These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in this
section to the one reported in Genomic regions, transcripts, and products above.
mRNA and Protein(s)
-
NM_178039.2 → NP_829883.1 ELKS/Rab6-interacting/CAST family member 1 isoform delta
Status: REVIEWED
- Description
- Transcript Variant: This variant (delta) lacks an alternate in-frame exon in the coding region, compared to variant epsilon, resulting in a shorter isoform (delta), compared to isoform epsilon.
- Source sequence(s)
-
AB053470, AC004671, AC004803, BM984956
- Consensus CDS
-
CCDS53732.1
- UniProtKB/Swiss-Prot
-
Q8IUD2
- Related
- ENSP00000438546, OTTHUMP00000160633, ENST00000543086, OTTHUMT00000252446
- Conserved Domains (2) summary
-
- pfam10174
Location:154 – 954
Blast Score: 1397
- Cast; RIM-binding protein of the cytomatrix active zone
- pfam09457
Location:1040 – 1080
Blast Score: 97
- RBD-FIP; FIP domain
-
NM_178040.2 → NP_829884.1 ELKS/Rab6-interacting/CAST family member 1 isoform epsilon
Status: REVIEWED
- Description
- Transcript Variant: This variant (epsilon) encodes the longest isoform (epsilon).
- Source sequence(s)
-
AB053471, AC004671, AC004803, BC132782, BM984956
- Consensus CDS
-
CCDS8508.1
- UniProtKB/Swiss-Prot
-
Q8IUD2
- Related
- ENSP00000354158, OTTHUMP00000238060, ENST00000360905, OTTHUMT00000398382
- Conserved Domains (2) summary
-
- pfam10174
Location:154 – 982
Blast Score: 1339
- Cast; RIM-binding protein of the cytomatrix active zone
- pfam09457
Location:1068 – 1108
Blast Score: 97
- RBD-FIP; FIP domain
RNA
-
NR_027946.1 RNA Sequence
- Description
- Transcript Variant: This variant (alpha) uses an alternative 5' splice site, lacks two exons, and contains two additional exons, compared to variant epsilon. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant epsilon, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AB015617, AC004671, AC004803, BM984956
-
NR_027948.1 RNA Sequence
- Description
- Transcript Variant: This variant (beta) uses an alternative 5' splice site, lacks one exon, and contains two additional exons, compared to variant epsilon. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant epsilon, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AB053468, AC004671, AC004803, BM984956
-
NR_027949.1 RNA Sequence
- Description
- Transcript Variant: This variant (gamma) lacks five exons and contains two additional exons, compared to variant epsilon. This variant is represented as non-coding because the use of the 5'-most supported translational start codon, as used in variant epsilon, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
- Source sequence(s)
-
AB053469, AC004671, AC004803, BM984956
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs
for chromosomes and scaffolds (contigs) from both reference and alternate assemblies.
Model RNAs and proteins are also reported here.
Reference GRCh37.p5 Primary Assembly
Genomic
-
NC_000012.11 Reference GRCh37.p5 Primary Assembly
- Range
- 1100404..1605099
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate HuRef
Genomic
-
AC_000144.1 Alternate HuRef
- Range
- 952225..1457980
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)