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Iglon5 IgLON family member 5 [ Mus musculus (house mouse) ]

Gene ID: 210094, updated on 23-Mar-2024

Summary

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Official Symbol
Iglon5provided by MGI
Official Full Name
IgLON family member 5provided by MGI
Primary source
MGI:MGI:2686277
See related
Ensembl:ENSMUSG00000013367 AllianceGenome:MGI:2686277
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm1431; A230106M20Rik
Summary
Predicted to be located in extracellular region. Is expressed in central nervous system; ganglia; and neural retina. Orthologous to human IGLON5 (IgLON family member 5). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in whole brain E14.5 (RPKM 27.1), CNS E14 (RPKM 23.2) and 14 other tissues See more
Orthologs
human all
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Genomic context

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See Iglon5 in Genome Data Viewer
Location:
7 B3; 7 28.25 cM
Exon count:
8
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (43122325..43139635, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (43472901..43490211, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene electron transferring flavoprotein, beta polypeptide Neighboring gene microRNA 7051 Neighboring gene STARR-positive B cell enhancer ABC_E4923 Neighboring gene predicted gene, 39000 Neighboring gene V-set and immunoglobulin domain containing 10 like Neighboring gene Siglec family like 2 Neighboring gene predicted gene 9278

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Spatiotemporal expression of IgLON family members in the developing mouse nervous system. Fearnley S, et al. Sci Rep, 2021 Oct 1. PMID 34599206, Free PMC Article
  2. Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion. Gu Z, et al. PLoS One, 2015. PMID 25826454, Free PMC Article
  3. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
  4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
  5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

See all (11) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. IgLON5 deficiency produces behavioral alterations in a knockout mouse model.
    Title: IgLON5 deficiency produces behavioral alterations in a knockout mouse model.
Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (4) 

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
igLON family member 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001164518.2 → NP_001157990.1  igLON family member 5 precursor

    See identical proteins and their annotated locations for NP_001157990.1

    Status: VALIDATED

    Source sequence(s)
    AC154108
    Consensus CDS
    CCDS52223.1
    UniProtKB/Swiss-Prot
    A7E1X9, Q8HW98
    Related
    ENSMUSP00000103608.2, ENSMUST00000107974.3
    Conserved Domains (3) summary
    pfam13927
    Location:217 → 295
    Ig_3; Immunoglobulin domain
    cd00096
    Location:41 → 46
    Ig; Ig strand A' [structural motif]
    cl11960
    Location:41 → 129
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    43122325..43139635 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_003946429.1 RNA Sequence

  2. XR_003946430.1 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8HW98.2 GenPept UniProtKB/Swiss-Prot:Q8HW98

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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