Display Settings:

Format

Send to:

Choose Destination

    CLSTN1 calsyntenin 1 [ Homo sapiens ]

    Gene ID: 22883, updated on 9-Feb-2012

    Summary

    Official Symbol
    CLSTN1provided by HGNC
    Official Full Name
    calsyntenin 1provided by HGNC
    Primary source
    HGNC:17447
    Locus tag
    RP11-558F24.5
    See related
    Ensembl:ENSG00000171603; HPRD:10837; MIM:611321; Vega:OTTHUMG00000001451
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    CSTN1; CDHR12; PIK3CD; ALC-ALPHA; XB31alpha; alcalpha1; alcalpha2

    Genomic context

    Location :
    1p36.22
    Sequence :
    Chromosome: 1; NC_000001.10 (9789079..9884550, complement)
    See CLSTN1 in Epigenomics, MapViewer

    Chromosome 1 - NC_000001.10Genomic Context describing neighboring genes Neighboring gene chromosome 1 open reading frame 200 Neighboring gene phosphoinositide-3-kinase, catalytic, delta polypeptide Neighboring gene ribosomal protein L26 pseudogene 7 Neighboring gene uncharacterized LOC645010 Neighboring gene catenin, beta interacting protein 1

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    O94985 Q99767 APBA2    HPRD  PubMed  
    O94985 O00213 APBB1    HPRD  PubMed  
    O94985 BAH domain and coiled-coil containing 1 BAHCC1    HPRD  PubMed  
    O94985 O94985 CLSTN1    HPRD  PubMed  
    O94985 Q9UMD9 COL17A1    HPRD  PubMed  
    O94985 O00139 KIF2A    HPRD  PubMed  
    O94985 Q07866 KLC1    HPRD  PubMed  
    O94985 Q9H0B6 KLC2    HPRD  PubMed  
    O94985 O60318 MCM3AP    HPRD  PubMed  
    O94985 P04156 PRNP    HPRD  PubMed  
    O94985 Q15047 SETDB1    HPRD  PubMed  
    O94985 Q9H2G2 SLK    HPRD  PubMed  
    O94985 Q92547 TOPBP1    HPRD  PubMed  
    O94985 Q14669 TRIP12    HPRD  PubMed  
    BioGRID:116550 BioGRID:106818 APBA2    BioGRID  PubMed Affinity Capture-Western; Two-hybrid 
    BioGRID:116550 BioGRID:106848 APP    BioGRID  PubMed Affinity Capture-Western 
    BioGRID:116550 BioGRID:111642 PSEN1    BioGRID  PubMed Affinity Capture-Western 

    General gene information

    Markers

    Homology

    Clone Names

    • FLJ32258, KIAA0911

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    cell adhesion IEA
    Inferred from Electronic Annotation
    more info
     
    homophilic cell adhesion IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
     
    Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
     
    cell junction IEA
    Inferred from Electronic Annotation
    more info
     
    cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
     
    extracellular region IEA
    Inferred from Electronic Annotation
    more info
     
    integral to membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    postsynaptic membrane IEA
    Inferred from Electronic Annotation
    more info
     
    synapse IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    calsyntenin-1
    Names
    calsyntenin-1
    alcadein-alpha
    alcadein alpha 1
    non-classical cadherin XB31alpha
    cadherin-related family member 12
    non-classical cadherin XB31alpha1
    alzheimer-related cadherin-like protein

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001009566.1NP_001009566.1  calsyntenin-1 isoform 1 precursor

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AB020718, CB132727
      Consensus CDS
      CCDS30580.1
      UniProtKB/Swiss-Prot
      O94985
      Related
      ENSP00000366513, OTTHUMP00000001597, ENST00000377298, OTTHUMT00000004239
      Conserved Domains (2) summary
      cd11304
      Location:168258
      Blast Score: 138
      Cadherin_repeat; Cadherin tandem repeat domain.
      cl00102
      Location:362510
      Blast Score: 127
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    2. NM_014944.3NP_055759.3  calsyntenin-1 isoform 2 precursor

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks in alternate in-frame exon, compared to variant 1, resulting in a shorter isoform (2) that is missing an internal segment compared to isoform 1.
      Source sequence(s)
      AF438482, AK001591, BC033902, CB132727
      Consensus CDS
      CCDS105.1
      UniProtKB/TrEMBL
      B3KMD3
      UniProtKB/Swiss-Prot
      O94985
      Related
      ENSP00000354997, OTTHUMP00000001598, ENST00000361311, OTTHUMT00000004240
      Conserved Domains (2) summary
      cd11304
      Location:41149
      Blast Score: 144
      Cadherin_repeat; Cadherin tandem repeat domain.
      cl00102
      Location:352500
      Blast Score: 127
      LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...

    RefSeqs of Annotated Genomes: Build 37.3

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh37.p5 Primary Assembly

    Genomic

    1. NC_000001.10 Reference GRCh37.p5 Primary Assembly

      Range
      9789079..9884550, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate HuRef

    Genomic

    1. AC_000133.1 Alternate HuRef

      Range
      8945184..9040629, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

      Supplemental Content

      Recent activity

      Your browsing activity is empty.

      Activity recording is turned off.

      Turn recording back on

      See more...