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Rap1gds1 RAP1, GTP-GDP dissociation stimulator 1 [ Mus musculus (house mouse) ]

Gene ID: 229877, updated on 8-May-2016
Official Symbol
Rap1gds1provided by MGI
Official Full Name
RAP1, GTP-GDP dissociation stimulator 1provided by MGI
Primary source
MGI:MGI:2385189
See related
Ensembl:ENSMUSG00000028149 Vega:OTTMUSG00000052979
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
GDS1; BC011279
Orthologs
Location:
3; 3 H1
Exon count:
16
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 3 NC_000069.6 (138925897..139075201, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (138588870..138738163, complement)

Chromosome 3 - NC_000069.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930425O10 gene Neighboring gene tetraspanin 5 Neighboring gene synaptic nuclear envelope 1 pseudogene Neighboring gene predicted gene 4862 Neighboring gene sperm tail PG rich repeat containing 2 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 

Markers

Homology

Clone Names

  • MGC18981

Gene Ontology Provided by MGI

Function Evidence Code Pubs
molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
myosin filament assembly ISO
Inferred from Sequence Orthology
more info
 
negative regulation of endoplasmic reticulum calcium ion concentration ISO
Inferred from Sequence Orthology
more info
 
positive regulation of GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
positive regulation of GTPase activity ISO
Inferred from Sequence Orthology
more info
 
positive regulation of mitochondrial calcium ion concentration ISO
Inferred from Sequence Orthology
more info
 
small GTPase mediated signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
 
vascular smooth muscle contraction ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 
cytosol ISO
Inferred from Sequence Orthology
more info
 
endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
extracellular exosome ISO
Inferred from Sequence Orthology
more info
 
mitochondrion ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
rap1 GTPase-GDP dissociation stimulator 1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001040690.2NP_001035780.1  rap1 GTPase-GDP dissociation stimulator 1 isoform a

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (a).
    Source sequence(s)
    AC110574, AC119881, AK160989, AK164159, AK172052, BB400575
    Consensus CDS
    CCDS51083.1
    UniProtKB/TrEMBL
    E9Q912, Q3TA69, Q3TPS9, Q3TU36
    Related
    ENSMUSP00000096173, OTTMUSP00000070666, ENSMUST00000098574, OTTMUST00000132552
    Conserved Domains (1) summary
    cd00020
    Location:317430
    ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
  2. NM_001286759.1NP_001273688.1  rap1 GTPase-GDP dissociation stimulator 1 isoform c

    See identical proteins and their annotated locations for NP_001273688.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) uses an alternate in-frame splice site in the 3' coding region compared to variant 1. The encoded protein (isoform c) is shorter than isoform a.
    Source sequence(s)
    AC110574, AK160989, AK172052, BB400575
    Consensus CDS
    CCDS80033.1
    UniProtKB/TrEMBL
    Q3TA69, Q3TU36
    Related
    ENSMUSP00000143181, OTTMUSP00000070667, ENSMUST00000196280, OTTMUST00000132553
    Conserved Domains (1) summary
    cd00020
    Location:317430
    ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
  3. NM_145544.3NP_663519.2  rap1 GTPase-GDP dissociation stimulator 1 isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region compared to variant 1. The encoded protein (isoform b) is shorter than isoform a.
    Source sequence(s)
    AC110574, AC113307, AC119881
    Consensus CDS
    CCDS51082.1
    UniProtKB/TrEMBL
    E9Q6Q4
    Related
    ENSMUSP00000029796, OTTMUSP00000070668, ENSMUST00000029796, OTTMUST00000132554
    Conserved Domains (1) summary
    cd00020
    Location:268381
    ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000069.6 Reference GRCm38.p3 C57BL/6J

    Range
    138925897..139075201 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006501428.2XP_006501491.1  

    See identical proteins and their annotated locations for XP_006501491.1

    Conserved Domains (1) summary
    cd00020
    Location:139252
    ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...
  2. XM_006501429.2XP_006501492.1  

    See identical proteins and their annotated locations for XP_006501492.1

    Conserved Domains (1) summary
    cd00020
    Location:139252
    ARM; Armadillo/beta-catenin-like repeats. An approximately 40 amino acid long tandemly repeated sequence motif first identified in the Drosophila segment polarity gene armadillo; these repeats were also found in the mammalian armadillo homolog beta-catenin, ...

Alternate Mm_Celera

Genomic

  1. AC_000025.1 Alternate Mm_Celera

    Range
    145353555..145478788 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)