Format

Send to:

Choose Destination

Tada2a transcriptional adaptor 2A [ Mus musculus (house mouse) ]

Gene ID: 217031, updated on 28-May-2016
Official Symbol
Tada2aprovided by MGI
Official Full Name
transcriptional adaptor 2Aprovided by MGI
Primary source
MGI:MGI:2144471
See related
Ensembl:ENSMUSG00000018651 Vega:OTTMUSG00000000969
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Tada2l; AV319371; D030022J10Rik
Orthologs
Location:
11; 11 C
Exon count:
17
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 11 NC_000077.6 (84078920..84129642, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (83892422..83943070, complement)

Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene synergin, gamma Neighboring gene dual specificity phosphatase 14 Neighboring gene acetyl-Coenzyme A carboxylase alpha Neighboring gene predicted gene 11437 Neighboring gene 60S ribosomal protein L35 pseudogene

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
chromatin binding IBA
Inferred from Biological aspect of Ancestor
more info
 
contributes_to histone acetyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
contributes_to histone acetyltransferase activity ISO
Inferred from Sequence Orthology
more info
 
transcription coactivator activity IBA
Inferred from Biological aspect of Ancestor
more info
 
transcription factor activity, sequence-specific DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
chromatin remodeling IBA
Inferred from Biological aspect of Ancestor
more info
 
histone H3 acetylation ISO
Inferred from Sequence Orthology
more info
 
histone acetylation IEA
Inferred from Electronic Annotation
more info
 
mitotic nuclear division IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of histone acetylation IBA
Inferred from Biological aspect of Ancestor
more info
 
regulation of histone deacetylation IGI
Inferred from Genetic Interaction
more info
PubMed 
regulation of protein phosphorylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of protein stability IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of transcription from RNA polymerase II promoter IBA
Inferred from Biological aspect of Ancestor
more info
 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
regulation of tubulin deacetylation IGI
Inferred from Genetic Interaction
more info
PubMed 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
Ada2/Gcn5/Ada3 transcription activator complex IDA
Inferred from Direct Assay
more info
PubMed 
PCAF complex ISO
Inferred from Sequence Orthology
more info
 
SAGA-type complex IBA
Inferred from Biological aspect of Ancestor
more info
 
chromosome IEA
Inferred from Electronic Annotation
more info
 
mitotic spindle IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
transcriptional adapter 2-alpha
Names
ADA2-like protein

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_172562.3NP_766150.1  transcriptional adapter 2-alpha

    See identical proteins and their annotated locations for NP_766150.1

    Status: PROVISIONAL

    Source sequence(s)
    AL596447, AL645615
    Consensus CDS
    CCDS25183.1
    UniProtKB/Swiss-Prot
    Q8CHV6
    Related
    ENSMUSP00000018795, OTTMUSP00000000920, ENSMUST00000018795, OTTMUST00000001901
    Conserved Domains (4) summary
    COG5114
    Location:11440
    COG5114; Histone acetyltransferase complex SAGA/ADA, subunit ADA2 [Chromatin structure and dynamics]
    cd00167
    Location:74118
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    cd02335
    Location:1564
    ZZ_ADA2; Zinc finger, ZZ type. Zinc finger present in ADA2, a putative transcriptional adaptor, and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding.
    pfam04433
    Location:364440
    SWIRM; SWIRM domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000077.6 Reference GRCm38.p3 C57BL/6J

    Range
    84078920..84129642 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006532989.2XP_006533052.1  

    Conserved Domains (4) summary
    COG5114
    Location:11420
    COG5114; Histone acetyltransferase complex SAGA/ADA, subunit ADA2 [Chromatin structure and dynamics]
    cd00167
    Location:5498
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    cl00295
    Location:1544
    ZZ; Zinc finger, ZZ type. Zinc finger present in dystrophin, CBP/p300 and many other proteins. The ZZ motif coordinates one or two zinc ions and most likely participates in ligand binding or molecular scaffolding. Many proteins containing ZZ motifs have ...
    pfam04433
    Location:344420
    SWIRM; SWIRM domain
  2. XM_006532991.1XP_006533054.1  

    Conserved Domains (2) summary
    COG5114
    Location:1276
    COG5114; Histone acetyltransferase complex SAGA/ADA, subunit ADA2 [Chromatin structure and dynamics]
    pfam04433
    Location:200276
    SWIRM; SWIRM domain
  3. XM_006532990.2XP_006533053.1  

    Conserved Domains (3) summary
    COG5114
    Location:11304
    COG5114; Histone acetyltransferase complex SAGA/ADA, subunit ADA2 [Chromatin structure and dynamics]
    cd00167
    Location:74118
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    cd02335
    Location:1564
    ZZ_ADA2; Zinc finger, ZZ type. Zinc finger present in ADA2, a putative transcriptional adaptor, and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding.
  4. XM_011248932.1XP_011247234.1  

    Conserved Domains (3) summary
    COG5114
    Location:11272
    COG5114; Histone acetyltransferase complex SAGA/ADA, subunit ADA2 [Chromatin structure and dynamics]
    cd00167
    Location:74118
    SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
    cd02335
    Location:1564
    ZZ_ADA2; Zinc finger, ZZ type. Zinc finger present in ADA2, a putative transcriptional adaptor, and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding.

Alternate Mm_Celera

Genomic

  1. AC_000033.1 Alternate Mm_Celera

    Range
    93684540..93738158 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)