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Son Son DNA binding protein [ Mus musculus (house mouse) ]

Gene ID: 20658, updated on 28-May-2016
Official Symbol
Sonprovided by MGI
Official Full Name
Son DNA binding proteinprovided by MGI
Primary source
MGI:MGI:98353
See related
Ensembl:ENSMUSG00000022961 Vega:OTTMUSG00000028340
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
nrebp; C81487; AA409051; AU067731; mKIAA1019; 2900011L12Rik
Orthologs
Location:
16 C3.3; 16 53.22 cM
Exon count:
16
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 16 NC_000082.6 (91647824..91679195)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 16 NC_000082.5 (91648069..91679437)

Chromosome 16 - NC_000082.6Genomic Context describing neighboring genes Neighboring gene DnaJ heat shock protein family (Hsp40) member C28 Neighboring gene phosphoribosylglycinamide formyltransferase Neighboring gene predicted gene, 36712 Neighboring gene downstream neighbor of SON Neighboring gene predicted gene 10785 Neighboring gene crystallin, zeta (quinone reductase)-like 1 Neighboring gene intersectin 1 (SH3 domain protein 1A)

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • mRNA processing, organism-specific biosystem (from WikiPathways)
    mRNA processing, organism-specific biosystemAdapted from Reactome, see: [http://www.reactome.org/cgi-bin/eventbrowser_st_id?ST_ID=REACT_1675.1 REACT 1675.1] This process describes the conversion of precursor messenger RNA into mature messenge...
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
DNA binding IEA
Inferred from Electronic Annotation
more info
 
RNA binding ISO
Inferred from Sequence Orthology
more info
 
RS domain binding IPI
Inferred from Physical Interaction
more info
PubMed 
nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
poly(A) RNA binding ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
RNA splicing IEA
Inferred from Electronic Annotation
more info
 
cell cycle IEA
Inferred from Electronic Annotation
more info
 
cytokinesis ISO
Inferred from Sequence Orthology
more info
 
mRNA processing ISO
Inferred from Sequence Orthology
more info
 
microtubule cytoskeleton organization ISO
Inferred from Sequence Orthology
more info
 
negative regulation of apoptotic process ISO
Inferred from Sequence Orthology
more info
 
regulation of RNA splicing ISO
Inferred from Sequence Orthology
more info
 
regulation of cell cycle ISO
Inferred from Sequence Orthology
more info
 
regulation of transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
transcription, DNA-templated IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
nuclear speck ISO
Inferred from Sequence Orthology
more info
 
nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
nucleus IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
protein SON
Names
NRE-binding protein
Son cell proliferation protein
negative regulatory element-binding protein

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_019973.2NP_064357.2  protein SON isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks multiple 3' coding exons and contains an alternate 3' exon, resulting in a distinct 3' coding region and 3' UTR, compared to variant 1. It encodes isoform 2 which is shorter and has a distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AC131691, AK040621, BC061113, BG229132, CJ088081
    Consensus CDS
    CCDS37400.1
    UniProtKB/TrEMBL
    Q8C9T5
    Related
    ENSMUSP00000109670, OTTMUSP00000035761, ENSMUST00000114036, OTTMUST00000070237
    Conserved Domains (1) summary
    pfam08430
    Location:10111137
    Fork_head_N; Forkhead N-terminal region
  2. NM_178880.4NP_849211.3  protein SON isoform 1

    See identical proteins and their annotated locations for NP_849211.3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AC131691, AK040621, AK122418, BC061113, CB849818, CJ088081
    Consensus CDS
    CCDS37399.1
    UniProtKB/Swiss-Prot
    Q9QX47
    UniProtKB/TrEMBL
    Q80TM4, Q8C9T5
    Related
    ENSMUSP00000109671, OTTMUSP00000045712, ENSMUST00000114037, OTTMUST00000084749
    Conserved Domains (3) summary
    cd00048
    Location:23892426
    DSRM; Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III, ...
    pfam01585
    Location:23232366
    G-patch; G-patch domain
    pfam08430
    Location:10111137
    Fork_head_N; Forkhead N-terminal region

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000082.6 Reference GRCm38.p3 C57BL/6J

    Range
    91647824..91679195
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006522969.2XP_006523032.1  

    UniProtKB/TrEMBL
    H9KV00
    Related
    ENSMUSP00000112453, OTTMUSP00000035760, ENSMUST00000117633, OTTMUST00000070236
    Conserved Domains (3) summary
    cd00048
    Location:23892457
    DSRM; Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III, ...
    pfam01585
    Location:23232366
    G-patch; G-patch domain
    pfam08430
    Location:10111137
    Fork_head_N; Forkhead N-terminal region
  2. XM_006522970.2XP_006523033.1  

    Conserved Domains (3) summary
    cd00048
    Location:23592427
    DSRM; Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III, ...
    pfam01585
    Location:22932336
    G-patch; G-patch domain
    pfam08430
    Location:9811107
    Fork_head_N; Forkhead N-terminal region
  3. XM_006522972.2XP_006523035.1  

    UniProtKB/TrEMBL
    H9KV15
    Related
    ENSMUSP00000122320, OTTMUSP00000035764, ENSMUST00000140312, OTTMUST00000070240
    Conserved Domains (1) summary
    pfam08430
    Location:10111137
    Fork_head_N; Forkhead N-terminal region
  4. XM_006522971.2XP_006523034.1  

    Conserved Domains (1) summary
    pfam08430
    Location:10111137
    Fork_head_N; Forkhead N-terminal region
  5. XM_011246107.1XP_011244409.1  

    Conserved Domains (1) summary
    pfam08430
    Location:10111137
    Fork_head_N; Forkhead N-terminal region
  6. XM_006522973.1XP_006523036.1  

    UniProtKB/TrEMBL
    H9KV01
    Related
    ENSMUSP00000113129, OTTMUSP00000035762, ENSMUST00000119368, OTTMUST00000070238
    Conserved Domains (1) summary
    pfam08430
    Location:10111137
    Fork_head_N; Forkhead N-terminal region
  7. XM_011246108.1XP_011244410.1  

    Conserved Domains (3) summary
    cd00048
    Location:20402108
    DSRM; Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III, ...
    pfam01585
    Location:19742017
    G-patch; G-patch domain
    pfam08430
    Location:662788
    Fork_head_N; Forkhead N-terminal region

RNA

  1. XR_384932.2 RNA Sequence

  2. XR_384933.2 RNA Sequence

  3. XR_384934.2 RNA Sequence

  4. XR_384935.2 RNA Sequence

Alternate Mm_Celera

Genomic

  1. AC_000038.1 Alternate Mm_Celera

    Range
    92724593..92757782
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)