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Gmps guanine monophosphate synthetase [ Mus musculus (house mouse) ]

Gene ID: 229363, updated on 28-May-2016
Official Symbol
Gmpsprovided by MGI
Official Full Name
guanine monophosphate synthetaseprovided by MGI
Primary source
MGI:MGI:2448526
See related
Ensembl:ENSMUSG00000027823 Vega:OTTMUSG00000031018
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
AA591640; AI047208
Orthologs
Location:
3; 3 E1
Exon count:
18
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 3 NC_000069.6 (63964819..64021490)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (63780065..63823000)

Chromosome 3 - NC_000069.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA E130311K13 gene Neighboring gene solute carrier family 33 (acetyl-CoA transporter), member 1 Neighboring gene predicted gene, 40065 Neighboring gene predicted gene, 40188

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
GMP synthase (glutamine-hydrolyzing) activity IBA
Inferred from Biological aspect of Ancestor
more info
 
GMP synthase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
GMP synthase activity ISO
Inferred from Sequence Orthology
more info
 
ligase activity IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
pyrophosphatase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
GMP biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
 
GMP biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
glutamine metabolic process IEA
Inferred from Electronic Annotation
more info
 
purine nucleotide biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 
cytosol ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
GMP synthase [glutamine-hydrolyzing]
Names
GMP synthase
GMP synthetase
glutamine amidotransferase
guanine monophosphate synthetase
NP_001028472.2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033300.2NP_001028472.2  GMP synthase [glutamine-hydrolyzing]

    See identical proteins and their annotated locations for NP_001028472.2

    Status: VALIDATED

    Source sequence(s)
    AK049755, AK136966, AK143197, CN528611
    Consensus CDS
    CCDS17383.1
    UniProtKB/Swiss-Prot
    Q3THK7
    UniProtKB/TrEMBL
    B2RRH9
    Related
    ENSMUSP00000029405, OTTMUSP00000040514, ENSMUST00000029405, OTTMUST00000076838
    Conserved Domains (3) summary
    cd01742
    Location:28207
    GATase1_GMP_Synthase; Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase
    PRK00074
    Location:28693
    guaA; GMP synthase; Reviewed
    cd01997
    Location:238692
    GMP_synthase_C; The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000069.6 Reference GRCm38.p3 C57BL/6J

    Range
    63964819..64021490
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011240078.1XP_011238380.1  

    Conserved Domains (3) summary
    cd01742
    Location:80259
    GATase1_GMP_Synthase; Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase
    PRK00074
    Location:80745
    guaA; GMP synthase; Reviewed
    cd01997
    Location:290744
    GMP_synthase_C; The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched ...

Alternate Mm_Celera

Genomic

  1. AC_000025.1 Alternate Mm_Celera

    Range
    63647946..63691053
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)