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Apbb3 amyloid beta (A4) precursor protein-binding, family B, member 3 [ Mus musculus (house mouse) ]

Gene ID: 225372, updated on 28-May-2016
Official Symbol
Apbb3provided by MGI
Official Full Name
amyloid beta (A4) precursor protein-binding, family B, member 3provided by MGI
Primary source
MGI:MGI:108404
See related
Ensembl:ENSMUSG00000006050
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
TR2S; Rirl2; Fe65l2
Orthologs
Location:
18; 18 B2
Exon count:
13
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 18 NC_000084.6 (36671154..36679366, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 18 NC_000084.5 (36830813..36839020, complement)

Chromosome 18 - NC_000084.6Genomic Context describing neighboring genes Neighboring gene eukaryotic translation initiation factor 4E binding protein 3 Neighboring gene steroid receptor RNA activator 1 Neighboring gene Riken cDNA E230025N22 gene Neighboring gene solute carrier family 35, member A4 Neighboring gene predicted gene, 41699

Markers

Homology

Clone Names

  • MGC38710

Gene Ontology Provided by MGI

Function Evidence Code Pubs
beta-amyloid binding IBA
Inferred from Biological aspect of Ancestor
more info
 
beta-amyloid binding ISO
Inferred from Sequence Orthology
more info
 
transcription factor binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
negative regulation of apoptotic process TAS
Traceable Author Statement
more info
PubMed 
regulation of transcription, DNA-templated IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
actin cytoskeleton ISO
Inferred from Sequence Orthology
more info
 
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
Preferred Names
amyloid beta A4 precursor protein-binding family B member 3

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_146085.1NP_666197.1  amyloid beta A4 precursor protein-binding family B member 3

    See identical proteins and their annotated locations for NP_666197.1

    Status: PROVISIONAL

    Source sequence(s)
    BC024809
    Consensus CDS
    CCDS29157.1
    UniProtKB/Swiss-Prot
    Q8R1C9
    UniProtKB/TrEMBL
    Q3UR23
    Related
    ENSMUSP00000001415, ENSMUST00000001415
    Conserved Domains (3) summary
    cd00201
    Location:3261
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd01271
    Location:283413
    PTB2_Fe65; Fe65 C-terminal Phosphotyrosine-binding (PTB) domain
    cd01272
    Location:116254
    PTB1_Fe65; Fe65 N-terminal Phosphotyrosine-binding (PTB) domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000084.6 Reference GRCm38.p3 C57BL/6J

    Range
    36671154..36679366 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006525861.1XP_006525924.1  

    Conserved Domains (3) summary
    cd00201
    Location:3261
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd01271
    Location:284414
    PTB2_Fe65; Fe65 C-terminal Phosphotyrosine-binding (PTB) domain
    cd01272
    Location:116255
    PTB1_Fe65; Fe65 N-terminal Phosphotyrosine-binding (PTB) domain
  2. XM_011246900.1XP_011245202.1  

    Conserved Domains (3) summary
    cd00201
    Location:3261
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    cd01272
    Location:116255
    PTB1_Fe65; Fe65 N-terminal Phosphotyrosine-binding (PTB) domain
    cl17171
    Location:284342
    PH-like; Pleckstrin homology-like domain

Alternate Mm_Celera

Genomic

  1. AC_000040.1 Alternate Mm_Celera

    Range
    37120261..37128499 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)