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Snap25 synaptosomal-associated protein 25 [ Mus musculus (house mouse) ]

Gene ID: 20614, updated on 28-May-2016
Official Symbol
Snap25provided by MGI
Official Full Name
synaptosomal-associated protein 25provided by MGI
Primary source
MGI:MGI:98331
See related
Ensembl:ENSMUSG00000027273 Vega:OTTMUSG00000015556
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
sp; Bdr; SUP; GENA70; SNAP-25
Orthologs
Location:
2 F3; 2 67.56 cM
Exon count:
9
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 2 NC_000068.7 (136713438..136782428)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (136539186..136608164)

Chromosome 2 - NC_000068.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 32746 Neighboring gene predicted gene, 32659 Neighboring gene ankyrin repeat and EF-hand domain containing 1 Neighboring gene 60S ribosomal protein L21 pseudogene Neighboring gene predicted gene, 39943 Neighboring gene McKusick-Kaufman syndrome Neighboring gene SLX4 interacting protein

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
SNAP receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
SNARE binding IDA
Inferred from Direct Assay
more info
PubMed 
SNARE binding ISO
Inferred from Sequence Orthology
more info
PubMed 
calcium-dependent protein binding ISO
Inferred from Sequence Orthology
more info
 
ion channel binding ISO
Inferred from Sequence Orthology
more info
 
myosin binding ISO
Inferred from Sequence Orthology
more info
 
protein N-terminus binding ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein domain specific binding ISO
Inferred from Sequence Orthology
more info
 
syntaxin-1 binding IBA
Inferred from Biological aspect of Ancestor
more info
 
syntaxin-1 binding ISO
Inferred from Sequence Orthology
more info
PubMed 
voltage-gated potassium channel activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
associative learning IMP
Inferred from Mutant Phenotype
more info
PubMed 
calcium ion-regulated exocytosis of neurotransmitter ISO
Inferred from Sequence Orthology
more info
 
endosomal transport ISO
Inferred from Sequence Orthology
more info
 
locomotory behavior IMP
Inferred from Mutant Phenotype
more info
PubMed 
long-term memory ISO
Inferred from Sequence Orthology
more info
 
long-term synaptic potentiation IMP
Inferred from Mutant Phenotype
more info
PubMed 
neurotransmitter secretion IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of hormone secretion ISO
Inferred from Sequence Orthology
more info
 
regulation of establishment of protein localization IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of neuron projection development IGI
Inferred from Genetic Interaction
more info
PubMed 
regulation of neuron projection development ISO
Inferred from Sequence Orthology
more info
 
sleep ISO
Inferred from Sequence Orthology
more info
 
synaptic vesicle fusion to presynaptic active zone membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
synaptic vesicle priming IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
colocalizes_with BLOC-1 complex ISO
Inferred from Sequence Orthology
more info
 
SNARE complex ISO
Inferred from Sequence Orthology
more info
 
actin cytoskeleton ISO
Inferred from Sequence Orthology
more info
 
axon ISO
Inferred from Sequence Orthology
more info
PubMed 
axonal growth cone ISO
Inferred from Sequence Orthology
more info
PubMed 
cell junction IEA
Inferred from Electronic Annotation
more info
 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
cytosol ISO
Inferred from Sequence Orthology
more info
 
endosome ISO
Inferred from Sequence Orthology
more info
 
filopodium ISO
Inferred from Sequence Orthology
more info
 
growth cone ISO
Inferred from Sequence Orthology
more info
 
intracellular organelle ISO
Inferred from Sequence Orthology
more info
 
lamellipodium ISO
Inferred from Sequence Orthology
more info
 
membrane IDA
Inferred from Direct Assay
more info
PubMed 
membrane raft ISO
Inferred from Sequence Orthology
more info
 
myelin sheath IDA
Inferred from Direct Assay
more info
PubMed 
neuron projection IDA
Inferred from Direct Assay
more info
PubMed 
neuron projection ISO
Inferred from Sequence Orthology
more info
 
neuronal cell body ISO
Inferred from Sequence Orthology
more info
 
perinuclear region of cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane ISO
Inferred from Sequence Orthology
more info
 
plasma membrane TAS
Traceable Author Statement
more info
PubMed 
presynaptic membrane IDA
Inferred from Direct Assay
more info
PubMed 
synapse IDA
Inferred from Direct Assay
more info
PubMed 
synaptic vesicle IDA
Inferred from Direct Assay
more info
PubMed 
synaptobrevin 2-SNAP-25-syntaxin-1a complex ISO
Inferred from Sequence Orthology
more info
PubMed 
synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex IDA
Inferred from Direct Assay
more info
PubMed 
synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex ISO
Inferred from Sequence Orthology
more info
PubMed 
synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex ISO
Inferred from Sequence Orthology
more info
 
terminal bouton ISO
Inferred from Sequence Orthology
more info
 
trans-Golgi network IDA
Inferred from Direct Assay
more info
PubMed 
colocalizes_with vesicle ISO
Inferred from Sequence Orthology
more info
 
voltage-gated potassium channel complex ISO
Inferred from Sequence Orthology
more info
 
colocalizes_with voltage-gated potassium channel complex ISO
Inferred from Sequence Orthology
more info
 
Preferred Names
synaptosomal-associated protein 25
Names
blind drunk
super protein
synaptosomal-associated 25 kDa protein
synaptosomal-associated protein, 25 kDa

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001291056.1NP_001277985.1  synaptosomal-associated protein 25 isoform b

    See identical proteins and their annotated locations for NP_001277985.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an in-frame exon but contains a different in-frame exon in the central coding region, compared to variant 1. The encoded isoform (b) is the same length but contains an alternate internal segment, compared to isoform a.
    Source sequence(s)
    AI843805, AL732447, AU080862, BC018249
    Consensus CDS
    CCDS71153.1
    UniProtKB/Swiss-Prot
    P60879
    Related
    ENSMUSP00000105725, OTTMUSP00000016583, ENSMUST00000110098, OTTMUST00000036956
    Conserved Domains (3) summary
    pfam00835
    Location:91141
    SNAP-25; SNAP-25 family
    cd15885
    Location:143201
    SNARE_SNAP25C; C-terminal SNARE motif of SNAP25
    cd15894
    Location:1082
    SNARE_SNAP25N; N-terminal SNARE motif of SNAP25
  2. NM_011428.3NP_035558.1  synaptosomal-associated protein 25 isoform a

    See identical proteins and their annotated locations for NP_035558.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes isoform a.
    Source sequence(s)
    AI843805, AL732447, BC018249, CB232574
    Consensus CDS
    CCDS16793.1
    UniProtKB/Swiss-Prot
    P60879
    Related
    ENSMUSP00000028727, OTTMUSP00000016582, ENSMUST00000028727, OTTMUST00000036955
    Conserved Domains (3) summary
    pfam00835
    Location:91141
    SNAP-25; SNAP-25 family
    cd15885
    Location:143201
    SNARE_SNAP25C; C-terminal SNARE motif of SNAP25
    cd15894
    Location:1082
    SNARE_SNAP25N; N-terminal SNARE motif of SNAP25

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000068.7 Reference GRCm38.p3 C57BL/6J

    Range
    136713438..136782428
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006499053.1XP_006499116.1  

    Conserved Domains (2) summary
    pfam00835
    Location:91136
    SNAP-25; SNAP-25 family
    cd15894
    Location:1082
    SNARE_SNAP25N; N-terminal SNARE motif of SNAP25

Alternate Mm_Celera

Genomic

  1. AC_000024.1 Alternate Mm_Celera

    Range
    137909643..137978489
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)