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Ikzf4 IKAROS family zinc finger 4 [ Mus musculus (house mouse) ]

Gene ID: 22781, updated on 8-May-2016
Official Symbol
Ikzf4provided by MGI
Official Full Name
IKAROS family zinc finger 4provided by MGI
Primary source
MGI:MGI:1343139
See related
Ensembl:ENSMUSG00000002578 Vega:OTTMUSG00000025110
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Eos; Zfpn1a4; Znfn1a4; A630026H08Rik
Orthologs
Location:
10; 10 D3
Exon count:
12
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 10 NC_000076.6 (128630839..128669358, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (128069471..128083049, complement)

Chromosome 10 - NC_000076.6Genomic Context describing neighboring genes Neighboring gene predicted gene 9182 Neighboring gene ribosomal protein S26 Neighboring gene predicted gene, 26876 Neighboring gene predicted gene, 40807 Neighboring gene sulfite oxidase Neighboring gene ribosomal protein L12 pseudogene

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
bHLH transcription factor binding IPI
Inferred from Physical Interaction
more info
PubMed 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein heterodimerization activity IPI
Inferred from Physical Interaction
more info
PubMed 
protein homodimerization activity IPI
Inferred from Physical Interaction
more info
PubMed 
sequence-specific DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
transcription factor activity, sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
transcription regulatory region DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
negative regulation of transcription, DNA-templated IPI
Inferred from Physical Interaction
more info
PubMed 
positive regulation of transcription from RNA polymerase II promoter IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
centrosome ISO
Inferred from Sequence Orthology
more info
 
nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
nucleus IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
zinc finger protein Eos
Names
ikaros family zinc finger protein 4
zinc finger protein, subfamily 1A, 4 (Eos)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_011772.2NP_035902.2  zinc finger protein Eos

    See identical proteins and their annotated locations for NP_035902.2

    Status: VALIDATED

    Source sequence(s)
    AC117232, AK089522
    Consensus CDS
    CCDS24284.2
    UniProtKB/Swiss-Prot
    Q8C208
    Related
    ENSMUSP00000114404, OTTMUSP00000030370, ENSMUST00000133342, OTTMUST00000061771
    Conserved Domains (2) summary
    pfam13465
    Location:174198
    zf-H2C2_2; Zinc-finger double domain
    sd00017
    Location:161181
    ZF_C2H2; C2H2 Zn finger [structural motif]

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000076.6 Reference GRCm38.p3 C57BL/6J

    Range
    128630839..128669358 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006513613.2XP_006513676.1  

    See identical proteins and their annotated locations for XP_006513676.1

    Conserved Domains (2) summary
    pfam13465
    Location:127151
    zf-H2C2_2; Zinc-finger double domain
    sd00017
    Location:114134
    ZF_C2H2; C2H2 Zn finger [structural motif]
  2. XM_011243441.1XP_011241743.1  

    See identical proteins and their annotated locations for XP_011241743.1

    Conserved Domains (2) summary
    pfam13465
    Location:127151
    zf-H2C2_2; Zinc-finger double domain
    sd00017
    Location:114134
    ZF_C2H2; C2H2 Zn finger [structural motif]
  3. XM_006513614.1XP_006513677.1  

    See identical proteins and their annotated locations for XP_006513677.1

    UniProtKB/Swiss-Prot
    Q8C208
    Conserved Domains (2) summary
    pfam13465
    Location:119143
    zf-H2C2_2; Zinc-finger double domain
    sd00017
    Location:106126
    ZF_C2H2; C2H2 Zn finger [structural motif]
  4. XM_011243442.1XP_011241744.1  

    See identical proteins and their annotated locations for XP_011241744.1

    UniProtKB/Swiss-Prot
    Q8C208
    Related
    ENSMUSP00000113478, OTTMUSP00000038694, ENSMUST00000119614, OTTMUST00000074374
    Conserved Domains (2) summary
    pfam13465
    Location:121145
    zf-H2C2_2; Zinc-finger double domain
    sd00017
    Location:108128
    ZF_C2H2; C2H2 Zn finger [structural motif]
  5. XM_006513615.1XP_006513678.1  

    See identical proteins and their annotated locations for XP_006513678.1

    UniProtKB/Swiss-Prot
    Q8C208
    Conserved Domains (2) summary
    pfam13465
    Location:119143
    zf-H2C2_2; Zinc-finger double domain
    sd00017
    Location:106126
    ZF_C2H2; C2H2 Zn finger [structural motif]
  6. XM_011243440.1XP_011241742.1  

    See identical proteins and their annotated locations for XP_011241742.1

    Conserved Domains (2) summary
    pfam13465
    Location:129153
    zf-H2C2_2; Zinc-finger double domain
    sd00017
    Location:116136
    ZF_C2H2; C2H2 Zn finger [structural motif]
  7. XM_006513612.1XP_006513675.1  

    See identical proteins and their annotated locations for XP_006513675.1

    Conserved Domains (2) summary
    pfam13465
    Location:129153
    zf-H2C2_2; Zinc-finger double domain
    sd00017
    Location:116136
    ZF_C2H2; C2H2 Zn finger [structural motif]
  8. XM_006513616.1XP_006513679.1  

    Conserved Domains (3) summary
    COG5048
    Location:83140
    COG5048; FOG: Zn-finger [General function prediction only]
    pfam13465
    Location:99124
    zf-H2C2_2; Zinc-finger double domain
    sd00017
    Location:5979
    ZF_C2H2; C2H2 Zn finger [structural motif]

Alternate Mm_Celera

Genomic

  1. AC_000032.1 Alternate Mm_Celera

    Range
    131024505..131038081 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)