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HABP4 hyaluronan binding protein 4 [ Homo sapiens (human) ]

Gene ID: 22927, updated on 5-Jul-2015
Official Symbol
HABP4provided by HGNC
Official Full Name
hyaluronan binding protein 4provided by HGNC
Primary source
HGNC:HGNC:17062
See related
Ensembl:ENSG00000130956; HPRD:13628; Vega:OTTHUMG00000020298
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
IHABP4; IHABP-4; Ki-1/57; SERBP1L
Orthologs
See HABP4 in Epigenomics, MapViewer
Location:
9q22.3-q31
Exon count:
9
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 9 NC_000009.12 (96450155..96491336)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (99212414..99253618)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene hydroxysteroid (17-beta) dehydrogenase 3 Neighboring gene solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2 Neighboring gene NSA2 ribosome biogenesis homolog (S. cerevisiae) pseudogene Neighboring gene zinc finger protein 367 Neighboring gene cell division cycle 14B Neighboring gene uncharacterized LOC105376163 Neighboring gene uncharacterized LOC105376164

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • Hemostasis, organism-specific biosystem (from REACTOME)
    Hemostasis, organism-specific biosystemHemostasis is a physiological response that culminates in the arrest of bleeding from an injured vessel. Under normal conditions the vascular endothelium supports vasodilation, inhibits platelet adhe...
  • Platelet activation, signaling and aggregation, organism-specific biosystem (from REACTOME)
    Platelet activation, signaling and aggregation, organism-specific biosystemPlatelet activation begins with the initial binding of adhesive ligands and of the excitatory platelet agonists (released or generated at the sites of vascular trauma) to cognate receptors on the pla...
  • Platelet degranulation, organism-specific biosystem (from REACTOME)
    Platelet degranulation, organism-specific biosystemPlatelets function as exocytotic cells, secreting a plethora of effector molecules at sites of vascular injury. Platelets contain a number of distinguishable storage granules including alpha granules...
  • Response to elevated platelet cytosolic Ca2+, organism-specific biosystem (from REACTOME)
    Response to elevated platelet cytosolic Ca2+, organism-specific biosystemActivation of phospholipase C enzymes results in the generation of second messengers of the phosphatidylinositol pathway. The events resulting from this pathway are a rise in intracellular calcium an...
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • MGC825

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
blood coagulation TAS
Traceable Author Statement
more info
 
cellular response to mechanical stimulus ISS
Inferred from Sequence or Structural Similarity
more info
 
negative regulation of DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
platelet activation TAS
Traceable Author Statement
more info
 
platelet degranulation TAS
Traceable Author Statement
more info
 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
 
cytoplasm ISS
Inferred from Sequence or Structural Similarity
more info
 
cytosol TAS
Traceable Author Statement
more info
 
extracellular region TAS
Traceable Author Statement
more info
 
nucleoplasm IDA
Inferred from Direct Assay
more info
 
nucleus ISS
Inferred from Sequence or Structural Similarity
more info
 
sarcomere ISS
Inferred from Sequence or Structural Similarity
more info
 
Preferred Names
intracellular hyaluronan-binding protein 4
Names
HABP4
chromodomain helicase DNA binding protein 3 interacting protein
intracellular antigen detected by monoclonal antibody Ki-1
ki-1/57 intracellular antigen

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_014282.3NP_055097.2  intracellular hyaluronan-binding protein 4

    See identical proteins and their annotated locations for NP_055097.2

    Status: VALIDATED

    Source sequence(s)
    AF241831, AK025144, BC018788, CN287447, DR006985, HY139664
    Consensus CDS
    CCDS6719.1
    UniProtKB/Swiss-Prot
    Q5JVS0
    Related
    ENSP00000364398, OTTHUMP00000021722, ENST00000375249, OTTHUMT00000053269
    Conserved Domains (1) summary
    pfam04774
    Location:212317
    HABP4_PAI-RBP1; Hyaluronan / mRNA binding family

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p2 Primary Assembly

    Range
    96450155..96491336
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005251812.2XP_005251869.1  

    Conserved Domains (1) summary
    pfam04774
    Location:102207
    HABP4_PAI-RBP1; Hyaluronan / mRNA binding family

Alternate CHM1_1.1

Genomic

  1. NC_018920.2 Alternate CHM1_1.1

    Range
    99359280..99400445
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)