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Zhx1 zinc fingers and homeoboxes 1 [ Mus musculus (house mouse) ]

Gene ID: 22770, updated on 8-May-2016
Official Symbol
Zhx1provided by MGI
Official Full Name
zinc fingers and homeoboxes 1provided by MGI
Primary source
MGI:MGI:109271
See related
Ensembl:ENSMUSG00000022361 Vega:OTTMUSG00000041982
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Orthologs
Location:
15; 15 D2
Exon count:
5
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 15 NC_000081.6 (58047003..58076508, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (57878558..57908044, complement)

Chromosome 15 - NC_000081.6Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 83, member A Neighboring gene RIKEN cDNA 9130401M01 gene Neighboring gene ATPase family, AAA domain containing 2 Neighboring gene small nuclear ribonucleoprotein Sm D2 pseudogene Neighboring gene WDYHV motif containing 1

Markers

Homology

Clone Names

  • KIAA4149, mKIAA4149, 3110006I21Rik

Gene Ontology Provided by MGI

Function Evidence Code Pubs
DNA binding ISO
Inferred from Sequence Orthology
more info
 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
protein heterodimerization activity ISO
Inferred from Sequence Orthology
more info
 
transcription corepressor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
transcription corepressor activity ISO
Inferred from Sequence Orthology
more info
 
transcription factor activity, sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
transcription factor activity, sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
negative regulation of transcription from RNA polymerase II promoter IBA
Inferred from Biological aspect of Ancestor
more info
 
negative regulation of transcription from RNA polymerase II promoter ISO
Inferred from Sequence Orthology
more info
 
negative regulation of transcription, DNA-templated ISO
Inferred from Sequence Orthology
more info
 
regulation of transcription, DNA-templated ISO
Inferred from Sequence Orthology
more info
 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
zinc fingers and homeoboxes protein 1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001042438.2NP_001035903.1  zinc fingers and homeoboxes protein 1

    See identical proteins and their annotated locations for NP_001035903.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) represents the longer transcript. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC113292, AK220508, BC054543, CJ093421, CN533009
    Consensus CDS
    CCDS27488.1
    UniProtKB/Swiss-Prot
    P70121
    UniProtKB/TrEMBL
    Q5DTL2
    Related
    ENSMUSP00000105797, ENSMUST00000110168
    Conserved Domains (1) summary
    cd00086
    Location:468523
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.
  2. NM_009572.4NP_033598.2  zinc fingers and homeoboxes protein 1

    See identical proteins and their annotated locations for NP_033598.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) differs in the 5' UTR, compared to variant 2. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC113292, AK220508, BC054543, CJ093421
    Consensus CDS
    CCDS27488.1
    UniProtKB/Swiss-Prot
    P70121
    UniProtKB/TrEMBL
    Q5DTL2
    Related
    ENSMUSP00000066201, OTTMUSP00000061251, ENSMUST00000070143, OTTMUST00000109937
    Conserved Domains (1) summary
    cd00086
    Location:468523
    homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000081.6 Reference GRCm38.p3 C57BL/6J

    Range
    58047003..58076508 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000037.1 Alternate Mm_Celera

    Range
    59567020..59596528 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)