Format

Send to:

Choose Destination

Szt2 seizure threshold 2 [ Mus musculus (house mouse) ]

Gene ID: 230676, updated on 26-May-2016
Official Symbol
Szt2provided by MGI
Official Full Name
seizure threshold 2provided by MGI
Primary source
MGI:MGI:3033336
See related
Ensembl:ENSMUSG00000033253 Vega:OTTMUSG00000008774
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
TIGR; 6430407N22; ENSMUSG00000058432
Summary
This gene encodes a protein associated with low seizure threshold in mice and may contribute to susceptibility to epilepsy. [provided by RefSeq, Aug 2011]
Orthologs
Location:
4; 4 D2.1
Exon count:
72
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 4 NC_000070.6 (118362740..118409276, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (118035350..118081868, complement)

Chromosome 4 - NC_000070.6Genomic Context describing neighboring genes Neighboring gene protein tyrosine phosphatase, receptor type, F Neighboring gene predicted gene, 40235 Neighboring gene predicted gene, 35138 Neighboring gene hydroxypyruvate isomerase (putative) Neighboring gene mediator complex subunit 8 Neighboring gene elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1 Neighboring gene cell division cycle 20

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • MGC69654

Gene Ontology Provided by MGI

Function Evidence Code Pubs
molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
central nervous system development IMP
Inferred from Mutant Phenotype
more info
PubMed 
corpus callosum morphogenesis ISO
Inferred from Sequence Orthology
more info
 
pigmentation IMP
Inferred from Mutant Phenotype
more info
PubMed 
post-embryonic development IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of superoxide dismutase activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
extracellular exosome ISO
Inferred from Sequence Orthology
more info
 
peroxisome IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
protein SZT2
Names
Seizure threshold 2 protein
Transcript increased in glutamate resistance

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_198170.4NP_937813.3  protein SZT2

    See identical proteins and their annotated locations for NP_937813.3

    Status: REVIEWED

    Source sequence(s)
    CJ191816, FJ998170
    Consensus CDS
    CCDS51283.1
    UniProtKB/Swiss-Prot
    A2A9C3
    Related
    ENSMUSP00000074862, OTTMUSP00000009149, ENSMUST00000075406, OTTMUST00000019936

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000070.6 Reference GRCm38.p3 C57BL/6J

    Range
    118362740..118409276 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006503012.1XP_006503075.1  

RNA

  1. XR_867847.1 RNA Sequence

Alternate Mm_Celera

Genomic

  1. AC_000026.1 Alternate Mm_Celera

    Range
    117085120..117131926 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)