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Taldo1 transaldolase 1 [ Mus musculus (house mouse) ]

Gene ID: 21351, updated on 8-May-2016
Official Symbol
Taldo1provided by MGI
Official Full Name
transaldolase 1provided by MGI
Primary source
MGI:MGI:1274789
See related
Ensembl:ENSMUSG00000025503 Vega:OTTMUSG00000027257
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Summary
This gene encodes a key enzyme of the nonoxidative pentose phosphate pathway that provides ribose-5-phosphate for nucleic acid synthesis and nicotinamide adenine dinucleotide phosphate (NADPH) for lipid biosynthesis. The encoded protein is important for maintaining structure and function of mitochondria. Studies in knockout mice identify that deficiency of this gene product is a cause of sperm dysmotility and male infertility. Deficiency of this protein has also been identified as a cause of hepatocarcinogenesis in mice. Two related pseudogenes have been identified on chromosome 10. [provided by RefSeq, Mar 2010]
Orthologs
Location:
7; 7 F3-F4
Exon count:
8
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 7 NC_000073.6 (141392160..141402976)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (148578059..148588875)

Chromosome 7 - NC_000073.6Genomic Context describing neighboring genes Neighboring gene deformed epidermal autoregulatory factor 1 (Drosophila) Neighboring gene transmembrane protein 80 Neighboring gene EPS8-like 2 Neighboring gene RIKEN cDNA B230206H07 gene Neighboring gene RAN guanine nucleotide release factor pseudogene Neighboring gene Parkinson disease 7 domain containing 1

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
carbohydrate binding ISO
Inferred from Sequence Orthology
more info
 
catalytic activity IEA
Inferred from Electronic Annotation
more info
 
monosaccharide binding ISO
Inferred from Sequence Orthology
more info
 
sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity ISO
Inferred from Sequence Orthology
more info
 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
carbohydrate metabolic process IEA
Inferred from Electronic Annotation
more info
 
fructose 6-phosphate metabolic process ISO
Inferred from Sequence Orthology
more info
 
glyceraldehyde-3-phosphate metabolic process ISO
Inferred from Sequence Orthology
more info
 
pentose-phosphate shunt ISO
Inferred from Sequence Orthology
more info
 
pentose-phosphate shunt, non-oxidative branch ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytosol ISO
Inferred from Sequence Orthology
more info
 
extracellular exosome ISO
Inferred from Sequence Orthology
more info
 
intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
 
nucleus ISO
Inferred from Sequence Orthology
more info
 

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_011528.4NP_035658.1  transaldolase

    See identical proteins and their annotated locations for NP_035658.1

    Status: REVIEWED

    Source sequence(s)
    AC163434
    Consensus CDS
    CCDS22011.1
    UniProtKB/Swiss-Prot
    Q93092
    Related
    ENSMUSP00000026576, OTTMUSP00000033905, ENSMUST00000026576, OTTMUST00000067396
    Conserved Domains (2) summary
    cd00957
    Location:13326
    Transaldolase_TalAB; Transaldolases including both TalA and TalB
    PTZ00411
    Location:11330
    PTZ00411; transaldolase-like protein; Provisional

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000073.6 Reference GRCm38.p3 C57BL/6J

    Range
    141392160..141402976
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000029.1 Alternate Mm_Celera

    Range
    141185913..141196721
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)