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Trpc1 transient receptor potential cation channel, subfamily C, member 1 [ Mus musculus (house mouse) ]

Gene ID: 22063, updated on 8-May-2016
Official Symbol
Trpc1provided by MGI
Official Full Name
transient receptor potential cation channel, subfamily C, member 1provided by MGI
Primary source
MGI:MGI:109528
See related
Ensembl:ENSMUSG00000032839 Vega:OTTMUSG00000047293
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Trp1; Mtrp1; Trrp1
Orthologs
Location:
9 50.2 cM; 9 E4
Exon count:
15
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 9 NC_000075.6 (95705072..95750390, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (95607046..95650777, complement)

Chromosome 9 - NC_000075.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 39406 Neighboring gene predicted gene, 32542 Neighboring gene procollagen C-endopeptidase enhancer 2 Neighboring gene inosine triphosphatase (nucleoside triphosphate pyrophosphatase) pseudogene 2 Neighboring gene predicted gene, 39407 Neighboring gene plastin 1 (I-isoform) Neighboring gene RIKEN cDNA 1700065D16 gene Neighboring gene ataxia telangiectasia and Rad3 related

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
calcium channel activity IEA
Inferred from Electronic Annotation
more info
 
cation channel activity ISO
Inferred from Sequence Orthology
more info
 
inositol 1,4,5 trisphosphate binding ISO
Inferred from Sequence Orthology
more info
 
ion channel activity IEA
Inferred from Electronic Annotation
more info
 
ion channel binding ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
store-operated calcium channel activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
Process Evidence Code Pubs
calcium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
calcium ion transport IEA
Inferred from Electronic Annotation
more info
 
ion transport IEA
Inferred from Electronic Annotation
more info
 
manganese ion transport IBA
Inferred from Biological aspect of Ancestor
more info
 
melanin biosynthetic process ISO
Inferred from Sequence Orthology
more info
 
positive regulation of release of sequestered calcium ion into cytosol ISO
Inferred from Sequence Orthology
more info
 
regulation of cytosolic calcium ion concentration IBA
Inferred from Biological aspect of Ancestor
more info
 
regulation of cytosolic calcium ion concentration ISO
Inferred from Sequence Orthology
more info
 
response to calcium ion ISO
Inferred from Sequence Orthology
more info
 
saliva secretion IMP
Inferred from Mutant Phenotype
more info
PubMed 
transmembrane transport IEA
Inferred from Electronic Annotation
more info
 
transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
basolateral plasma membrane IMP
Inferred from Mutant Phenotype
more info
PubMed 
costamere IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
membrane raft IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 
protein complex IPI
Inferred from Physical Interaction
more info
PubMed 
receptor complex ISO
Inferred from Sequence Orthology
more info
PubMed 
sarcomere IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
short transient receptor potential channel 1
Names
TRP-1
transient receptor protein 1
trp-related protein 1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001311123.1NP_001298052.1  short transient receptor potential channel 1 isoform 2

    See identical proteins and their annotated locations for NP_001298052.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region compared to variant 1. It encodes isoform 2, which is shorter than isoform 1.
    Source sequence(s)
    AC091531, AK005144, BC144726, BP762453
    Consensus CDS
    CCDS81052.1
    UniProtKB/Swiss-Prot
    Q61056
    UniProtKB/TrEMBL
    B7ZMP6
    Conserved Domains (3) summary
    cd00204
    Location:67162
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam08344
    Location:175237
    TRP_2; Transient receptor ion channel II
    TIGR00870
    Location:64756
    trp; transient-receptor-potential calcium channel protein
  2. NM_011643.3NP_035773.1  short transient receptor potential channel 1 isoform 1

    See identical proteins and their annotated locations for NP_035773.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AC091531, AK005144, BC137581, BP762453
    Consensus CDS
    CCDS23411.1
    UniProtKB/Swiss-Prot
    Q61056
    UniProtKB/TrEMBL
    B2RPS7
    Related
    ENSMUSP00000139672, OTTMUSP00000067131, ENSMUST00000189137, OTTMUST00000122275
    Conserved Domains (3) summary
    cd00204
    Location:67195
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam08344
    Location:209271
    TRP_2; Transient receptor ion channel II
    TIGR00870
    Location:64790
    trp; transient-receptor-potential calcium channel protein

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000075.6 Reference GRCm38.p3 C57BL/6J

    Range
    95705072..95750390 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006511054.2XP_006511117.1  

    Related
    ENSMUSP00000057640, OTTMUSP00000067132, ENSMUST00000053785, OTTMUST00000122276
    Conserved Domains (3) summary
    cd00204
    Location:67162
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam08344
    Location:175237
    TRP_2; Transient receptor ion channel II
    TIGR00870
    Location:64756
    trp; transient-receptor-potential calcium channel protein
  2. XM_006511053.2XP_006511116.1  

    Conserved Domains (3) summary
    cd00204
    Location:67195
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam08344
    Location:209264
    TRP_2; Transient receptor ion channel II
    TIGR00870
    Location:64783
    trp; transient-receptor-potential calcium channel protein
  3. XM_006511056.2XP_006511119.1  

    See identical proteins and their annotated locations for XP_006511119.1

    Conserved Domains (2) summary
    pfam00520
    Location:325513
    Ion_trans; Ion transport protein
    pfam08344
    Location:61123
    TRP_2; Transient receptor ion channel II
  4. XM_006511055.2XP_006511118.1  

    See identical proteins and their annotated locations for XP_006511118.1

    Conserved Domains (2) summary
    pfam00520
    Location:359547
    Ion_trans; Ion transport protein
    pfam08344
    Location:95157
    TRP_2; Transient receptor ion channel II
  5. XM_006511057.1XP_006511120.1  

    Conserved Domains (2) summary
    pfam00520
    Location:312500
    Ion_trans; Ion transport protein
    pfam08344
    Location:48110
    TRP_2; Transient receptor ion channel II
  6. XM_011242717.1XP_011241019.1  

    Conserved Domains (3) summary
    cd00204
    Location:67195
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    pfam08344
    Location:209271
    TRP_2; Transient receptor ion channel II
    pfam12796
    Location:67150
    Ank_2; Ankyrin repeats (3 copies)

RNA

  1. XR_870756.1 RNA Sequence

Alternate Mm_Celera

Genomic

  1. AC_000031.1 Alternate Mm_Celera

    Range
    95273759..95317486 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)