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Cdc34 cell division cycle 34 [ Mus musculus (house mouse) ]

Gene ID: 216150, updated on 8-May-2016
Official Symbol
Cdc34provided by MGI
Official Full Name
cell division cycle 34provided by MGI
Primary source
MGI:MGI:102657
See related
Ensembl:ENSMUSG00000020307
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
UBE2R1; AI327276
Orthologs
Location:
10 C1; 10 39.72 cM
Exon count:
5
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 10 NC_000076.6 (79682195..79688398)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (79144940..79151143)

Chromosome 10 - NC_000076.6Genomic Context describing neighboring genes Neighboring gene mucosal vascular addressin cell adhesion molecule 1 Neighboring gene tubulin polyglutamylase complex subunit 1 Neighboring gene granzyme M (lymphocyte met-ase 1) Neighboring gene basigin

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Targeted (2) 
  • Herpes simplex infection, organism-specific biosystem (from KEGG)
    Herpes simplex infection, organism-specific biosystemHerpes simplex virus (HSV) infections are very common worldwide, with the prevalence of HSV-1 reaching up to 80%-90%. Primary infection with HSV takes place in the mucosa, followed by the establishme...
  • Herpes simplex infection, conserved biosystem (from KEGG)
    Herpes simplex infection, conserved biosystemHerpes simplex virus (HSV) infections are very common worldwide, with the prevalence of HSV-1 reaching up to 80%-90%. Primary infection with HSV takes place in the mucosa, followed by the establishme...
  • TNF-alpha NF-kB Signaling Pathway, organism-specific biosystem (from WikiPathways)
    TNF-alpha NF-kB Signaling Pathway, organism-specific biosystem
    TNF-alpha NF-kB Signaling Pathway
  • Ubiquitin mediated proteolysis, organism-specific biosystem (from KEGG)
    Ubiquitin mediated proteolysis, organism-specific biosystemProtein ubiquitination plays an important role in eukaryotic cellular processes. It mainly functions as a signal for 26S proteasome dependent protein degradation. The addition of ubiquitin to protein...
  • Ubiquitin mediated proteolysis, conserved biosystem (from KEGG)
    Ubiquitin mediated proteolysis, conserved biosystemProtein ubiquitination plays an important role in eukaryotic cellular processes. It mainly functions as a signal for 26S proteasome dependent protein degradation. The addition of ubiquitin to protein...
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
ubiquitin conjugating enzyme activity IDA
Inferred from Direct Assay
more info
PubMed 
ubiquitin conjugating enzyme activity ISO
Inferred from Sequence Orthology
more info
 
ubiquitin protein ligase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
ubiquitin protein ligase binding IBA
Inferred from Biological aspect of Ancestor
more info
 
ubiquitin-protein transferase activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
cell cycle IEA
Inferred from Electronic Annotation
more info
 
cellular response to interferon-beta ISO
Inferred from Sequence Orthology
more info
 
negative regulation of cAMP-mediated signaling ISO
Inferred from Sequence Orthology
more info
 
positive regulation of inclusion body assembly ISO
Inferred from Sequence Orthology
more info
 
positive regulation of neuron apoptotic process ISO
Inferred from Sequence Orthology
more info
 
proteasome-mediated ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
proteasome-mediated ubiquitin-dependent protein catabolic process ISO
Inferred from Sequence Orthology
more info
 
protein K48-linked ubiquitination ISO
Inferred from Sequence Orthology
more info
 
protein polyubiquitination ISO
Inferred from Sequence Orthology
more info
 
protein ubiquitination ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
nucleus IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
ubiquitin-conjugating enzyme E2 R1
Names
(E3-independent) E2 ubiquitin-conjugating enzyme R1
E2 ubiquitin-conjugating enzyme R1
E2-CDC34
cell division cycle 34 homolog
ubiquitin-conjugating enzyme Cdc34
ubiquitin-conjugating enzyme E2-32 kDa complementing
ubiquitin-conjugating enzyme E2-CDC34
ubiquitin-protein ligase R1
NP_808281.1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_177613.2NP_808281.1  ubiquitin-conjugating enzyme E2 R1

    See identical proteins and their annotated locations for NP_808281.1

    Status: PROVISIONAL

    Source sequence(s)
    BC039160
    Consensus CDS
    CCDS23983.1
    UniProtKB/Swiss-Prot
    Q8CFI2
    Related
    ENSMUSP00000020550, ENSMUST00000020550
    Conserved Domains (2) summary
    COG5078
    Location:6162
    COG5078; Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones]
    cd00195
    Location:11162
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000076.6 Reference GRCm38.p3 C57BL/6J

    Range
    79682195..79688398
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006513483.2XP_006513546.1  

    See identical proteins and their annotated locations for XP_006513546.1

    Conserved Domains (2) summary
    COG5078
    Location:6162
    COG5078; Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones]
    cd00195
    Location:11162
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...
  2. XM_006513482.2XP_006513545.1  

    Conserved Domains (2) summary
    COG5078
    Location:6126
    COG5078; Ubiquitin-protein ligase [Posttranslational modification, protein turnover, chaperones]
    cd00195
    Location:11125
    UBCc; Ubiquitin-conjugating enzyme E2, catalytic (UBCc) domain. This is part of the ubiquitin-mediated protein degradation pathway in which a thiol-ester linkage forms between a conserved cysteine and the C-terminus of ubiquitin and complexes with ubiquitin ...

Alternate Mm_Celera

Genomic

  1. AC_000032.1 Alternate Mm_Celera

    Range
    80696643..80702713
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)