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Snap23 synaptosomal-associated protein 23 [ Mus musculus (house mouse) ]

Gene ID: 20619, updated on 15-May-2016
Official Symbol
Snap23provided by MGI
Official Full Name
synaptosomal-associated protein 23provided by MGI
Primary source
MGI:MGI:109356
See related
Ensembl:ENSMUSG00000027287 Vega:OTTMUSG00000015619
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Sndt; 23kDa; Syndet; SNAP-23; AA408749
Orthologs
Location:
2 60.37 cM; 2 E5
Exon count:
11
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 2 NC_000068.7 (120567651..120601255)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (120393407..120426458)

Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4931402G19 gene Neighboring gene calpain 3 Neighboring gene zinc finger protein 106 Neighboring gene leucine rich repeat containing 57 Neighboring gene HAUS augmin-like complex, subunit 2 Neighboring gene START domain containing 9 Neighboring gene kinesin family member 16B pseudogene

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
SNAP receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
SNAP receptor activity ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
syntaxin binding IBA
Inferred from Biological aspect of Ancestor
more info
 
syntaxin binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
exocytosis IMP
Inferred from Mutant Phenotype
more info
PubMed 
histamine secretion by mast cell ISO
Inferred from Sequence Orthology
more info
 
membrane fusion ISO
Inferred from Sequence Orthology
more info
 
protein complex assembly ISO
Inferred from Sequence Orthology
more info
 
protein transport ISO
Inferred from Sequence Orthology
more info
 
regulation of exocytosis ISO
Inferred from Sequence Orthology
more info
 
synaptic vesicle fusion to presynaptic active zone membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
synaptic vesicle priming IBA
Inferred from Biological aspect of Ancestor
more info
 
transport IEA
Inferred from Electronic Annotation
more info
 
vesicle-mediated transport ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
SNARE complex IBA
Inferred from Biological aspect of Ancestor
more info
 
SNARE complex IDA
Inferred from Direct Assay
more info
PubMed 
SNARE complex ISO
Inferred from Sequence Orthology
more info
 
azurophil granule ISO
Inferred from Sequence Orthology
more info
 
cell junction IEA
Inferred from Electronic Annotation
more info
 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
cytoplasmic vesicle IDA
Inferred from Direct Assay
more info
PubMed 
extracellular exosome ISO
Inferred from Sequence Orthology
more info
 
focal adhesion ISO
Inferred from Sequence Orthology
more info
 
mast cell granule ISO
Inferred from Sequence Orthology
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
neuron projection IEA
Inferred from Electronic Annotation
more info
 
nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 
specific granule ISO
Inferred from Sequence Orthology
more info
 
synapse IEA
Inferred from Electronic Annotation
more info
 
terminal bouton ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
synaptosomal-associated protein 23
Names
synaptosomal-associated protein, 23kD
vesicle-membrane fusion protein SNAP-23

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001177792.1NP_001171263.1  synaptosomal-associated protein 23 isoform a

    See identical proteins and their annotated locations for NP_001171263.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and it encodes the longer protein (isoform a).
    Source sequence(s)
    AK017311, AK019162
    Consensus CDS
    CCDS50681.1
    UniProtKB/Swiss-Prot
    O09044
    UniProtKB/TrEMBL
    Q9D3L3
    Related
    ENSMUSP00000112138, OTTMUSP00000016634, ENSMUST00000116437, OTTMUST00000037102
    Conserved Domains (3) summary
    pfam00835
    Location:100157
    SNAP-25; SNAP-25 family
    cd15884
    Location:159217
    SNARE_SNAP23C; C-terminal SNARE motif of SNAP23
    cd15895
    Location:975
    SNARE_SNAP23N; N-terminal SNARE motif of SNAP23
  2. NM_001177793.1NP_001171264.1  synaptosomal-associated protein 23 isoform b

    See identical proteins and their annotated locations for NP_001171264.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) uses a different splice site in the 5' UTR and lacks an alternate, in-frame, coding exon, compared to variant 1. Variants 2 and 3 encode the same protein (isoform b).
    Source sequence(s)
    AK019162, BC070456
    Consensus CDS
    CCDS16622.1
    UniProtKB/Swiss-Prot
    O09044
    UniProtKB/TrEMBL
    A2AKH4
    Related
    ENSMUSP00000028743, OTTMUSP00000016635, ENSMUST00000028743, OTTMUST00000037103
    Conserved Domains (3) summary
    pfam00835
    Location:86146
    SNAP-25; SNAP-25 family
    cd15884
    Location:148206
    SNARE_SNAP23C; C-terminal SNARE motif of SNAP23
    cd15895
    Location:975
    SNARE_SNAP23N; N-terminal SNARE motif of SNAP23
  3. NM_009222.3NP_033248.1  synaptosomal-associated protein 23 isoform b

    See identical proteins and their annotated locations for NP_033248.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate, in-frame, exon, compared to variant 1. Variants 2 and 3 encode the same protein (isoform b).
    Source sequence(s)
    AK019162
    Consensus CDS
    CCDS16622.1
    UniProtKB/Swiss-Prot
    O09044
    UniProtKB/TrEMBL
    A2AKH4
    Related
    ENSMUSP00000106339, OTTMUSP00000016633, ENSMUST00000110711, OTTMUST00000037101
    Conserved Domains (3) summary
    pfam00835
    Location:86146
    SNAP-25; SNAP-25 family
    cd15884
    Location:148206
    SNARE_SNAP23C; C-terminal SNARE motif of SNAP23
    cd15895
    Location:975
    SNARE_SNAP23N; N-terminal SNARE motif of SNAP23

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000068.7 Reference GRCm38.p3 C57BL/6J

    Range
    120567651..120601255
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006499055.2XP_006499118.1  

    See identical proteins and their annotated locations for XP_006499118.1

    UniProtKB/TrEMBL
    Q9D3L3
    Conserved Domains (3) summary
    pfam00835
    Location:100157
    SNAP-25; SNAP-25 family
    cd15884
    Location:159217
    SNARE_SNAP23C; C-terminal SNARE motif of SNAP23
    cd15895
    Location:975
    SNARE_SNAP23N; N-terminal SNARE motif of SNAP23
  2. XM_006499054.2XP_006499117.1  

    See identical proteins and their annotated locations for XP_006499117.1

    UniProtKB/TrEMBL
    Q9D3L3
    Conserved Domains (3) summary
    pfam00835
    Location:100157
    SNAP-25; SNAP-25 family
    cd15884
    Location:159217
    SNARE_SNAP23C; C-terminal SNARE motif of SNAP23
    cd15895
    Location:975
    SNARE_SNAP23N; N-terminal SNARE motif of SNAP23
  3. XM_006499057.2XP_006499120.1  

    See identical proteins and their annotated locations for XP_006499120.1

    UniProtKB/Swiss-Prot
    O09044
    UniProtKB/TrEMBL
    A2AKH4
    Conserved Domains (3) summary
    pfam00835
    Location:86146
    SNAP-25; SNAP-25 family
    cd15884
    Location:148206
    SNARE_SNAP23C; C-terminal SNARE motif of SNAP23
    cd15895
    Location:975
    SNARE_SNAP23N; N-terminal SNARE motif of SNAP23
  4. XM_006499056.2XP_006499119.1  

    See identical proteins and their annotated locations for XP_006499119.1

    UniProtKB/TrEMBL
    Q9D3L3
    Conserved Domains (3) summary
    pfam00835
    Location:100157
    SNAP-25; SNAP-25 family
    cd15884
    Location:159217
    SNARE_SNAP23C; C-terminal SNARE motif of SNAP23
    cd15895
    Location:975
    SNARE_SNAP23N; N-terminal SNARE motif of SNAP23

Alternate Mm_Celera

Genomic

  1. AC_000024.1 Alternate Mm_Celera

    Range
    121720414..121753492
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)