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WDR47 WD repeat domain 47 [ Homo sapiens (human) ]

Gene ID: 22911, updated on 8-May-2016
Official Symbol
WDR47provided by HGNC
Official Full Name
WD repeat domain 47provided by HGNC
Primary source
HGNC:HGNC:29141
See related
Ensembl:ENSG00000085433 HPRD:15670; MIM:615734; Vega:OTTHUMG00000011734
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Orthologs
Location:
1p13.3
Exon count:
16
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 1 NC_000001.11 (108970211..109042228, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (109512835..109584860, complement)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene AKNA domain containing 1 Neighboring gene spermatogenesis associated 42 (non-protein coding) Neighboring gene G-protein signaling modulator 2 Neighboring gene chloride channel CLIC like 1 Neighboring gene ribosomal protein L17 pseudogene 7 Neighboring gene ribosomal protein S27 pseudogene 6 Neighboring gene RAN, member RAS oncogene family pseudogene 5 Neighboring gene TATA-box binding protein associated factor 13

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • FLJ90135, KIAA0893

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
multicellular organism development IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
microtubule IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
WD repeat-containing protein 47
Names
nemitin
neuronal enriched MAP interacting protein
neuronal enriched MAP-interacting protein

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001142550.1NP_001136022.1  WD repeat-containing protein 47 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    AK225781, BM793705, DA221069
    Consensus CDS
    CCDS44186.1
    UniProtKB/Swiss-Prot
    O94967
    Related
    ENSP00000383599, OTTHUMP00000233693, ENST00000400794, OTTHUMT00000390717
    Conserved Domains (4) summary
    smart00667
    Location:942
    LisH; Lissencephaly type-1-like homology motif
    smart00668
    Location:45102
    CTLH; C-terminal to LisH motif
    COG2319
    Location:553926
    WD40; WD40 repeat [General function prediction only]
    cd00200
    Location:614923
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  2. NM_001142551.1NP_001136023.1  WD repeat-containing protein 47 isoform 3

    See identical proteins and their annotated locations for NP_001136023.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) uses several alternate in-frame splice sites in the 5' coding region, compared to variant 1, resulting in a protein (isoform 3) with a shorter N-terminus, compared to isoform 1.
    Source sequence(s)
    AB020700, AK225781, BC039254, BM793705, DA221069
    Consensus CDS
    CCDS44187.1
    UniProtKB/Swiss-Prot
    O94967
    Related
    ENSP00000358979, OTTHUMP00000013444, ENST00000369962, OTTHUMT00000032414
    Conserved Domains (4) summary
    smart00667
    Location:942
    LisH; Lissencephaly type-1-like homology motif
    smart00668
    Location:45102
    CTLH; C-terminal to LisH motif
    COG2319
    Location:545918
    WD40; WD40 repeat [General function prediction only]
    cd00200
    Location:606915
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  3. NM_014969.5NP_055784.3  WD repeat-containing protein 47 isoform 2

    See identical proteins and their annotated locations for NP_055784.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 5' coding region, compared to variant 1, resulting in a protein (isoform 2) with a shorter N-terminus, compared to isoform 1.
    Source sequence(s)
    AK225781, AK289789, BM793705, DA221069
    Consensus CDS
    CCDS30787.1
    UniProtKB/Swiss-Prot
    O94967
    Related
    ENSP00000358982, OTTHUMP00000013443, ENST00000369965, OTTHUMT00000032413
    Conserved Domains (4) summary
    smart00667
    Location:942
    LisH; Lissencephaly type-1-like homology motif
    smart00668
    Location:45102
    CTLH; C-terminal to LisH motif
    COG2319
    Location:546919
    WD40; WD40 repeat [General function prediction only]
    cd00200
    Location:607916
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p2 Primary Assembly

    Range
    108970211..109042228 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011541029.1XP_011539331.1  

    Conserved Domains (4) summary
    smart00667
    Location:942
    LisH; Lissencephaly type-1-like homology motif
    smart00668
    Location:45102
    CTLH; C-terminal to LisH motif
    COG2319
    Location:553928
    WD40; WD40 repeat [General function prediction only]
    cd00200
    Location:614925
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  2. XM_006710460.2XP_006710523.1  

    See identical proteins and their annotated locations for XP_006710523.1

    Related
    ENSP00000350301, ENST00000357672
    Conserved Domains (4) summary
    smart00667
    Location:942
    LisH; Lissencephaly type-1-like homology motif
    smart00668
    Location:45102
    CTLH; C-terminal to LisH motif
    COG2319
    Location:546921
    WD40; WD40 repeat [General function prediction only]
    cd00200
    Location:607918
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  3. XM_011541030.1XP_011539332.1  

    See identical proteins and their annotated locations for XP_011539332.1

    Conserved Domains (4) summary
    smart00667
    Location:942
    LisH; Lissencephaly type-1-like homology motif
    smart00668
    Location:45102
    CTLH; C-terminal to LisH motif
    COG2319
    Location:546921
    WD40; WD40 repeat [General function prediction only]
    cd00200
    Location:607918
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  4. XM_011541028.1XP_011539330.1  

    See identical proteins and their annotated locations for XP_011539330.1

    Conserved Domains (4) summary
    smart00667
    Location:942
    LisH; Lissencephaly type-1-like homology motif
    smart00668
    Location:45102
    CTLH; C-terminal to LisH motif
    COG2319
    Location:545920
    WD40; WD40 repeat [General function prediction only]
    cd00200
    Location:606917
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  5. XM_011541027.1XP_011539329.1  

    Conserved Domains (4) summary
    smart00667
    Location:942
    LisH; Lissencephaly type-1-like homology motif
    smart00668
    Location:45102
    CTLH; C-terminal to LisH motif
    COG2319
    Location:552927
    WD40; WD40 repeat [General function prediction only]
    cd00200
    Location:613924
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  6. XM_011541031.1XP_011539333.1  

    Conserved Domains (2) summary
    COG2319
    Location:453828
    WD40; WD40 repeat [General function prediction only]
    cd00200
    Location:514825
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

Alternate CHM1_1.1

Genomic

  1. NC_018912.2 Alternate CHM1_1.1

    Range
    109627778..109697851 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)