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Abca5 ATP-binding cassette, sub-family A (ABC1), member 5 [ Mus musculus (house mouse) ]

Gene ID: 217265, updated on 8-May-2016
Official Symbol
Abca5provided by MGI
Official Full Name
ATP-binding cassette, sub-family A (ABC1), member 5provided by MGI
Primary source
MGI:MGI:2386607
See related
Ensembl:ENSMUSG00000018800 Vega:OTTMUSG00000003326
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
ABC13; mKIAA1888; B930033A02Rik
Orthologs
Location:
11; 11 E1
Exon count:
39
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 11 NC_000077.6 (110269369..110337724, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (110130683..110199030, complement)

Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene ATP-binding cassette, sub-family A (ABC1), member 9 Neighboring gene ATP-binding cassette, sub-family A (ABC1), member 6 Neighboring gene predicted gene, 39445 Neighboring gene mitogen-activated protein kinase kinase 6 Neighboring gene predicted gene, 39446

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • ABC transporters, organism-specific biosystem (from KEGG)
    ABC transporters, organism-specific biosystemThe ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of ...
  • ABC transporters, conserved biosystem (from KEGG)
    ABC transporters, conserved biosystemThe ATP-binding cassette (ABC) transporters form one of the largest known protein families, and are widespread in bacteria, archaea, and eukaryotes. They couple ATP hydrolysis to active transport of ...

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
ATPase activity IEA
Inferred from Electronic Annotation
more info
 
ATPase activity, coupled to transmembrane movement of substances IBA
Inferred from Biological aspect of Ancestor
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
transporter activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
cholesterol efflux IMP
Inferred from Mutant Phenotype
more info
PubMed 
high-density lipoprotein particle remodeling IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of macrophage derived foam cell differentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
reverse cholesterol transport IC
Inferred by Curator
more info
PubMed 
transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
endosome IEA
Inferred from Electronic Annotation
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
late endosome IDA
Inferred from Direct Assay
more info
PubMed 
lysosome IDA
Inferred from Direct Assay
more info
PubMed 
membrane IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
ATP-binding cassette sub-family A member 5
Names
ATP-binding cassette transporter sub-family A member 5

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_147219.2NP_671752.2  ATP-binding cassette sub-family A member 5

    See identical proteins and their annotated locations for NP_671752.2

    Status: VALIDATED

    Source sequence(s)
    AK035955, AK046203, AK047188, AK129463, AK138604, BC053340, CJ115212
    Consensus CDS
    CCDS25591.1
    UniProtKB/Swiss-Prot
    Q8K448
    Related
    ENSMUSP00000047927, OTTMUSP00000003319, ENSMUST00000043961, OTTMUST00000006988
    Conserved Domains (3) summary
    cd03263
    Location:478701
    ABC_subfamily_A; ATP-binding cassette domain of the lipid transporters, subfamily A
    COG1131
    Location:12881615
    CcmA; ABC-type multidrug transport system, ATPase component [Defense mechanisms]
    pfam12698
    Location:212416
    ABC2_membrane_3; ABC-2 family transporter protein

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000077.6 Reference GRCm38.p3 C57BL/6J

    Range
    110269369..110337724 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006533065.2XP_006533128.1  

    See identical proteins and their annotated locations for XP_006533128.1

    UniProtKB/Swiss-Prot
    Q8K448
    Conserved Domains (3) summary
    cd03263
    Location:478701
    ABC_subfamily_A; ATP-binding cassette domain of the lipid transporters, subfamily A
    COG1131
    Location:12881615
    CcmA; ABC-type multidrug transport system, ATPase component [Defense mechanisms]
    pfam12698
    Location:212416
    ABC2_membrane_3; ABC-2 family transporter protein
  2. XM_011248946.1XP_011247248.1  

    Conserved Domains (3) summary
    cd03263
    Location:478701
    ABC_subfamily_A; ATP-binding cassette domain of the lipid transporters, subfamily A
    COG1131
    Location:476788
    CcmA; ABC-type multidrug transport system, ATPase component [Defense mechanisms]
    pfam12698
    Location:212416
    ABC2_membrane_3; ABC-2 family transporter protein

Alternate Mm_Celera

Genomic

  1. AC_000033.1 Alternate Mm_Celera

    Range
    122007376..122077299 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)