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Btla B and T lymphocyte associated [ Mus musculus (house mouse) ]

Gene ID: 208154, updated on 8-May-2016
Official Symbol
Btlaprovided by MGI
Official Full Name
B and T lymphocyte associatedprovided by MGI
Primary source
MGI:MGI:2658978
See related
Ensembl:ENSMUSG00000052013 Vega:OTTMUSG00000014972
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
A630002H24
Orthologs
Location:
16; 16 B5
Exon count:
6
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 16 NC_000082.6 (45223547..45252895)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 16 NC_000082.5 (45224450..45253008)

Chromosome 16 - NC_000082.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 41456 Neighboring gene predicted gene 6030 Neighboring gene predicted gene, 30636 Neighboring gene predicted gene, 30760

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • MGC124217, MGC124218

Gene Ontology Provided by MGI

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
receptor activity IGI
Inferred from Genetic Interaction
more info
PubMed 
Process Evidence Code Pubs
adaptive immune response IEA
Inferred from Electronic Annotation
more info
 
cell surface receptor signaling pathway IDA
Inferred from Direct Assay
more info
PubMed 
immune response-regulating cell surface receptor signaling pathway IMP
Inferred from Mutant Phenotype
more info
PubMed 
immune system process IEA
Inferred from Electronic Annotation
more info
 
negative regulation of B cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of T cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of alpha-beta T cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
external side of plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
integral component of plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
membrane IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
B- and T-lymphocyte attenuator
Names
B and T lymphocyte attenuator
B- and T-lymphocyte-associated protein

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001037719.2NP_001032808.2  B- and T-lymphocyte attenuator isoform 1 precursor

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer transcript and it encodes the longer protein (isoform 1).
    Source sequence(s)
    AK041334, BB123968, BC108964
    Consensus CDS
    CCDS28195.1
    UniProtKB/Swiss-Prot
    Q7TSA3
    UniProtKB/TrEMBL
    E9QNY6, Q32MV8
    Related
    ENSMUSP00000067877, ENSMUST00000063654
    Conserved Domains (2) summary
    cd00096
    Location:61139
    Ig; Immunoglobulin domain
    smart00410
    Location:50142
    IG_like; Immunoglobulin like
  2. NM_177584.3NP_808252.1  B- and T-lymphocyte attenuator isoform 2 precursor

    See identical proteins and their annotated locations for NP_808252.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1, resulting in a shorter protein (isoform 2).
    Source sequence(s)
    AK041334, BB123968
    Consensus CDS
    CCDS28196.1
    UniProtKB/Swiss-Prot
    Q7TSA3
    UniProtKB/TrEMBL
    A0A0R4J1A0
    Related
    ENSMUSP00000099866, OTTMUSP00000015921, ENSMUST00000102802, OTTMUST00000035544
    Conserved Domains (2) summary
    cd00096
    Location:61139
    Ig; Immunoglobulin domain
    smart00410
    Location:50142
    IG_like; Immunoglobulin like

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000082.6 Reference GRCm38.p3 C57BL/6J

    Range
    45223547..45252895
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006521909.2XP_006521972.1  

    Conserved Domains (2) summary
    cd00096
    Location:61139
    Ig; Immunoglobulin domain
    smart00410
    Location:50142
    IG_like; Immunoglobulin like
  2. XM_006521907.2XP_006521970.1  

  3. XM_006521908.2XP_006521971.1  

Alternate Mm_Celera

Genomic

  1. AC_000038.1 Alternate Mm_Celera

    Range
    45615691..45643124
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)