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Snap91 synaptosomal-associated protein 91 [ Mus musculus (house mouse) ]

Gene ID: 20616, updated on 8-May-2016
Official Symbol
Snap91provided by MGI
Official Full Name
synaptosomal-associated protein 91provided by MGI
Primary source
MGI:MGI:109132
See related
Ensembl:ENSMUSG00000033419 Vega:OTTMUSG00000045050
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
91kDa; AP180; F1-20; mKIAA0656
Orthologs
Location:
9; 9 E3.2
Exon count:
32
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 9 NC_000075.6 (86765923..86880708, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (86659239..86775207, complement)

Chromosome 9 - NC_000075.6Genomic Context describing neighboring genes Neighboring gene malic enzyme 1, NADP(+)-dependent, cytosolic Neighboring gene RIKEN cDNA A330041J22 gene Neighboring gene protease, serine 35 Neighboring gene predicted gene, 39389 Neighboring gene predicted gene, 36539

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
1-phosphatidylinositol binding IDA
Inferred from Direct Assay
more info
PubMed 
clathrin binding IEA
Inferred from Electronic Annotation
more info
 
clathrin heavy chain binding IPI
Inferred from Physical Interaction
more info
PubMed 
phospholipid binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein kinase binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
axonogenesis ISO
Inferred from Sequence Orthology
more info
 
clathrin coat assembly IDA
Inferred from Direct Assay
more info
PubMed 
clathrin coat assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
establishment or maintenance of cell polarity ISO
Inferred from Sequence Orthology
more info
 
neurotransmitter secretion IMP
Inferred from Mutant Phenotype
more info
PubMed 
protein transport IEA
Inferred from Electronic Annotation
more info
 
regulation of clathrin-mediated endocytosis ISO
Inferred from Sequence Orthology
more info
PubMed 
regulation of endocytosis ISO
Inferred from Sequence Orthology
more info
 
regulation of protein transport ISO
Inferred from Sequence Orthology
more info
 
synaptic transmission IMP
Inferred from Mutant Phenotype
more info
PubMed 
transport IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
AP-2 adaptor complex IC
Inferred by Curator
more info
PubMed 
clathrin-coated vesicle IEA
Inferred from Electronic Annotation
more info
 
coated pit IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 
postsynaptic density ISO
Inferred from Sequence Orthology
more info
 
postsynaptic membrane ISO
Inferred from Sequence Orthology
more info
 
presynaptic membrane ISO
Inferred from Sequence Orthology
more info
 
synaptic vesicle ISO
Inferred from Sequence Orthology
more info
 
terminal bouton ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
clathrin coat assembly protein AP180
Names
91 kDa synaptosomal-associated protein
clathrin coat-associated protein AP180
phosphoprotein F1-20
synaptosomal-associated protein, 91 kDa

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001277982.1NP_001264911.1  clathrin coat assembly protein AP180 isoform 3

    See identical proteins and their annotated locations for NP_001264911.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) has an alternate splice site and lacks an in-frame exon in the 3' coding region, compared to variant 1. The resulting isoform (3) is shorter and lacks two segments in the C-terminal region, compared to isoform 1.
    Source sequence(s)
    BC031773, BC052454, CA315349
    UniProtKB/Swiss-Prot
    Q61548
    UniProtKB/TrEMBL
    Q7TT20
    Conserved Domains (1) summary
    cd03564
    Location:24138
    ANTH_AP180_CALM; ANTH domain family; composed of adaptor protein 180 (AP180), clathrin assembly lymphoid myeloid leukemia protein (CALM) and similar proteins. A set of proteins previously designated as harboring an ENTH domain in fact contains a highly similar, yet ...
  2. NM_001277983.1NP_001264912.1  clathrin coat assembly protein AP180 isoform 4

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) lacks four in-frame exons in the coding region, compared to variant 1. The resulting isoform (4) is shorter and lacks four internal segments, compared to isoform 1.
    Source sequence(s)
    BC052454, CA315349
    Consensus CDS
    CCDS72289.1
    UniProtKB/TrEMBL
    E9Q9A3, Q7TT20
    Related
    ENSMUSP00000096096, OTTMUSP00000066085, ENSMUST00000098495, OTTMUST00000118387
    Conserved Domains (1) summary
    cd03564
    Location:24138
    ANTH_AP180_CALM; ANTH domain family; composed of adaptor protein 180 (AP180), clathrin assembly lymphoid myeloid leukemia protein (CALM) and similar proteins. A set of proteins previously designated as harboring an ENTH domain in fact contains a highly similar, yet ...
  3. NM_001277985.1NP_001264914.1  clathrin coat assembly protein AP180 isoform 5

    See identical proteins and their annotated locations for NP_001264914.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) lacks multiple exons in the coding region, compared to variant 1. The The resulting isoform (5) lacks two internal segments and has a shorter and distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AK159570, BC052454, CA315349, CA560936, CN692883
    Consensus CDS
    CCDS72288.1
    UniProtKB/TrEMBL
    Q3TWS4, Q7TT20
    Related
    ENSMUSP00000074095, OTTMUSP00000066086, ENSMUST00000074501, OTTMUST00000118389
    Conserved Domains (1) summary
    cd03564
    Location:24138
    ANTH_AP180_CALM; ANTH domain family; composed of adaptor protein 180 (AP180), clathrin assembly lymphoid myeloid leukemia protein (CALM) and similar proteins. A set of proteins previously designated as harboring an ENTH domain in fact contains a highly similar, yet ...
  4. NM_001277986.1NP_001264915.1  clathrin coat assembly protein AP180 isoform 2

    See identical proteins and their annotated locations for NP_001264915.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) has an alternate splice site in the 3' coding region, compared to variant 1. The resulting isoform (2) lacks an internal segment, compared to isoform 1.
    Source sequence(s)
    BC031773, BC052454, CA315349
    UniProtKB/Swiss-Prot
    Q61548
    UniProtKB/TrEMBL
    Q7TT20
    Conserved Domains (1) summary
    cd03564
    Location:24138
    ANTH_AP180_CALM; ANTH domain family; composed of adaptor protein 180 (AP180), clathrin assembly lymphoid myeloid leukemia protein (CALM) and similar proteins. A set of proteins previously designated as harboring an ENTH domain in fact contains a highly similar, yet ...
  5. NM_013669.2NP_038697.1  clathrin coat assembly protein AP180 isoform 1

    See identical proteins and their annotated locations for NP_038697.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (1).
    Source sequence(s)
    BC052454, CA315349
    UniProtKB/Swiss-Prot
    Q61548
    UniProtKB/TrEMBL
    Q7TT20
    Conserved Domains (1) summary
    cd03564
    Location:24138
    ANTH_AP180_CALM; ANTH domain family; composed of adaptor protein 180 (AP180), clathrin assembly lymphoid myeloid leukemia protein (CALM) and similar proteins. A set of proteins previously designated as harboring an ENTH domain in fact contains a highly similar, yet ...

RNA

  1. NR_102729.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) has an additional internal exon, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon, as used in variant 1, renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
    Source sequence(s)
    BC052454, CA315349

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000075.6 Reference GRCm38.p3 C57BL/6J

    Range
    86765923..86880708 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006510897.1XP_006510960.1  

    Conserved Domains (1) summary
    cd03564
    Location:24138
    ANTH_AP180_CALM; ANTH domain family; composed of adaptor protein 180 (AP180), clathrin assembly lymphoid myeloid leukemia protein (CALM) and similar proteins. A set of proteins previously designated as harboring an ENTH domain in fact contains a highly similar, yet ...
  2. XM_006510894.2XP_006510957.1  

    See identical proteins and their annotated locations for XP_006510957.1

    UniProtKB/Swiss-Prot
    Q61548
    Conserved Domains (1) summary
    cd03564
    Location:24138
    ANTH_AP180_CALM; ANTH domain family; composed of adaptor protein 180 (AP180), clathrin assembly lymphoid myeloid leukemia protein (CALM) and similar proteins. A set of proteins previously designated as harboring an ENTH domain in fact contains a highly similar, yet ...
  3. XM_006510904.2XP_006510967.1  

    Conserved Domains (1) summary
    cd03564
    Location:24138
    ANTH_AP180_CALM; ANTH domain family; composed of adaptor protein 180 (AP180), clathrin assembly lymphoid myeloid leukemia protein (CALM) and similar proteins. A set of proteins previously designated as harboring an ENTH domain in fact contains a highly similar, yet ...
  4. XM_006510895.2XP_006510958.1  

    See identical proteins and their annotated locations for XP_006510958.1

    Related
    ENSMUSP00000074066, ENSMUST00000074468
    Conserved Domains (1) summary
    cd03564
    Location:24138
    ANTH_AP180_CALM; ANTH domain family; composed of adaptor protein 180 (AP180), clathrin assembly lymphoid myeloid leukemia protein (CALM) and similar proteins. A set of proteins previously designated as harboring an ENTH domain in fact contains a highly similar, yet ...
  5. XM_006510903.2XP_006510966.1  

    Conserved Domains (1) summary
    cd03564
    Location:24138
    ANTH_AP180_CALM; ANTH domain family; composed of adaptor protein 180 (AP180), clathrin assembly lymphoid myeloid leukemia protein (CALM) and similar proteins. A set of proteins previously designated as harboring an ENTH domain in fact contains a highly similar, yet ...
  6. XM_006510896.2XP_006510959.1  

    Conserved Domains (1) summary
    cd03564
    Location:24138
    ANTH_AP180_CALM; ANTH domain family; composed of adaptor protein 180 (AP180), clathrin assembly lymphoid myeloid leukemia protein (CALM) and similar proteins. A set of proteins previously designated as harboring an ENTH domain in fact contains a highly similar, yet ...
  7. XM_006510901.2XP_006510964.1  

    Conserved Domains (1) summary
    cd03564
    Location:24138
    ANTH_AP180_CALM; ANTH domain family; composed of adaptor protein 180 (AP180), clathrin assembly lymphoid myeloid leukemia protein (CALM) and similar proteins. A set of proteins previously designated as harboring an ENTH domain in fact contains a highly similar, yet ...
  8. XM_006510902.2XP_006510965.1  

    Conserved Domains (1) summary
    cd03564
    Location:24138
    ANTH_AP180_CALM; ANTH domain family; composed of adaptor protein 180 (AP180), clathrin assembly lymphoid myeloid leukemia protein (CALM) and similar proteins. A set of proteins previously designated as harboring an ENTH domain in fact contains a highly similar, yet ...
  9. XM_006510899.2XP_006510962.1  

    Conserved Domains (1) summary
    cd03564
    Location:24138
    ANTH_AP180_CALM; ANTH domain family; composed of adaptor protein 180 (AP180), clathrin assembly lymphoid myeloid leukemia protein (CALM) and similar proteins. A set of proteins previously designated as harboring an ENTH domain in fact contains a highly similar, yet ...
  10. XM_006510900.2XP_006510963.1  

    See identical proteins and their annotated locations for XP_006510963.1

    UniProtKB/Swiss-Prot
    Q61548
    Related
    ENSMUSP00000046189, ENSMUST00000036347
    Conserved Domains (1) summary
    cd03564
    Location:24138
    ANTH_AP180_CALM; ANTH domain family; composed of adaptor protein 180 (AP180), clathrin assembly lymphoid myeloid leukemia protein (CALM) and similar proteins. A set of proteins previously designated as harboring an ENTH domain in fact contains a highly similar, yet ...
  11. XM_006510898.2XP_006510961.1  

    Conserved Domains (1) summary
    cd03564
    Location:24138
    ANTH_AP180_CALM; ANTH domain family; composed of adaptor protein 180 (AP180), clathrin assembly lymphoid myeloid leukemia protein (CALM) and similar proteins. A set of proteins previously designated as harboring an ENTH domain in fact contains a highly similar, yet ...

Alternate Mm_Celera

Genomic

  1. AC_000031.1 Alternate Mm_Celera

    Range
    83843022..83967649 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)