Format

Send to:

Choose Destination

Eif5 eukaryotic translation initiation factor 5 [ Mus musculus (house mouse) ]

Gene ID: 217869, updated on 8-May-2016
Official Symbol
Eif5provided by MGI
Official Full Name
eukaryotic translation initiation factor 5provided by MGI
Primary source
MGI:MGI:95309
See related
Ensembl:ENSMUSG00000021282
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
D12Ertd549e; 2810011H21Rik
Orthologs
Location:
12 F1; 12 61.03 cM
Exon count:
12
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 12 NC_000078.6 (111538101..111546753)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 12 NC_000078.5 (112776312..112784964)

Chromosome 12 - NC_000078.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 36292 Neighboring gene predicted gene, 38705 Neighboring gene predicted gene, 40578 Neighboring gene small nucleolar RNA, H/ACA box 28 Neighboring gene RIKEN cDNA 2810029C07 gene Neighboring gene MAP/microtubule affinity regulating kinase 3

Markers

Homology

Clone Names

  • MGC36374, MGC36509

Gene Ontology Provided by MGI

Function Evidence Code Pubs
GTP binding IEA
Inferred from Electronic Annotation
more info
 
eukaryotic initiation factor eIF2 binding ISO
Inferred from Sequence Orthology
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
poly(A) RNA binding ISO
Inferred from Sequence Orthology
more info
 
translation initiation factor activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
activation of GTPase activity ISO
Inferred from Sequence Orthology
more info
 
formation of translation preinitiation complex ISO
Inferred from Sequence Orthology
more info
 
regulation of translational initiation ISO
Inferred from Sequence Orthology
more info
 
translation IEA
Inferred from Electronic Annotation
more info
 
translational initiation IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
eukaryotic translation initiation factor 5
Names
eIF-5

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_173363.5NP_775539.1  eukaryotic translation initiation factor 5

    See identical proteins and their annotated locations for NP_775539.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represent the longer transcript. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AI391022, AK160828, AK163368, AW547465
    Consensus CDS
    CCDS26180.1
    UniProtKB/Swiss-Prot
    P59325
    UniProtKB/TrEMBL
    Q3TQR3
    Related
    ENSMUSP00000126825, ENSMUST00000166123
    Conserved Domains (2) summary
    cd11561
    Location:231383
    W2_eIF5; C-terminal W2 domain of eukaryotic translation initiation factor 5
    pfam01873
    Location:2130
    eIF-5_eIF-2B; Domain found in IF2B/IF5
  2. NM_178041.2NP_829887.1  eukaryotic translation initiation factor 5

    See identical proteins and their annotated locations for NP_829887.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses a different splice site in its 5' UTR, compared to variant 1. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AI391022, AK159232, AK160828, AW547465
    Consensus CDS
    CCDS26180.1
    UniProtKB/Swiss-Prot
    P59325
    UniProtKB/TrEMBL
    Q3TQR3
    Conserved Domains (2) summary
    cd11561
    Location:231383
    W2_eIF5; C-terminal W2 domain of eukaryotic translation initiation factor 5
    pfam01873
    Location:2130
    eIF-5_eIF-2B; Domain found in IF2B/IF5

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000078.6 Reference GRCm38.p3 C57BL/6J

    Range
    111538101..111546753
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000034.1 Alternate Mm_Celera

    Range
    112732164..112740796
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)