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Tgm3 transglutaminase 3, E polypeptide [ Mus musculus (house mouse) ]

Gene ID: 21818, updated on 28-May-2016
Official Symbol
Tgm3provided by MGI
Official Full Name
transglutaminase 3, E polypeptideprovided by MGI
Primary source
MGI:MGI:98732
See related
Ensembl:ENSMUSG00000027401 Vega:OTTMUSG00000015499
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
we; TGE; TG E; TG(E); TGase E; TGase-3; AI893889
Orthologs
Location:
2; 2 F1
Exon count:
15
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 2 NC_000068.7 (129987794..130050399)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (129838110..129876135)

Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4932416H05 gene Neighboring gene serine/threonine kinase 35 Neighboring gene predicted gene, 39933 Neighboring gene microRNA 6339 Neighboring gene expressed sequence AU015228 Neighboring gene transglutaminase 6

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Associated conditions

Description Tests
wellhaarig
GeneReviews: Not available

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Markers

Homology

Clone Names

  • MGC150256, MGC150257

Gene Ontology Provided by MGI

Function Evidence Code Pubs
calcium ion binding ISO
Inferred from Sequence Orthology
more info
 
catalytic activity ISO
Inferred from Sequence Orthology
more info
 
catalytic activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
protein-glutamine gamma-glutamyltransferase activity ISO
Inferred from Sequence Orthology
more info
 
protein-glutamine gamma-glutamyltransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
transferase activity, transferring acyl groups IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
cell envelope organization ISO
Inferred from Sequence Orthology
more info
 
epidermis development TAS
Traceable Author Statement
more info
PubMed 
hair cell differentiation TAS
Traceable Author Statement
more info
PubMed 
keratinization IEA
Inferred from Electronic Annotation
more info
 
peptide cross-linking ISO
Inferred from Sequence Orthology
more info
 
peptide cross-linking TAS
Traceable Author Statement
more info
PubMed 
protein tetramerization ISO
Inferred from Sequence Orthology
more info
 
skin development TAS
Traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
cornified envelope TAS
Traceable Author Statement
more info
PubMed 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
extracellular exosome ISO
Inferred from Sequence Orthology
more info
 
extrinsic component of cytoplasmic side of plasma membrane ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
protein-glutamine gamma-glutamyltransferase E
Names
E polypeptide
protein-glutamine-gamma-glutamyltransferase
transglutaminase E
transglutaminase-3
NP_033400.2

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_009374.3NP_033400.2  protein-glutamine gamma-glutamyltransferase E precursor

    See identical proteins and their annotated locations for NP_033400.2

    Status: VALIDATED

    Source sequence(s)
    AL808127
    Consensus CDS
    CCDS38240.1
    UniProtKB/Swiss-Prot
    Q08189
    Related
    ENSMUSP00000105928, OTTMUSP00000016514, ENSMUST00000110299, OTTMUST00000036811
    Conserved Domains (3) summary
    smart00460
    Location:265357
    TGc; Transglutaminase/protease-like homologues
    pfam00868
    Location:4120
    Transglut_N; Transglutaminase family
    pfam00927
    Location:595693
    Transglut_C; Transglutaminase family, C-terminal ig like domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000068.7 Reference GRCm38.p3 C57BL/6J

    Range
    129987794..130050399
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011239437.1XP_011237739.1  

    Conserved Domains (3) summary
    smart00460
    Location:271363
    TGc; Transglutaminase/protease-like homologues
    pfam00868
    Location:10126
    Transglut_N; Transglutaminase family
    pfam00927
    Location:601699
    Transglut_C; Transglutaminase family, C-terminal ig like domain
  2. XM_006499151.2XP_006499214.1  

    Conserved Domains (3) summary
    smart00460
    Location:276368
    TGc; Transglutaminase/protease-like homologues
    pfam00868
    Location:15131
    Transglut_N; Transglutaminase family
    pfam00927
    Location:606704
    Transglut_C; Transglutaminase family, C-terminal ig like domain

Alternate Mm_Celera

Genomic

  1. AC_000024.1 Alternate Mm_Celera

    Range
    131240745..131278693
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)