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Dars2 aspartyl-tRNA synthetase 2 (mitochondrial) [ Mus musculus (house mouse) ]

Gene ID: 226539, updated on 17-Mar-2015
Official Symbol
Dars2provided by MGI
Official Full Name
aspartyl-tRNA synthetase 2 (mitochondrial)provided by MGI
Primary source
MGI:MGI:2442510
See related
Ensembl:ENSMUSG00000026709; Vega:OTTMUSG00000031015
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
5830468K18Rik
Orthologs
See Dars2 in MapViewer
Location:
1; 1 H2.1
Exon count:
17
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 1 NC_000067.6 (161040612..161070658, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (162970744..163000763, complement)

Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene zinc finger and BTB domain containing 37 Neighboring gene small nucleolar RNA, C/D box 47 Neighboring gene growth arrest specific 5 Neighboring gene centromere protein L Neighboring gene kelch-like 20

Markers

Homology

Clone Names

  • MGC99963

Gene Ontology Provided by MGI

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
aminoacyl-tRNA ligase activity IEA
Inferred from Electronic Annotation
more info
 
aspartate-tRNA ligase activity IEA
Inferred from Electronic Annotation
more info
 
aspartate-tRNA(Asn) ligase activity ISO
Inferred from Sequence Orthology
more info
 
ligase activity IEA
Inferred from Electronic Annotation
more info
 
nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
protein homodimerization activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
tRNA aminoacylation ISO
Inferred from Sequence Orthology
more info
 
tRNA aminoacylation for protein translation IEA
Inferred from Electronic Annotation
more info
 
translation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion ISO
Inferred from Sequence Orthology
more info
 
nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
nucleus ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
aspartate--tRNA ligase, mitochondrial
Names
aspartate--tRNA ligase, mitochondrial
aspRS
aspartyl-tRNA synthetase, mitochondrial
NP_766232.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_172644.3NP_766232.1  aspartate--tRNA ligase, mitochondrial precursor

    See proteins identical to NP_766232.1

    Status: PROVISIONAL

    Source sequence(s)
    AK138809
    Consensus CDS
    CCDS15413.1
    UniProtKB/Swiss-Prot
    Q8BIP0
    Related
    ENSMUSP00000041851, OTTMUSP00000040500, ENSMUST00000035430, OTTMUST00000076822
    Conserved Domains (4) summary
    PRK00476
    Location:49636
    aspS; aspartyl-tRNA synthetase; Validated
    cd00777
    Location:186606
    AspRS_core; Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of ...
    cd04317
    Location:49182
    EcAspRS_like_N; EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND) ...
    cl22452
    Location:356451
    GAD; GAD domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000067.6 Reference GRCm38.p3 C57BL/6J

    Range
    161040612..161070658
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006496757.1XP_006496820.1  

    Conserved Domains (4) summary
    PRK00476
    Location:49615
    aspS; aspartyl-tRNA synthetase; Validated
    cd00777
    Location:186585
    AspRS_core; Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of ...
    cd04317
    Location:49182
    EcAspRS_like_N; EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND) ...
    cl22452
    Location:356430
    GAD; GAD domain
  2. XM_006496758.2XP_006496821.1  

    Conserved Domains (4) summary
    cd00777
    Location:54474
    AspRS_core; Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of ...
    pfam00152
    Location:34473
    tRNA-synt_2; tRNA synthetases class II (D, K and N)
    cl09930
    Location:150
    RPA_2b-aaRSs_OBF_like; Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold.
    cl22452
    Location:224319
    GAD; GAD domain

Alternate Mm_Celera

Genomic

  1. AC_000023.1 Alternate Mm_Celera

    Range
    163482244..163511984
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)