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Trpv2 transient receptor potential cation channel, subfamily V, member 2 [ Mus musculus (house mouse) ]

Gene ID: 22368, updated on 8-May-2016
Official Symbol
Trpv2provided by MGI
Official Full Name
transient receptor potential cation channel, subfamily V, member 2provided by MGI
Primary source
MGI:MGI:1341836
See related
Ensembl:ENSMUSG00000018507 Vega:OTTMUSG00000005868
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
GRC; Vrl1; VRL-1; OTRPC2
Orthologs
Location:
11; 11 B2
Exon count:
18
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 11 NC_000077.6 (62574486..62600305)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (62387988..62413807)

Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene predicted gene 12279 Neighboring gene ubiquitin B Neighboring gene RIKEN cDNA 2410006H16 gene Neighboring gene small nucleolar RNA, C/D box 49B Neighboring gene small nucleolar RNA, C/D box 49A

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
calcium channel activity IDA
Inferred from Direct Assay
more info
PubMed 
cation channel activity IDA
Inferred from Direct Assay
more info
PubMed 
cation channel activity ISO
Inferred from Sequence Orthology
more info
PubMed 
ion channel activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
NOT apoptotic process IDA
Inferred from Direct Assay
more info
PubMed 
calcium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
calcium ion transport IEA
Inferred from Electronic Annotation
more info
 
ion transport IEA
Inferred from Electronic Annotation
more info
 
negative regulation of cell proliferation ISO
Inferred from Sequence Orthology
more info
 
positive regulation of axon extension IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of calcium ion import IMP
Inferred from Mutant Phenotype
more info
PubMed 
response to heat ISO
Inferred from Sequence Orthology
more info
 
response to temperature stimulus ISO
Inferred from Sequence Orthology
more info
PubMed 
transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
axon IDA
Inferred from Direct Assay
more info
PubMed 
axonal growth cone IDA
Inferred from Direct Assay
more info
PubMed 
cell body IDA
Inferred from Direct Assay
more info
PubMed 
cell surface IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
endomembrane system ISO
Inferred from Sequence Orthology
more info
 
growth cone membrane IDA
Inferred from Direct Assay
more info
PubMed 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
intracellular IDA
Inferred from Direct Assay
more info
PubMed 
lamellipodium ISO
Inferred from Sequence Orthology
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane ISO
Inferred from Sequence Orthology
more info
PubMed 
Preferred Names
transient receptor potential cation channel subfamily V member 2
Names
growth factor regulated channel
growth factor-regulated calcium channel
osm-9-like TRP channel 2
vanilloid receptor-like protein 1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_011706.2NP_035836.2  transient receptor potential cation channel subfamily V member 2

    See identical proteins and their annotated locations for NP_035836.2

    Status: VALIDATED

    Source sequence(s)
    AK008689, BB631765, BY648241
    Consensus CDS
    CCDS24827.1
    UniProtKB/Swiss-Prot
    Q9WTR1
    Related
    ENSMUSP00000018651, OTTMUSP00000006068, ENSMUST00000018651, OTTMUST00000013064
    Conserved Domains (2) summary
    cd00204
    Location:159310
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    TIGR00870
    Location:27756
    trp; transient-receptor-potential calcium channel protein

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000077.6 Reference GRCm38.p3 C57BL/6J

    Range
    62574486..62600305
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011248971.1XP_011247273.1  

    See identical proteins and their annotated locations for XP_011247273.1

    UniProtKB/Swiss-Prot
    Q9WTR1
    Conserved Domains (2) summary
    cd00204
    Location:159310
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    TIGR00870
    Location:27756
    trp; transient-receptor-potential calcium channel protein
  2. XM_011248970.1XP_011247272.1  

    See identical proteins and their annotated locations for XP_011247272.1

    UniProtKB/Swiss-Prot
    Q9WTR1
    Conserved Domains (2) summary
    cd00204
    Location:159310
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    TIGR00870
    Location:27756
    trp; transient-receptor-potential calcium channel protein
  3. XM_006533165.1XP_006533228.1  

    See identical proteins and their annotated locations for XP_006533228.1

    UniProtKB/Swiss-Prot
    Q9WTR1
    Related
    ENSMUSP00000099703, OTTMUSP00000006069, ENSMUST00000102643, OTTMUST00000013066
    Conserved Domains (2) summary
    cd00204
    Location:159310
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    TIGR00870
    Location:27756
    trp; transient-receptor-potential calcium channel protein

Alternate Mm_Celera

Genomic

  1. AC_000033.1 Alternate Mm_Celera

    Range
    69494115..69519933
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)