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Smg5 Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans) [ Mus musculus (house mouse) ]

Gene ID: 229512, updated on 18-Oct-2014
Official Symbol
Smg5provided by MGI
Official Full Name
Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans)provided by MGI
Primary source
MGI:MGI:2447364
See related
Ensembl:ENSMUSG00000001415
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
BC024683; mKIAA1089
See Smg5 in Epigenomics, MapViewer
Location:
3 F1; 3
Exon count:
23
Annotation release Status Assembly Chr Location
104 current GRCm38.p2 (GCF_000001635.22) 3 NC_000069.6 (88336260..88362338)

Chromosome 3 - NC_000069.6Genomic Context describing neighboring genes Neighboring gene glycosylated lysosomal membrane protein Neighboring gene transmembrane protein 79 Neighboring gene progestin and adipoQ receptor family member VI Neighboring gene bone gamma-carboxyglutamate protein 3

Markers

Homology

Clone Names

  • MGC30464, MGC56792, MGC118167

Gene Ontology Provided by MGI

Function Evidence Code Pubs
protein phosphatase 2A binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IEA
Inferred from Electronic Annotation
more info
 
regulation of dephosphorylation ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
nucleus ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
protein SMG5
Names
protein SMG5
EST1-like protein B

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_178246.3NP_839977.2  protein SMG5

    See proteins identical to NP_839977.2

    Status: VALIDATED

    Source sequence(s)
    AK133688, AK143911, AV146226, BB869373, BC066787
    Consensus CDS
    CCDS38480.1
    UniProtKB/TrEMBL
    Q3UZS1
    UniProtKB/Swiss-Prot
    Q6ZPY2
    Related
    ENSMUSP00000001451, ENSMUST00000001451
    Conserved Domains (3) summary
    pfam10373
    Location:197411
    EST1_DNA_bind; Est1 DNA/RNA binding domain
    pfam10374
    Location:76192
    EST1; Telomerase activating protein Est1
    cl14812
    Location:8561014
    PIN_SF; PIN (PilT N terminus) domain: Superfamily

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p2 C57BL/6J

Genomic

  1. NC_000069.6 

    Range
    88336260..88362338
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006501346.1XP_006501409.1  

    Conserved Domains (2) summary
    pfam10373
    Location:197411
    EST1_DNA_bind; Est1 DNA/RNA binding domain
    pfam10374
    Location:76192
    EST1; Telomerase activating protein Est1
  2. XM_006501343.1XP_006501406.1  

    Conserved Domains (3) summary
    pfam10373
    Location:183397
    EST1_DNA_bind; Est1 DNA/RNA binding domain
    pfam10374
    Location:76178
    EST1; Telomerase activating protein Est1
    cl14812
    Location:8421000
    PIN_SF; PIN (PilT N terminus) domain: Superfamily
  3. XM_006501344.1XP_006501407.1  

    Conserved Domains (3) summary
    pfam10373
    Location:131345
    EST1_DNA_bind; Est1 DNA/RNA binding domain
    pfam10374
    Location:10126
    EST1; Telomerase activating protein Est1
    cl14812
    Location:790948
    PIN_SF; PIN (PilT N terminus) domain: Superfamily
  4. XM_006501345.1XP_006501408.1  

    Conserved Domains (1) summary
    cl14812
    Location:595753
    PIN_SF; PIN (PilT N terminus) domain: Superfamily

Alternate Mm_Celera

Genomic

  1. AC_000025.1 

    Range
    88375893..88401966
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_173188.1: Suppressed sequence

    Description
    NM_173188.1: This RefSeq was temporarily suppressed because the CDS was partial when compared to proteins in other species such as human.