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Vamp7 vesicle-associated membrane protein 7 [ Mus musculus (house mouse) ]

Gene ID: 20955, updated on 8-May-2016
Official Symbol
Vamp7provided by MGI
Official Full Name
vesicle-associated membrane protein 7provided by MGI
Primary source
MGI:MGI:1096399
See related
Ensembl:ENSMUSG00000051412
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Sybl1; VAMP-7; TI-VAMP
Orthologs
Location:
X; X
Exon count:
8
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) X Unlocalized Scaffold NT_165789.2 (10737..39191, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) X Unlocalized Scaffold NT_165789.2 (10738..39148, complement)

NT_165789.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105243599 Neighboring gene sprouty homolog 3 (Drosophila) Neighboring gene trimethyllysine hydroxylase, epsilon Neighboring gene RAD9-HUS1-RAD1 interacting nuclear orphan 1 pseudogene

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
SNAP receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
SNAP receptor activity ISO
Inferred from Sequence Orthology
more info
 
SNARE binding IBA
Inferred from Biological aspect of Ancestor
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
syntaxin binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
ER to Golgi vesicle-mediated transport ISO
Inferred from Sequence Orthology
more info
 
ER to Golgi vesicle-mediated transport ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
Golgi to plasma membrane protein transport IMP
Inferred from Mutant Phenotype
more info
PubMed 
SNARE complex assembly IDA
Inferred from Direct Assay
more info
PubMed 
calcium ion regulated exocytosis ISO
Inferred from Sequence Orthology
more info
 
calcium ion regulated exocytosis ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
endocytosis IBA
Inferred from Biological aspect of Ancestor
more info
 
endosome to lysosome transport IBA
Inferred from Biological aspect of Ancestor
more info
 
endosome to lysosome transport ISO
Inferred from Sequence Orthology
more info
 
endosome to lysosome transport ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
eosinophil degranulation ISO
Inferred from Sequence Orthology
more info
 
eosinophil degranulation ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
exocytosis IBA
Inferred from Biological aspect of Ancestor
more info
 
exocytosis ISO
Inferred from Sequence Orthology
more info
 
natural killer cell degranulation ISO
Inferred from Sequence Orthology
more info
 
neutrophil degranulation ISO
Inferred from Sequence Orthology
more info
 
neutrophil degranulation ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
phagocytosis, engulfment ISO
Inferred from Sequence Orthology
more info
 
phagocytosis, engulfment ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
positive regulation of dendrite morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of histamine secretion by mast cell ISO
Inferred from Sequence Orthology
more info
 
protein transport IEA
Inferred from Electronic Annotation
more info
 
regulation of protein targeting to vacuolar membrane IMP
Inferred from Mutant Phenotype
more info
PubMed 
transport IEA
Inferred from Electronic Annotation
more info
 
triglyceride transport ISO
Inferred from Sequence Orthology
more info
 
vesicle fusion ISO
Inferred from Sequence Orthology
more info
 
vesicle fusion ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
vesicle fusion with Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
vesicle transport along microtubule ISO
Inferred from Sequence Orthology
more info
 
vesicle-mediated transport ISO
Inferred from Sequence Orthology
more info
 
vesicle-mediated transport ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
Component Evidence Code Pubs
Golgi apparatus IDA
Inferred from Direct Assay
more info
PubMed 
SNARE complex IBA
Inferred from Biological aspect of Ancestor
more info
 
SNARE complex ISO
Inferred from Sequence Orthology
more info
PubMed 
SNARE complex ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
apical part of cell IDA
Inferred from Direct Assay
more info
PubMed 
azurophil granule membrane ISO
Inferred from Sequence Orthology
more info
 
cell junction IEA
Inferred from Electronic Annotation
more info
 
cell surface IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
 
endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
endoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
 
endoplasmic reticulum membrane ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
endosome IEA
Inferred from Electronic Annotation
more info
 
extracellular exosome ISO
Inferred from Sequence Orthology
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
 
lamellipodium IDA
Inferred from Direct Assay
more info
PubMed 
lamellipodium ISO
Inferred from Sequence Orthology
more info
 
late endosome membrane ISO
Inferred from Sequence Orthology
more info
 
late endosome membrane ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
lysosomal membrane ISO
Inferred from Sequence Orthology
more info
 
lysosomal membrane ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
lysosome IEA
Inferred from Electronic Annotation
more info
 
membrane ISO
Inferred from Sequence Orthology
more info
 
neuron projection IDA
Inferred from Direct Assay
more info
PubMed 
neuron projection ISO
Inferred from Sequence Orthology
more info
 
perinuclear region of cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
phagocytic vesicle IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 
platelet alpha granule ISO
Inferred from Sequence Orthology
more info
 
pseudopodium IDA
Inferred from Direct Assay
more info
PubMed 
pseudopodium ISO
Inferred from Sequence Orthology
more info
 
secretory granule ISO
Inferred from Sequence Orthology
more info
 
secretory granule membrane ISO
Inferred from Sequence Orthology
more info
 
synapse IEA
Inferred from Electronic Annotation
more info
 
trans-Golgi network ISO
Inferred from Sequence Orthology
more info
 
transport vesicle IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
vesicle-associated membrane protein 7
Names
synaptobrevin like 1
synaptobrevin-like protein 1
tetanus neurotoxin-insensitive vesicle-associated membrane protein

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001302138.1NP_001289067.1  vesicle-associated membrane protein 7 isoform 2

    See identical proteins and their annotated locations for NP_001289067.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate splice site in the 5' coding region, and initiates translation at a downstream start codon, compared to variant 1. The resulting isoform (2) has a shorter and distinct N-terminus, compared to isoform 1.
    Source sequence(s)
    AK002825, AK165299, BP768744
    UniProtKB/Swiss-Prot
    P70280
    Conserved Domains (3) summary
    pfam00957
    Location:83151
    Synaptobrevin; Synaptobrevin
    pfam13774
    Location:1170
    Longin; Regulated-SNARE-like domain
    cd15871
    Location:85149
    R-SNARE_VAMP7; SNARE motif of VAMP7
  2. NM_011515.5NP_035645.1  vesicle-associated membrane protein 7 isoform 1

    See identical proteins and their annotated locations for NP_035645.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AK002825, AK165299, BP768744
    UniProtKB/Swiss-Prot
    P70280
    Related
    ENSMUSP00000052262, ENSMUST00000051100
    Conserved Domains (3) summary
    pfam00957
    Location:122190
    Synaptobrevin; Synaptobrevin
    pfam13774
    Location:28109
    Longin; Regulated-SNARE-like domain
    cd15871
    Location:124188
    R-SNARE_VAMP7; SNARE motif of VAMP7

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NT_165789.2 Reference GRCm38.p3 C57BL/6J

    Range
    10737..39191 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006535856.2XP_006535919.1  

    Conserved Domains (2) summary
    pfam00957
    Location:2189
    Synaptobrevin; Synaptobrevin
    cd15871
    Location:2387
    R-SNARE_VAMP7; SNARE motif of VAMP7
  2. XM_011249809.1XP_011248111.1  

    See identical proteins and their annotated locations for XP_011248111.1

    Conserved Domains (3) summary
    pfam00957
    Location:83151
    Synaptobrevin; Synaptobrevin
    pfam13774
    Location:1170
    Longin; Regulated-SNARE-like domain
    cd15871
    Location:85149
    R-SNARE_VAMP7; SNARE motif of VAMP7

Alternate Mm_Celera

Genomic

  1. NW_001031675.1 Alternate Mm_Celera

    Range
    326197..354678
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)