Mkrn3 makorin, ring finger protein, 3 [Mus musculus] - Gene

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Summary

Official Symbol: Mkrn3provided by MGI
Official Full Name: makorin, ring finger protein, 3provided by MGI
Primary source: MGI:2181178
See related: Ensembl:ENSMUSG00000070527
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Zfp127; D7H15S9-1

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Genomic context

Location :: 7 C; 7 29.0 cM

Sequence :: Chromosome: 7; NC_000073.6 (62417593..62420139, complement)

See Mkrn3 in Epigenomics, MapViewer

Chromosome 7 - NC_000073.6 Genomic Context describing neighboring genes

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Genomic regions, transcripts, and products

Genomic Sequence

Go to nucleotideGraphics FASTA GenBank

Go to reference sequence details

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Bibliography

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Mkrn3, encoding a RING zinc-finger protein, is imprinted, with preferential expression from the paternal allele.
Title: Imprinting of a RING zinc-finger encoding gene in the mouse chromosome region homologous to the Prader-Willi syndrome genetic region.

Submit: New GeneRIF Correction

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Function	Evidence Code	Pubs
ligase activity	IEA Inferred from Electronic Annotation more info
metal ion binding	IEA Inferred from Electronic Annotation more info
nucleic acid binding	IEA Inferred from Electronic Annotation more info
zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
metabolic process	IEA Inferred from Electronic Annotation more info

General protein information

Preferred Names: probable E3 ubiquitin-protein ligase makorin-3

Names: probable E3 ubiquitin-protein ligase makorin-3; zinc finger protein 127

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NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_011746.2 → NP_035876.2 probable E3 ubiquitin-protein ligase makorin-3

Status: PROVISIONAL

Source sequence(s)

BC054771

Consensus CDS

CCDS21327.1

UniProtKB/Swiss-Prot

Q60764

Related

ENSMUSP00000091898, ENSMUST00000094340

Conserved Domains (3) summary

cd00162
Location:347 – 401
Blast Score: 97

RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...

PHA03096
Location:288 – 436
Blast Score: 205

PHA03096; p28-like protein; Provisional

cl11592
Location:92 – 118
Blast Score: 97

zf-CCCH; Zinc finger C-x8-C-x5-C-x3-H type (and similar)

RefSeqs of Annotated Genomes: Build 38.1

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38 C57BL/6J

Genomic

NC_000073.6 Reference GRCm38 C57BL/6J

Range

62417593..62420139, complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

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Related Sequences

Nucleotide		Protein	Strain
Heading	Accession and Version	Protein	Strain
genomic	AC156555.8 (235329..237875)	None
genomic	U19106.1	AAA76863.1
mRNA	AK134870.1	BAE22320.1	C57BL/6J
mRNA	BC054771.1	AAH54771.1	C57BL/6