as cell-fate specification, progenitor-cell proliferation and the control of asymmetric cell division, i...
  • Wnt signaling pathway, conserved biosystem (from KEGG)
    Wnt signaling pathway, conserved biosystemWnt proteins are secreted morphogens that are required for basic developmental processes, such as cell-fate specification, progenitor-cell proliferation and the control of asymmetric cell division, i...
  • beta-catenin independent WNT signaling, organism-specific biosystem (from REACTOME)
    beta-catenin independent WNT signaling, organism-specific biosystemHumans and mice have 19 identified WNT proteins that were originally classified as either 'canonical' or 'non-canonical' depending upon whether they were able to transform the mouse mammary epithelia...
  • cGMP-PKG signaling pathway, organism-specific biosystem (from KEGG)
    cGMP-PKG signaling pathway, organism-specific biosystemCyclic GMP (cGMP) is the intracellular second messenger that mediates the action of nitric oxide (NO) and natriuretic peptides (NPs), regulating a broad array of physiologic processes. The elevated i...
  • cGMP-PKG signaling pathway, conserved biosystem (from KEGG)
    cGMP-PKG signaling pathway, conserved biosystemCyclic GMP (cGMP) is the intracellular second messenger that mediates the action of nitric oxide (NO) and natriuretic peptides (NPs), regulating a broad array of physiologic processes. The elevated i...
  • phospholipases, organism-specific biosystem (from BIOCYC)
    phospholipases, organism-specific biosystem
    phospholipases
  • superpathway of inositol phosphate compounds, organism-specific biosystem (from BIOCYC)
    superpathway of inositol phosphate compounds, organism-specific biosystem
    superpathway of inositol phosphate compounds
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • FLJ45792

Gene Ontology Provided by GOA

Function Evidence Code Pubs
GTPase activator activity IDA
Inferred from Direct Assay
more info
PubMed 
calcium ion binding IEA
Inferred from Electronic Annotation
more info
 
calmodulin binding IPI
Inferred from Physical Interaction
more info
PubMed 
enzyme binding IPI
Inferred from Physical Interaction
more info
PubMed 
lamin binding IEA
Inferred from Electronic Annotation
more info
 
phosphatidylinositol phospholipase C activity ISS
Inferred from Sequence or Structural Similarity
more info
 
phosphatidylinositol phospholipase C activity NAS
Non-traceable Author Statement
more info
PubMed 
phosphatidylinositol-4,5-bisphosphate binding IDA
Inferred from Direct Assay
more info
PubMed 
protein homodimerization activity ISS
Inferred from Sequence or Structural Similarity
more info
 
signal transducer activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
G-protein coupled acetylcholine receptor signaling pathway ISS
Inferred from Sequence or Structural Similarity
more info
 
G2/M transition of mitotic cell cycle ISS
Inferred from Sequence or Structural Similarity
more info
 
activation of meiosis involved in egg activation ISS
Inferred from Sequence or Structural Similarity
more info
 
cerebral cortex development ISS
Inferred from Sequence or Structural Similarity
more info
 
fat cell differentiation IEA
Inferred from Electronic Annotation
more info
 
glutamate receptor signaling pathway ISS
Inferred from Sequence or Structural Similarity
more info
 
inositol phosphate metabolic process TAS
Traceable Author Statement
more info
 
insulin-like growth factor receptor signaling pathway ISS
Inferred from Sequence or Structural Similarity
more info
 
interleukin-1-mediated signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
interleukin-12-mediated signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
interleukin-15-mediated signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 
lipid catabolic process IEA
Inferred from Electronic Annotation
more info
 
memory ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of monocyte extravasation ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of transcription, DNA-templated ISS
Inferred from Sequence or Structural Similarity
more info
 
phosphatidylinositol metabolic process ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of CD24 biosynthetic process ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of G1/S transition of mitotic cell cycle ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of GTPase activity IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of JNK cascade IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of acrosome reaction ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of developmental growth ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of embryonic development ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of interleukin-12 production ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of myoblast differentiation ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of transcription, DNA-templated ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of G-protein coupled receptor protein signaling pathway ISS
Inferred from Sequence or Structural Similarity
more info
 
regulation of fertilization ISS
Inferred from Sequence or Structural Similarity
more info
 
signal transduction NAS
Non-traceable Author Statement
more info
PubMed 
small molecule metabolic process TAS
Traceable Author Statement
more info
 
synaptic transmission TAS
Traceable Author Statement
more info
 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytosol TAS
Traceable Author Statement
more info
 
extracellular vesicular exosome IDA
Inferred from Direct Assay
more info
PubMed 
nuclear chromatin ISS
Inferred from Sequence or Structural Similarity
more info
 
nuclear membrane IEA
Inferred from Electronic Annotation
more info
 
nuclear speck IDA
Inferred from Direct Assay
more info
PubMed 
nucleus NAS
Non-traceable Author Statement
more info
PubMed 
Preferred Names
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1
Names
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1
PLC-beta-1
phospholipase C-I
phosphoinositidase C
inositoltrisphosphohydrolase
triphosphoinositide phosphodiesterase
monophosphatidylinositol phosphodiesterase
1-phosphatidyl-D-myo-inositol-4,5-bisphosphate
NP_056007.1
NP_877398.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_028168.1 

    Range
    4617..757252
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_015192.3NP_056007.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform a

    See proteins identical to NP_056007.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (a).
    Source sequence(s)
    AB011153, AL049593, AY004175, BQ184058
    Consensus CDS
    CCDS13102.1
    UniProtKB/Swiss-Prot
    Q9NQ66
    Related
    ENSP00000338185, OTTHUMP00000030237, ENST00000338037, OTTHUMT00000077938
    Conserved Domains (7) summary
    pfam09279
    Location:224315
    EF-hand_like; Phosphoinositide-specific phospholipase C, efhand-like
    cd00275
    Location:677796
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:316643
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    PLN02952
    Location:216784
    PLN02952; phosphoinositide phospholipase C
    cd13361
    Location:22148
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    pfam06631
    Location:904946
    DUF1154; Protein of unknown function (DUF1154)
    pfam08703
    Location:9971167
    PLC-beta_C; PLC-beta C terminal
  2. NM_182734.2NP_877398.1  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 isoform b

    See proteins identical to NP_877398.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) includes an alternate exon in the 3' end compared to variant 1. This exon contains an in-frame stop codon, and the resulting isoform (b) is shorter and has a distinct C-terminus compared to isoform a.
    Source sequence(s)
    AB011153, AJ278314, AL049593, BQ184058
    Consensus CDS
    CCDS13103.1
    UniProtKB/Swiss-Prot
    Q9NQ66
    Related
    ENSP00000367908, OTTHUMP00000030239, ENST00000378641, OTTHUMT00000077940
    Conserved Domains (7) summary
    pfam09279
    Location:224315
    EF-hand_like; Phosphoinositide-specific phospholipase C, efhand-like
    cd00275
    Location:677796
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:316643
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    PLN02952
    Location:216784
    PLN02952; phosphoinositide phospholipase C
    cd13361
    Location:22148
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    pfam06631
    Location:904946
    DUF1154; Protein of unknown function (DUF1154)
    pfam08703
    Location:9971165
    PLC-beta_C; PLC-beta C terminal

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Alternate HuRef

Genomic

  1. AC_000152.1 

    Range
    8064325..8817514
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38 Primary Assembly

Genomic

  1. NC_000020.11 

    Range
    8132265..8884900
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006723555.1XP_006723618.1  

    See proteins identical to XP_006723618.1

    UniProtKB/Swiss-Prot
    Q9NQ66
    Related
    ENSP00000367904, OTTHUMP00000030238, ENST00000378637, OTTHUMT00000077939
    Conserved Domains (7) summary
    pfam09279
    Location:224315
    EF-hand_like; Phosphoinositide-specific phospholipase C, efhand-like
    cd00275
    Location:677796
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:316643
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    PLN02952
    Location:216784
    PLN02952; phosphoinositide phospholipase C
    cd13361
    Location:22148
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain
    pfam06631
    Location:904946
    DUF1154; Protein of unknown function (DUF1154)
    pfam08703
    Location:9971165
    PLC-beta_C; PLC-beta C terminal
  2. XM_005260681.2XP_005260738.1  

    Conserved Domains (5) summary
    pfam09279
    Location:224315
    EF-hand_like; Phosphoinositide-specific phospholipase C, efhand-like
    cd00275
    Location:677796
    C2_PLC_like; C2 domain present in Phosphoinositide-specific phospholipases C (PLC)
    cd08591
    Location:316643
    PI-PLCc_beta; Catalytic domain of metazoan phosphoinositide-specific phospholipase C-beta
    PLN02952
    Location:216784
    PLN02952; phosphoinositide phospholipase C
    cd13361
    Location:22148
    PH_PLC_beta; Phospholipase C-beta (PLC-beta) pleckstrin homology (PH) domain

Alternate CHM1_1.1

Genomic

  1. NC_018931.2 

    Range
    8113481..8866748
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)