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Hip1 huntingtin interacting protein 1 [ Mus musculus (house mouse) ]

Gene ID: 215114, updated on 28-May-2016
Official Symbol
Hip1provided by MGI
Official Full Name
huntingtin interacting protein 1provided by MGI
Primary source
MGI:MGI:1099804
See related
Ensembl:ENSMUSG00000039959 Vega:OTTMUSG00000055920
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
mKIAA4113; 2610109B09Rik; A930014B11Rik; E130315I21Rik
Orthologs
Location:
5 75.18 cM; 5 F-G2
Exon count:
35
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 5 NC_000071.6 (135406518..135545319, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (135882388..136020992, complement)

Chromosome 5 - NC_000071.6Genomic Context describing neighboring genes Neighboring gene NOL1/NOP2/Sun domain family, member 5 Neighboring gene nuclear pore membrane protein 121 Neighboring gene microRNA 7033 Neighboring gene predicted gene, 40344 Neighboring gene predicted gene, 40343 Neighboring gene chemokine (C-C motif) ligand 26 Neighboring gene chemokine (C-C motif) ligand 24

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • EGFR1 Signaling Pathway, organism-specific biosystem (from WikiPathways)
    EGFR1 Signaling Pathway, organism-specific biosystemThe androgen receptor is a member of the nuclear receptor family of ligand activated transcription factors. These receptors bind to steroid hormones, thyroid hormone, retinoids and vitamin D among ot...
  • Huntington's disease, organism-specific biosystem (from KEGG)
    Huntington's disease, organism-specific biosystemHuntington disease (HD) is an autosomal-dominant neurodegenerative disorder that primarily affects medium spiny striatal neurons (MSN). The symptoms are choreiform, involuntary movements, personality...
  • Huntington's disease, conserved biosystem (from KEGG)
    Huntington's disease, conserved biosystemHuntington disease (HD) is an autosomal-dominant neurodegenerative disorder that primarily affects medium spiny striatal neurons (MSN). The symptoms are choreiform, involuntary movements, personality...
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • KIAA4113, MGC27616

Gene Ontology Provided by MGI

Function Evidence Code Pubs
actin binding IEA
Inferred from Electronic Annotation
more info
 
clathrin binding ISO
Inferred from Sequence Orthology
more info
PubMed 
phosphatidylinositol binding ISO
Inferred from Sequence Orthology
more info
 
phospholipid binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
activation of cysteine-type endopeptidase activity involved in apoptotic process ISO
Inferred from Sequence Orthology
more info
PubMed 
apoptotic process ISO
Inferred from Sequence Orthology
more info
PubMed 
apoptotic signaling pathway ISO
Inferred from Sequence Orthology
more info
 
cell differentiation IEA
Inferred from Electronic Annotation
more info
 
clathrin coat assembly ISO
Inferred from Sequence Orthology
more info
PubMed 
clathrin-mediated endocytosis IEA
Inferred from Electronic Annotation
more info
 
endocytosis IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of receptor-mediated endocytosis IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of receptor-mediated endocytosis ISO
Inferred from Sequence Orthology
more info
 
regulation of apoptotic process ISO
Inferred from Sequence Orthology
more info
PubMed 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
Golgi apparatus ISO
Inferred from Sequence Orthology
more info
PubMed 
clathrin-coated vesicle ISO
Inferred from Sequence Orthology
more info
PubMed 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
 
intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
nucleus IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
huntingtin-interacting protein 1
Names
HIP-I
hip1
huntingtin-interacting protein I

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_146001.2NP_666113.2  huntingtin-interacting protein 1

    See identical proteins and their annotated locations for NP_666113.2

    Status: VALIDATED

    Source sequence(s)
    AK147246, BC017516, BY309818, CF746398
    Consensus CDS
    CCDS51663.1
    UniProtKB/Swiss-Prot
    Q8VD75
    Related
    ENSMUSP00000059033, OTTMUSP00000072737, ENSMUST00000060311, OTTMUST00000138327
    Conserved Domains (2) summary
    smart00307
    Location:8061004
    ILWEQ; I/LWEQ domain
    pfam07651
    Location:37308
    ANTH; ANTH domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000071.6 Reference GRCm38.p3 C57BL/6J

    Range
    135406518..135545319 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011240878.1XP_011239180.1  

    See identical proteins and their annotated locations for XP_011239180.1

    UniProtKB/Swiss-Prot
    Q8VD75
    Conserved Domains (2) summary
    smart00307
    Location:8061004
    ILWEQ; I/LWEQ domain
    pfam07651
    Location:37308
    ANTH; ANTH domain
  2. XM_011240879.1XP_011239181.1  

    Conserved Domains (2) summary
    smart00307
    Location:781979
    ILWEQ; I/LWEQ domain
    cd03564
    Location:15128
    ANTH_AP180_CALM; ANTH domain family; composed of adaptor protein 180 (AP180), clathrin assembly lymphoid myeloid leukemia protein (CALM) and similar proteins. A set of proteins previously designated as harboring an ENTH domain in fact contains a highly similar, yet ...
  3. XM_006504415.2XP_006504478.1  

    See identical proteins and their annotated locations for XP_006504478.1

    Conserved Domains (2) summary
    smart00307
    Location:772970
    ILWEQ; I/LWEQ domain
    cd03564
    Location:6119
    ANTH_AP180_CALM; ANTH domain family; composed of adaptor protein 180 (AP180), clathrin assembly lymphoid myeloid leukemia protein (CALM) and similar proteins. A set of proteins previously designated as harboring an ENTH domain in fact contains a highly similar, yet ...

RNA

  1. XR_868560.1 RNA Sequence

Alternate Mm_Celera

Genomic

  1. AC_000027.1 Alternate Mm_Celera

    Range
    132418220..132556655 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)