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    CCDC7 coiled-coil domain containing 7 [ Homo sapiens ]

    Gene ID: 221016, updated on 11-May-2012
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    Summary

    Official Symbol
    CCDC7provided by HGNC
    Official Full Name
    coiled-coil domain containing 7provided by HGNC
    Primary source
    HGNC:26533
    Locus tag
    RP11-195O1.4
    See related
    Ensembl:ENSG00000216937; HPRD:10812; Vega:OTTHUMG00000150517
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    BioT2-A; BioT2-B; BioT2-C; FLJ32762; RP11-479G22.1; DKFZp686N0559
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    Genomic context

    Location :
    10p11.22
    Sequence :
    Chromosome: 10; NC_000010.10 (32735041..32863492)
    See CCDC7 in Epigenomics, MapViewer

    Chromosome 10 - NC_000010.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC100652971 Neighboring gene enhancer of polycomb homolog 1 (Drosophila) Neighboring gene C1D nuclear receptor corepressor pseudogene 1 Neighboring gene chromosome 10 open reading frame 68 Neighboring gene integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) Neighboring gene uncharacterized LOC100505562 Neighboring gene adenylate kinase 3 pseudogene 5 Neighboring gene ribosomal protein L7a pseudogene 53

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    Genomic regions, transcripts, and products

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details
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    Bibliography

    Related articles in PubMed

    1. A cohesin-RAD21 interactome. Panigrahi AK, et al. Biochem J, 2012 Mar 15. PMID 22145905.
    2. Novel gene hBiot2 is an independent prognostic factor in colorectal cancer patients. Shen YM, et al. Oncol Rep, 2012 Feb. PMID 22024937.
    3. Overexpression of the hBiot2 gene is associated with development of human cervical cancer. Shen YM, et al. Oncol Rep, 2011 Jan. PMID 21109960.
    4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.
    5. RNA interference against Biot2, a novel mouse testis-specific gene, inhibits the growth of tumor cells. Wang CT, et al. Cell Mol Biol Lett, 2009. PMID 19277478.

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    1. A higher expression of hBiot2 in primary CRC patients independently indicates a poorer prognosis.
      Title: Novel gene hBiot2 is an independent prognostic factor in colorectal cancer patients.
    2. Overexpression of hBiot2 is associated with early and interim development of human cervical cancer.
      Title: Overexpression of the hBiot2 gene is associated with development of human cervical cancer.
    3. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
      Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
    4. Observational study of gene-disease association. (HuGE Navigator)
      Title: A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.
    Submit: New GeneRIF Correction
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    Phenotypes

    Review eQTL and phenotype association data in this region using PheGenI

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    Interactions

    Products Interactant Other Gene Complex Source Pubs Description
    Q96M83 O76071 CIAO1    HPRD  PubMed  
    Q96M83 Q01844 EWSR1    HPRD  PubMed  
    BioGRID:128674 BioGRID:114791 CIAO1    BioGRID  PubMed Two-hybrid 
    BioGRID:128674 BioGRID:108431 EWSR1    BioGRID  PubMed Two-hybrid 
    BioGRID:128674 BioGRID:111822 RAD21    BioGRID  PubMed Affinity Capture-Western 
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    General gene information

    Markers

    Genotypes

    Homology

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    General protein information

    Preferred Names
    coiled-coil domain-containing protein 7
    Names
    coiled-coil domain-containing protein 7
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    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001026383.1 → NP_001021554.1  coiled-coil domain-containing protein 7

      Status: VALIDATED

      Source sequence(s)
      BC022020, BC042672, BI462512
      Consensus CDS
      CCDS7173.1
      UniProtKB/Swiss-Prot
      Q96M83
      Related
      ENSP00000277657, OTTHUMP00000019417, ENST00000277657, OTTHUMT00000047489

    2. NM_145023.4 → NP_659460.3  coiled-coil domain-containing protein 7

      Status: VALIDATED

      Source sequence(s)
      BC022020, BC042672, BI462512
      Consensus CDS
      CCDS7173.1
      UniProtKB/Swiss-Prot
      Q96M83
      Related
      ENSP00000355078, OTTHUMP00000019418, ENST00000362006, OTTHUMT00000047490

    RefSeqs of Annotated Genomes: Build 37.3

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh37.p5 Primary Assembly

    Genomic

    1. NC_000010.10 Reference GRCh37.p5 Primary Assembly

      Range
      32735041..32863492
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate HuRef

    Genomic

    1. AC_000142.1 Alternate HuRef

      Range
      32454753..32583158
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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    Related Sequences

    Nucleotide Protein
    Heading Accession and Version
    genomic AL354750.12 CAI39704.1
      CAI39706.1
    genomic AL354750.12 CAI39704.1
      CAI39706.1
    genomic AL391839.9 CAH70456.1
    genomic CH471072.2 EAW85964.1
      EAW85965.1
      EAW85966.1
    mRNA AK057324.1 BAB71426.1
    mRNA AK058148.1 BAB71686.1
    mRNA BC022020.2 AAH22020.2
    mRNA BC042672.1 AAH42672.1
    mRNA BI462512.1 None
    mRNA BX647771.1 CAI46051.1
    mRNA EF656618.1 ABR88143.1
    mRNA EF656619.1 ABR88144.1
    mRNA EF656620.1 ABR88145.1
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5HYG3 GenPept UniProtKB/TrEMBL:Q5HYG3
    Q5JTR9 GenPept UniProtKB/TrEMBL:Q5JTR9
    Q96LK5 GenPept UniProtKB/TrEMBL:Q96LK5
    Q96M83.2 GenPept UniProtKB/Swiss-Prot:Q96M83
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    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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