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Nags N-acetylglutamate synthase [ Mus musculus (house mouse) ]

Gene ID: 217214, updated on 28-May-2016
Official Symbol
Nagsprovided by MGI
Official Full Name
N-acetylglutamate synthaseprovided by MGI
Primary source
MGI:MGI:2387600
See related
Ensembl:ENSMUSG00000048217 Vega:OTTMUSG00000002350
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
argA; 1700120E20Rik
Orthologs
Location:
11; 11 D
Exon count:
7
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 11 NC_000077.6 (102145513..102149528)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (102006901..102010790)

Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene ribosomal protein S2 pseudogene Neighboring gene predicted gene, 39394 Neighboring gene Ppih pseudogene Neighboring gene predicted gene 11586 Neighboring gene transmembrane protein 101 Neighboring gene LSM12 homolog

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (1) 

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
acetyl-CoA:L-glutamate N-acetyltransferase activity IDA
Inferred from Direct Assay
more info
PubMed 
acetyl-CoA:L-glutamate N-acetyltransferase activity ISO
Inferred from Sequence Orthology
more info
 
arginine binding IBA
Inferred from Biological aspect of Ancestor
more info
 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
transferase activity, transferring acyl groups IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
arginine biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
 
glutamate metabolic process IDA
Inferred from Direct Assay
more info
PubMed 
urea cycle IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
mitochondrion IDA
Inferred from Direct Assay
more info
PubMed 
mitochondrion TAS
Traceable Author Statement
more info
PubMed 
Preferred Names
N-acetylglutamate synthase, mitochondrial
Names
amino-acid N-acetyltransferase
amino-acid acetyltransferase
NP_665828.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_145829.2NP_665828.1  N-acetylglutamate synthase, mitochondrial precursor

    See identical proteins and their annotated locations for NP_665828.1

    Status: VALIDATED

    Source sequence(s)
    AI415708, AK075765, AL591145
    Consensus CDS
    CCDS25488.1
    UniProtKB/Swiss-Prot
    Q8R4H7
    Related
    ENSMUSP00000050258, OTTMUSP00000002248, ENSMUST00000055409, OTTMUST00000004679
    Conserved Domains (3) summary
    cd04265
    Location:398497
    DUF619-NAGS-U; DUF619 domain of various N-acetylglutamate Synthases (NAGS) of the urea (U) cycle of humans and fish
    PRK04531
    Location:108518
    PRK04531; acetylglutamate kinase; Provisional
    cl00452
    Location:95364
    AAK; Amino Acid Kinases (AAK) superfamily, catalytic domain; present in such enzymes like N-acetylglutamate kinase (NAGK), carbamate kinase (CK), aspartokinase (AK), glutamate-5-kinase (G5K) and UMP kinase (UMPK). The AAK superfamily includes kinases that ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000077.6 Reference GRCm38.p3 C57BL/6J

    Range
    102145513..102149528
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000033.1 Alternate Mm_Celera

    Range
    113851261..113855276
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_178053.4: Suppressed sequence

    Description
    NM_178053.4: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.