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Gemin5 gem (nuclear organelle) associated protein 5 [ Mus musculus (house mouse) ]

Gene ID: 216766, updated on 8-May-2016
Official Symbol
Gemin5provided by MGI
Official Full Name
gem (nuclear organelle) associated protein 5provided by MGI
Primary source
MGI:MGI:2449311
See related
Ensembl:ENSMUSG00000037275
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
AA407055; AA407208; AI451603; BB194447; C330013N08
Orthologs
Location:
11; 11 B1.3
Exon count:
28
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 11 NC_000077.6 (58120001..58168555, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (57933503..57982041, complement)

Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene predicted gene 12248 Neighboring gene CCR4-NOT transcription complex, subunit 8 Neighboring gene predicted gene 12247 Neighboring gene predicted gene, 33350 Neighboring gene mitochondrial ribosomal protein L22 Neighboring gene predicted gene 12250

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
RNA binding IEA
Inferred from Electronic Annotation
more info
 
poly(A) RNA binding ISO
Inferred from Sequence Orthology
more info
 
snRNA binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
RNA splicing IEA
Inferred from Electronic Annotation
more info
 
mRNA processing IEA
Inferred from Electronic Annotation
more info
 
spliceosomal snRNP assembly ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
SMN complex ISO
Inferred from Sequence Orthology
more info
 
SMN-Sm protein complex ISO
Inferred from Sequence Orthology
more info
 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
cytosol ISO
Inferred from Sequence Orthology
more info
 
membrane ISO
Inferred from Sequence Orthology
more info
 
nuclear body ISO
Inferred from Sequence Orthology
more info
 
nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
nucleus ISO
Inferred from Sequence Orthology
more info
 

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001166669.1NP_001160141.1  gem-associated protein 5 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    AI462876, AK143536, AK162955, AL672182, BY742908
    Consensus CDS
    CCDS48802.1
    UniProtKB/Swiss-Prot
    Q8BX17
    UniProtKB/TrEMBL
    E9PUU4, Q3TR97
    Related
    ENSMUSP00000131842, ENSMUST00000172035
    Conserved Domains (2) summary
    COG2319
    Location:53411
    WD40; WD40 repeat [General function prediction only]
    cl02567
    Location:57408
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  2. NM_001166670.1NP_001160142.1  gem-associated protein 5 isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) uses alternate in-frame splice junctions at the 5' ends of two different exons compared to variant 1. The resulting isoform (3) has the same N- and C-termini but is 2 aa shorter compared to isoform 1.
    Source sequence(s)
    AI462876, AK143536, AK162955, BY742908
    UniProtKB/Swiss-Prot
    Q8BX17
    UniProtKB/TrEMBL
    Q3TR97
    Conserved Domains (3) summary
    PHA02666
    Location:12851468
    PHA02666; hypothetical protein; Provisional
    COG2319
    Location:53410
    WD40; WD40 repeat [General function prediction only]
    cl02567
    Location:57407
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  3. NM_001166671.1NP_001160143.1  gem-associated protein 5 isoform 4

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) uses an alternate splice junction at the 5' end of an exon compared to variant 1, that causes a frameshift. The translation start site is thought to occur downstream of the alternate splice junction, making the resulting isoform (4) shorter at the N-terminus compared to isoform 1.
    Source sequence(s)
    AI462876, AK143536, AK162955, BY742908
    UniProtKB/Swiss-Prot
    Q8BX17
    UniProtKB/TrEMBL
    Q3TR97
    Conserved Domains (3) summary
    PHA02666
    Location:10241207
    PHA02666; hypothetical protein; Provisional
    COG2319
    Location:25448
    WD40; WD40 repeat [General function prediction only]
    cl02567
    Location:67406
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  4. NM_172558.3NP_766146.2  gem-associated protein 5 isoform 2

    See identical proteins and their annotated locations for NP_766146.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice junction at the 5' end of an exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is 1 aa shorter compared to isoform 1.
    Source sequence(s)
    AI462876, AK143536, AK162955, BY742908
    Consensus CDS
    CCDS24723.1
    UniProtKB/Swiss-Prot
    Q8BX17
    UniProtKB/TrEMBL
    Q3TR97
    Related
    ENSMUSP00000036603, OTTMUSP00000005897, ENSMUST00000035604, OTTMUST00000012726
    Conserved Domains (3) summary
    PHA02666
    Location:12861469
    PHA02666; hypothetical protein; Provisional
    COG2319
    Location:53411
    WD40; WD40 repeat [General function prediction only]
    cl02567
    Location:57408
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000077.6 Reference GRCm38.p3 C57BL/6J

    Range
    58120001..58168555 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006532853.2XP_006532916.1  

    Conserved Domains (2) summary
    COG2319
    Location:53410
    WD40; WD40 repeat [General function prediction only]
    cl02567
    Location:57407
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  2. XM_006532852.2XP_006532915.1  

    See identical proteins and their annotated locations for XP_006532915.1

    UniProtKB/TrEMBL
    A2AFQ9
    Related
    ENSMUSP00000099772, OTTMUSP00000005898, ENSMUST00000102711, OTTMUST00000012727
    Conserved Domains (3) summary
    PHA02666
    Location:12851468
    PHA02666; hypothetical protein; Provisional
    COG2319
    Location:53411
    WD40; WD40 repeat [General function prediction only]
    cl02567
    Location:57408
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

Reference GRCm38.p3 CAST/Ei

Genomic

  1. NT_187029.1 Reference GRCm38.p3 CAST/Ei

    Range
    133423..181966
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006537468.2XP_006537531.1  

    Conserved Domains (2) summary
    COG2319
    Location:53411
    WD40; WD40 repeat [General function prediction only]
    cl02567
    Location:57408
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  2. XM_006537470.2XP_006537533.1  

    See identical proteins and their annotated locations for XP_006537533.1

    UniProtKB/TrEMBL
    A2AFQ9
    Conserved Domains (3) summary
    PHA02666
    Location:12851468
    PHA02666; hypothetical protein; Provisional
    COG2319
    Location:53411
    WD40; WD40 repeat [General function prediction only]
    cl02567
    Location:57408
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
  3. XM_006537469.2XP_006537532.1  

    Conserved Domains (2) summary
    COG2319
    Location:53410
    WD40; WD40 repeat [General function prediction only]
    cl02567
    Location:57407
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

Alternate Mm_Celera

Genomic

  1. AC_000033.1 Alternate Mm_Celera

    Range
    62874539..62922743 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)