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Atf6 activating transcription factor 6 [ Mus musculus (house mouse) ]

Gene ID: 226641, updated on 8-May-2016
Official Symbol
Atf6provided by MGI
Official Full Name
activating transcription factor 6provided by MGI
Primary source
MGI:MGI:1926157
See related
Ensembl:ENSMUSG00000026663 Vega:OTTMUSG00000043564
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
ESTM49; AA789574; Atf6alpha; 9630036G24; 9130025P16Rik
Orthologs
Location:
1 H3; 1 76.96 cM
Exon count:
17
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 1 NC_000067.6 (170704457..170867771, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (172634588..172797902, complement)

Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene ribosomal protein L17 pseudogene Neighboring gene olfactomedin-like 2B Neighboring gene predicted gene, 29733 Neighboring gene dual specificity phosphatase 12 Neighboring gene Fc receptor-like B

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
RNA polymerase II regulatory region sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
cAMP response element binding IEA
Inferred from Electronic Annotation
more info
 
identical protein binding ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein heterodimerization activity ISO
Inferred from Sequence Orthology
more info
 
sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 
transcription factor activity, sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
transcription regulatory region sequence-specific DNA binding ISO
Inferred from Sequence Orthology
more info
 
ubiquitin protein ligase binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
endoplasmic reticulum unfolded protein response IEA
Inferred from Electronic Annotation
more info
 
eye development ISO
Inferred from Sequence Orthology
more info
 
positive regulation of transcription from RNA polymerase II promoter IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress ISO
Inferred from Sequence Orthology
more info
 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
response to unfolded protein IEA
Inferred from Electronic Annotation
more info
 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
visual perception ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
endoplasmic reticulum NAS
Non-traceable Author Statement
more info
PubMed 
endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of endoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane ISO
Inferred from Sequence Orthology
more info
 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus ISO
Inferred from Sequence Orthology
more info
 
nucleus NAS
Non-traceable Author Statement
more info
PubMed 
Preferred Names
cyclic AMP-dependent transcription factor ATF-6 alpha
Names
ATF6-alpha
activating transcription factor 6 alpha
cAMP-dependent transcription factor ATF-6 alpha

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001081304.1NP_001074773.1  cyclic AMP-dependent transcription factor ATF-6 alpha

    See identical proteins and their annotated locations for NP_001074773.1

    Status: VALIDATED

    Source sequence(s)
    AC113490, AC125021
    Consensus CDS
    CCDS56653.1
    UniProtKB/Swiss-Prot
    F6VAN0
    Related
    ENSMUSP00000027974, OTTMUSP00000063822, ENSMUST00000027974, OTTMUST00000114360
    Conserved Domains (1) summary
    cd14700
    Location:296347
    bZIP_ATF6; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-6 (ATF-6) and similar proteins: a DNA-binding and dimerization domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000067.6 Reference GRCm38.p3 C57BL/6J

    Range
    170704457..170867771 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011238796.1XP_011237098.1  

    Conserved Domains (1) summary
    cd14700
    Location:296347
    bZIP_ATF6; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-6 (ATF-6) and similar proteins: a DNA-binding and dimerization domain
  2. XM_006496792.2XP_006496855.1  

    Conserved Domains (1) summary
    cd14700
    Location:281332
    bZIP_ATF6; Basic leucine zipper (bZIP) domain of Activating Transcription Factor-6 (ATF-6) and similar proteins: a DNA-binding and dimerization domain

Alternate Mm_Celera

Genomic

  1. AC_000023.1 Alternate Mm_Celera

    Range
    173146825..173324073 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)