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Tnfrsf1b tumor necrosis factor receptor superfamily, member 1b [ Mus musculus (house mouse) ]

Gene ID: 21938, updated on 22-May-2016
Official Symbol
Tnfrsf1bprovided by MGI
Official Full Name
tumor necrosis factor receptor superfamily, member 1bprovided by MGI
Primary source
MGI:MGI:1314883
See related
Ensembl:ENSMUSG00000028599
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
p75; TNFBR; Tnfr2; CD120b; TNF-R2; TNFR80; TNFRII; Tnfr-1; TNF-R75; TNF-R-II; TNF-alphaR2; TNFalpha-R2
Orthologs
Location:
4 E1; 4 78.17 cM
Exon count:
10
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 4 NC_000070.6 (145212368..145246870, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (144802271..144836773, complement)

Chromosome 4 - NC_000070.6Genomic Context describing neighboring genes Neighboring gene vacuolar protein sorting 13D Neighboring gene predicted gene, 36317 Neighboring gene predicted gene, 42343 Neighboring gene predicted gene, 36233 Neighboring gene tumor necrosis factor receptor superfamily, member 8

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
tumor necrosis factor-activated receptor activity IPI
Inferred from Physical Interaction
more info
PubMed 
tumor necrosis factor-activated receptor activity ISO
Inferred from Sequence Orthology
more info
 
ubiquitin protein ligase binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
RNA destabilization IMP
Inferred from Mutant Phenotype
more info
PubMed 
cell proliferation TAS
Traceable Author Statement
more info
PubMed 
cell surface receptor signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
cellular response to lipopolysaccharide ISO
Inferred from Sequence Orthology
more info
 
extrinsic apoptotic signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
immune response IBA
Inferred from Biological aspect of Ancestor
more info
 
immune response ISO
Inferred from Sequence Orthology
more info
 
inflammatory response IMP
Inferred from Mutant Phenotype
more info
PubMed 
intrinsic apoptotic signaling pathway in response to DNA damage IMP
Inferred from Mutant Phenotype
more info
PubMed 
multicellular organism development IBA
Inferred from Biological aspect of Ancestor
more info
 
negative regulation of inflammatory response IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of MAPK cascade IBA
Inferred from Biological aspect of Ancestor
more info
 
positive regulation of membrane protein ectodomain proteolysis ISO
Inferred from Sequence Orthology
more info
 
regulation of apoptotic process IBA
Inferred from Biological aspect of Ancestor
more info
 
regulation of cell proliferation IBA
Inferred from Biological aspect of Ancestor
more info
 
response to lipopolysaccharide IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
axon ISO
Inferred from Sequence Orthology
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
membrane IDA
Inferred from Direct Assay
more info
PubMed 
membrane ISO
Inferred from Sequence Orthology
more info
 
membrane raft IDA
Inferred from Direct Assay
more info
PubMed 
membrane raft ISO
Inferred from Sequence Orthology
more info
 
neuronal cell body ISO
Inferred from Sequence Orthology
more info
 
nucleus ISO
Inferred from Sequence Orthology
more info
 
perinuclear region of cytoplasm ISO
Inferred from Sequence Orthology
more info
 
varicosity ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
tumor necrosis factor receptor superfamily member 1B
Names
TNF receptor beta chain
TNF-RII
TNFR-II
p75 TNFR
p80 TNF-alpha receptor
tumor necrosis factor receptor 2
tumor necrosis factor receptor type II

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_011610.3NP_035740.2  tumor necrosis factor receptor superfamily member 1B precursor

    See identical proteins and their annotated locations for NP_035740.2

    Status: VALIDATED

    Source sequence(s)
    AK140332, BY489212
    Consensus CDS
    CCDS18914.1
    UniProtKB/Swiss-Prot
    P25119
    UniProtKB/TrEMBL
    Q545P4
    Related
    ENSMUSP00000030336, OTTMUSP00000010647, ENSMUST00000030336, OTTMUST00000023284
    Conserved Domains (1) summary
    cd10577
    Location:40203
    TNFRSF1B; Tumor necrosis factor receptor superfamily member 1B (TNFRSF1B), also known as TNFR2

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000070.6 Reference GRCm38.p3 C57BL/6J

    Range
    145212368..145246870 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000026.1 Alternate Mm_Celera

    Range
    146801795..146837140 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)