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    Tubb4b tubulin, beta 4B class IVB [ Mus musculus ]

    Gene ID: 227613, updated on 11-May-2012

    Summary

    Official Symbol
    Tubb4bprovided by MGI
    Official Full Name
    tubulin, beta 4B class IVBprovided by MGI
    Primary source
    MGI:1915472
    Locus tag
    RP23-132N23.7
    See related
    Ensembl:ENSMUSG00000036752; Vega:OTTMUSG00000011806
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Tubb2c; Tubb2c1; MGC6713; 4930542G03Rik; MGC28623; RP23-132N23.7; MGC101937

    Genomic context

    Location :
    2 A3; 2
    Sequence :
    Chromosome: 2; NC_000068.7 (25222158..25224702, complement)
    See Tubb4b in Epigenomics, MapViewer

    Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene cofactor of BRCA1 Neighboring gene RIKEN cDNA 4933433C11 gene Neighboring gene family with sequence similarity 166, member A Neighboring gene solute carrier family 34 (sodium phosphate), member 3 Neighboring gene predicted gene 757

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    BioGRID:230642 BioGRID:114579 AIFM1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:230642 BioGRID:106895 ARL2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:230642 BioGRID:107147 BSG    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:230642 BioGRID:122716 C2orf47    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:230642 BioGRID:126282 CHCHD4    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:230642 BioGRID:107917 CYC1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:230642 BioGRID:109534 DNAJA1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:230642 BioGRID:115582 DNAJA2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:230642 BioGRID:108486 FBLN1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:230642 BioGRID:109610 ICAM1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:230642 BioGRID:120825 MAP7D1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:230642 BioGRID:110415 MGST3    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:230642 BioGRID:201639 Myd88    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:230642 BioGRID:111223 PFDN1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:230642 BioGRID:111224 PFDN2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:230642 BioGRID:111226 PFDN5    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:230642 BioGRID:115734 PFDN6    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:230642 BioGRID:117618 PHGDH    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:230642 BioGRID:116480 RRAS2    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:230642 BioGRID:112767 TBCD    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:230642 BioGRID:124961 TIMM50    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:230642 BioGRID:113254 VBP1    BioGRID  PubMed Affinity Capture-MS 
    BioGRID:230642 BioGRID:113262 VDAC3    BioGRID  PubMed Affinity Capture-MS 

    General gene information

    Markers

    Homology

    • Homologs of the Tubb4b gene: The Tubb4b gene is conserved in human, chimpanzee, , dog, cow, rat, chicken, zebrafish, fruit fly, mosquito, C.elegans, S.cerevisiae, K.lactis, , S.pombe, , N.crassa, and A.thaliana.
    • Map Viewer (Human, Rat)

    Pathways from BioSystems

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    GTP binding NAS
    Non-traceable Author Statement
    more info
    PubMed 
    GTPase activity IEA
    Inferred from Electronic Annotation
    more info
     
    nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    structural molecule activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    GTP catabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    microtubule-based movement IEA
    Inferred from Electronic Annotation
    more info
     
    microtubule-based process NAS
    Non-traceable Author Statement
    more info
    PubMed 
    protein polymerization IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    microtubule IEA
    Inferred from Electronic Annotation
    more info
     
    protein complex IEA
    Inferred from Electronic Annotation
    more info
     
    tubulin complex NAS
    Non-traceable Author Statement
    more info
    PubMed 

    General protein information

    Preferred Names
    tubulin beta-4B chain
    Names
    tubulin beta-4B chain
    tubulin, beta 2C
    tubulin, beta, 2
    tubulin, beta 2c1
    novel tubulin protein
    tubulin beta-2C chain

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_146116.2NP_666228.1  tubulin beta-4B chain

      Status: VALIDATED

      Source sequence(s)
      AK167022, AL732309, CJ309661
      Consensus CDS
      CCDS15753.1
      UniProtKB/Swiss-Prot
      P68372
      Related
      ENSMUSP00000042342, OTTMUSP00000012597, ENSMUST00000043584, OTTMUST00000027720
      Conserved Domains (2) summary
      cd02187
      Location:2426
      Blast Score: 2460
      beta_tubulin; The tubulin superfamily includes five distinct families, the alpha-, beta-, gamma-, delta-, and epsilon-tubulins and a sixth family (zeta-tubulin) which is present only in kinetoplastid protozoa. The alpha- and beta-tubulins are the major components of ...
      PLN00220
      Location:1427
      Blast Score: 2371
      PLN00220; tubulin beta chain; Provisional

    RefSeqs of Annotated Genomes: Build 38.1

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38 C57BL/6J

    Genomic

    1. NC_000068.7 Reference GRCm38 C57BL/6J

      Range
      25222158..25224702, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Mm_Celera

    Genomic

    1. AC_000024.1 Alternate Mm_Celera

      Range
      24949941..24952486, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Related Sequences

    Nucleotide Protein Strain
    Heading Accession and Version
    genomic AL732309.9 CAM14671.1
    mRNA AK002568.1 BAB22193.2 C57BL/6J
    mRNA AK006924.1 BAB24792.2 C57BL/6J
    mRNA AK015901.1 None C57BL/6J
    mRNA AK076895.1 None C57BL/6J
    mRNA AK146587.1 BAE27282.1
    mRNA AK167022.1 BAE39195.1 C57BL/6J
    mRNA AK194925.1 None
    mRNA AK195017.1 None
    mRNA AK214079.1 None
    mRNA BC005547.1 AAH05547.1 FVB/N
    mRNA BC022919.1 AAH22919.1 FVB/N
    mRNA BC083319.1 AAH83319.1 C57BL/6
    mRNA CJ309661.1 None
    Protein Accession Links
    GenPept Link UniProtKB Link
    P68372.1 GenPept UniProtKB/Swiss-Prot:P68372
    Q9CVR0 GenPept UniProtKB/TrEMBL:Q9CVR0
    Q9DCR1 GenPept UniProtKB/TrEMBL:Q9DCR1

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