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Dedd death effector domain-containing [ Mus musculus (house mouse) ]

Gene ID: 21945, updated on 19-Sep-2014
Official Symbol
Deddprovided by MGI
Official Full Name
death effector domain-containingprovided by MGI
Primary source
MGI:MGI:1333874
See related
Ensembl:ENSMUSG00000013973; Vega:OTTMUSG00000021703
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
DEFT; KE05; FLDED1; Dedpro1; CASP8IP1
See Dedd in Epigenomics, MapViewer
Location:
1 H2; 1 79.34 cM
Exon count:
8
Annotation release Status Assembly Chr Location
104 current GRCm38.p2 (GCF_000001635.22) 1 NC_000067.6 (171329145..171342501)

Chromosome 1 - NC_000067.6Genomic Context describing neighboring genes Neighboring gene ubiquitin-fold modifier conjugating enzyme 1 Neighboring gene ribosomal protein L27, pseudogene 1 Neighboring gene nitrilase 1 Neighboring gene prefoldin 2 Neighboring gene kelch domain containing 9

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
DNA binding IDA
Inferred from Direct Assay
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
apoptotic process IEA
Inferred from Electronic Annotation
more info
 
decidualization IMP
Inferred from Mutant Phenotype
more info
 
extrinsic apoptotic signaling pathway via death domain receptors IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of protein catabolic process IMP
Inferred from Mutant Phenotype
more info
 
negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter IDA
Inferred from Direct Assay
more info
PubMed 
regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
nucleolus IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
death effector domain-containing protein
Names
death effector domain-containing protein
tumor necrosis factor (ligand) superfamily, member 19

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001128609.1NP_001122081.1  death effector domain-containing protein

    See proteins identical to NP_001122081.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) is the longer transcript. Both variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC084821, AK009728, BM947911
    Consensus CDS
    CCDS15490.1
    UniProtKB/TrEMBL
    Q3U001
    UniProtKB/Swiss-Prot
    Q9Z1L3
    Related
    ENSMUSP00000106931, OTTMUSP00000024250, ENSMUST00000111300, OTTMUST00000051499
    Conserved Domains (1) summary
    cd08790
    Location:22118
    DED_DEDD; Death Effector Domain of DEDD
  2. NM_011615.3NP_035745.3  death effector domain-containing protein

    See proteins identical to NP_035745.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an internal 5' UTR exon, as compared to variant 1.
    Source sequence(s)
    AC084821, AK009728, BM947911
    Consensus CDS
    CCDS15490.1
    UniProtKB/TrEMBL
    Q3U001
    UniProtKB/Swiss-Prot
    Q9Z1L3
    Conserved Domains (1) summary
    cd08790
    Location:22118
    DED_DEDD; Death Effector Domain of DEDD

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 104

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p2 C57BL/6J

Genomic

  1. NC_000067.6 

    Range
    171329145..171342501
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006496739.1XP_006496802.1  

    See proteins identical to XP_006496802.1

    UniProtKB/TrEMBL
    Q3U001
    UniProtKB/Swiss-Prot
    Q9Z1L3
    Related
    ENSMUSP00000068419, OTTMUSP00000024257, ENSMUST00000064950, OTTMUST00000051512
    Conserved Domains (1) summary
    cd08790
    Location:22118
    DED_DEDD; Death Effector Domain of DEDD
  2. XM_006496738.1XP_006496801.1  

    See proteins identical to XP_006496801.1

    UniProtKB/TrEMBL
    Q3U001
    UniProtKB/Swiss-Prot
    Q9Z1L3
    Conserved Domains (1) summary
    cd08790
    Location:22118
    DED_DEDD; Death Effector Domain of DEDD
  3. XM_006496740.1XP_006496803.1  

    See proteins identical to XP_006496803.1

    UniProtKB/TrEMBL
    Q3U001
    UniProtKB/Swiss-Prot
    Q9Z1L3
    Conserved Domains (1) summary
    cd08790
    Location:22118
    DED_DEDD; Death Effector Domain of DEDD
  4. XM_006496741.1XP_006496804.1  

    See proteins identical to XP_006496804.1

    UniProtKB/TrEMBL
    Q3U001
    UniProtKB/Swiss-Prot
    Q9Z1L3
    Related
    ENSMUSP00000095075, OTTMUSP00000024259, ENSMUST00000097467, OTTMUST00000051514
    Conserved Domains (1) summary
    cd08790
    Location:22118
    DED_DEDD; Death Effector Domain of DEDD

Alternate Mm_Celera

Genomic

  1. AC_000023.1 

    Range
    173780626..173793989
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)