These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in this
section to the one reported in Genomic regions, transcripts, and products above.
mRNA and Protein(s)
-
NM_001980.3 → NP_001971.2 syntaxin-2 isoform 1
Status: VALIDATED
- Description
- Transcript Variant: This variant (1) represents the shorter transcript and encodes the shorter isoform (1).
- Source sequence(s)
-
AC073912, BC047496, DB474363
- Consensus CDS
-
CCDS9269.1
- UniProtKB/Swiss-Prot
-
P32856
- Related
- ENSP00000261653, OTTHUMP00000238636, ENST00000261653, OTTHUMT00000399454
- Conserved Domains (2) summary
-
- cd00179
Location:29 – 180
Blast Score: 320
- SynN; Syntaxin N-terminus domain; syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane; they are a family of receptors for intracellular transport vesicles; each target membrane may ...
- cd00193
Location:194 – 253
Blast Score: 125
- t_SNARE; Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein (SNAP) REceptor domain; these alpha-helical motifs form twisted and parallel heterotetrameric helix bundles; the core complex contains one helix from a protein that is anchored in ...
-
NM_194356.2 → NP_919337.1 syntaxin-2 isoform 2
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) contains an additional segment in the coding region, compared to variant 1. The resulting isoform (2) contains a longer and distinct C-terminus, compared to isoform 1.
- Source sequence(s)
-
AC073912, BC047496, CN418753, DB474363
- Consensus CDS
-
CCDS9270.1
- UniProtKB/Swiss-Prot
-
P32856
- Related
- ENSP00000376178, OTTHUMP00000238637, ENST00000392373, OTTHUMT00000399455
- Conserved Domains (2) summary
-
- cd00179
Location:29 – 180
Blast Score: 317
- SynN; Syntaxin N-terminus domain; syntaxins are nervous system-specific proteins implicated in the docking of synaptic vesicles with the presynaptic plasma membrane; they are a family of receptors for intracellular transport vesicles; each target membrane may ...
- cd00193
Location:194 – 253
Blast Score: 125
- t_SNARE; Soluble NSF (N-ethylmaleimide-sensitive fusion protein)-Attachment protein (SNAP) REceptor domain; these alpha-helical motifs form twisted and parallel heterotetrameric helix bundles; the core complex contains one helix from a protein that is anchored in ...
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs
for chromosomes and scaffolds (contigs) from both reference and alternate assemblies.
Model RNAs and proteins are also reported here.
Reference GRCh37.p5 Primary Assembly
Genomic
-
NC_000012.11 Reference GRCh37.p5 Primary Assembly
- Range
- 131274145..131323811, complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate HuRef
Genomic
-
AC_000144.1 Alternate HuRef
- Range
- 128256936..128306681, complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)