Srp14 signal recognition particle 14 [Mus musculus (house mouse)] - Gene

Summary

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Official Symbol: Srp14provided by MGI
Official Full Name: signal recognition particle 14provided by MGI
Primary source: MGI:107169
Locus tag: RP23-450P9.3
See related: Ensembl:ENSMUSG00000009549; Vega:OTTMUSG00000015233
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 14kDa; AW536328

Genomic context

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Location :: 2 E5; 2

Sequence :: Chromosome: 2; NC_000068.7 (118475843..118479696, complement)

See Srp14 in Epigenomics, MapViewer

Chromosome 2 - NC_000068.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence

Go to nucleotideGraphics FASTA GenBank

Go to reference sequence details

Bibliography

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GeneRIFs: Gene References Into Functions What's a GeneRIF?

Submit: New GeneRIF Correction

Pathways from BioSystems

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Gene Expression, organism-specific biosystem (from REACTOME)
Gene Expression, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Metabolism of proteins, organism-specific biosystem (from REACTOME)
Metabolism of proteins, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Protein export, organism-specific biosystem (from KEGG)
Protein export, organism-specific biosystemThe protein export is the active transport of proteins from the cytoplasm to the exterior of the cell, or to the periplasmic compartment in Gram-negative bacteria. The sec dependent pathway is the ge...
Protein export, conserved biosystem (from KEGG)
Protein export, conserved biosystemThe protein export is the active transport of proteins from the cytoplasm to the exterior of the cell, or to the periplasmic compartment in Gram-negative bacteria. The sec dependent pathway is the ge...
SRP-dependent cotranslational protein targeting to membrane, organism-specific biosystem (from REACTOME)
SRP-dependent cotranslational protein targeting to membrane, organism-specific biosystemcomputationally inferred pathway (not manually curated)
Translation, organism-specific biosystem (from REACTOME)
Translation, organism-specific biosystemcomputationally inferred pathway (not manually curated)
mRNA processing, organism-specific biosystem (from WikiPathways)
mRNA processing, organism-specific biosystemAdapted from Reactome, see: [http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_1675.1 REACT 1675.1] This process describes the conversion of precursor messenger RNA into mature messenge...

General gene information

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Markers

Srp14 (e-PCR), detects polymorphism
- UniSTS:536606

Srp14 (e-PCR), detects polymorphism
- UniSTS:536607

AW536328 (e-PCR)
- UniSTS:178678

Homology

Homologs of the Srp14 gene: The Srp14 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, rat, chicken, and zebrafish.
Map Viewer (Human, Rat)

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
7S RNA binding	IEA Inferred from Electronic Annotation more info
RNA binding	IEA Inferred from Electronic Annotation more info
endoplasmic reticulum signal peptide binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
SRP-dependent cotranslational protein targeting to membrane	IEA Inferred from Electronic Annotation more info
protein targeting to ER	ISO Inferred from Sequence Orthology more info
response to drug	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
cytoplasm	IEA Inferred from Electronic Annotation more info
ribonucleoprotein complex	IEA Inferred from Electronic Annotation more info
signal recognition particle	IEA Inferred from Electronic Annotation more info
signal recognition particle, endoplasmic reticulum targeting	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: signal recognition particle 14 kDa protein

Names: signal recognition particle 14 kDa protein; homologous Alu RNA-binding protein; (homologous Alu RNA binding protein)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_009273.4 → NP_033299.1 signal recognition particle 14 kDa protein

Status: VALIDATED

Source sequence(s)

AK019310, AV338114, BB848168, CD774307

Consensus CDS

CCDS16577.1

UniProtKB/Swiss-Prot

P16254

Related

ENSMUSP00000009693, OTTMUSP00000016215, ENSMUST00000009693, OTTMUST00000036088

Conserved Domains (1) summary

pfam02290
Location:4 – 94
Blast Score: 353

SRP14; Signal recognition particle 14kD protein

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 103

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p1 C57BL/6J

Genomic

NC_000068.7 Reference GRCm38.p1 C57BL/6J

Range

118475843..118479696, complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

AC_000024.1 Alternate Mm_Celera

Range

119626985..119630838, complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

Nucleotide		Protein	Strain
Heading	Accession and Version	Protein	Strain
genomic	AAHY01019943.1 (93123..96976)	None
genomic	AL929163.5 (152339..156192)	None
genomic	CH466519.1	EDL27908.1	mixed
		EDL27909.1	mixed
mRNA	AK019310.1	BAB31658.1	C57BL/6J
mRNA	AK156845.1	BAE33873.1	NOD
mRNA	AK167821.1	BAE39844.1	BALB/c
mRNA	AK168144.1	BAE40110.1	BALB/c
mRNA	AV338114.1	None	C57BL/6J
mRNA	BB848168.1	None
mRNA	BC021537.1	AAH21537.1	FVB/N
mRNA	CD774307.1	None	C57BL/6J
mRNA	M29264.1	AAA40136.1