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    Sec61g SEC61, gamma subunit [ Mus musculus (house mouse) ]

    Gene ID: 20335, updated on 4-May-2013
    Official Symbol
    Sec61gprovided by MGI
    Official Full Name
    SEC61, gamma subunitprovided by MGI
    Primary source
    MGI:1202066
    Locus tag
    RP23-188C13.1
    See related
    Ensembl:ENSMUSG00000078974
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
    Location :
    11 A2; 11
    Sequence :
    Chromosome: 11; NC_000077.6 (16501638..16508484, complement)
    See Sec61g in Epigenomics, MapViewer

    Chromosome 11 - NC_000077.6Genomic Context describing neighboring genes Neighboring gene V-set and transmembrane domain containing 2A Neighboring gene pygopus homolog 2-like Neighboring gene thymoma viral proto-oncogene 2, pseudogene Neighboring gene predicted gene 12663

    Go to nucleotideGraphics FASTA GenBank

    Go to reference sequence details

    Related articles in PubMed

    1. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750.
    2. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693.
    3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073.
    4. The transcriptional landscape of the mammalian genome. Carninci P, et al. Science, 2005 Sep 2. PMID 16141072.
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions What's a GeneRIF?

    Submit: New GeneRIF Correction

    Markers

    Genotypes

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    cellular_component ND
    No biological Data available
    more info
    		  
    Preferred Names
    protein transport protein Sec61 subunit gamma
    Names
    protein transport protein Sec61 subunit gamma

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109971.1 → NP_001103441.1  protein transport protein Sec61 subunit gamma isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) includes an alternate segment in exon 1, compared to variant 1. This causes translation initiation at a downstream AUG and an isoform (2) with a shorter N-terminus compared to isoform 1.
      Source sequence(s)
      AK012393, AK012644, BY468217, CO808059
      Consensus CDS
      CCDS48755.1
      UniProtKB/Swiss-Prot
      P60060
      UniProtKB/TrEMBL
      Q5SWJ8
      Related
      ENSMUSP00000137362, ENSMUST00000178855
      Conserved Domains (1) summary
      cl00481
      Location:12 – 68
      Blast Score: 157
      SecE; SecE/Sec61-gamma subunits of protein translocation complex

    2. NM_001109972.1 → NP_001103442.1  protein transport protein Sec61 subunit gamma isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) includes an alternate segment in exon 1, compared to variant 1. This causes translation initiation at a downstream AUG and an isoform (2) with a shorter N-terminus compared to isoform 1.
      Source sequence(s)
      AK012644, AV456975, CO808059
      Consensus CDS
      CCDS48755.1
      UniProtKB/Swiss-Prot
      P60060
      UniProtKB/TrEMBL
      Q5SWJ8
      Conserved Domains (1) summary
      cl00481
      Location:12 – 68
      Blast Score: 157
      SecE; SecE/Sec61-gamma subunits of protein translocation complex

    3. NM_011343.3 → NP_035473.2  protein transport protein Sec61 subunit gamma isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longer isoform (1).
      Source sequence(s)
      AK012644, CO808059
      Consensus CDS
      CCDS48756.1
      UniProtKB/TrEMBL
      G3UWH0
      UniProtKB/Swiss-Prot
      P60060
      Related
      ENSMUSP00000132348, ENSMUST00000166950
      Conserved Domains (1) summary
      cl00481
      Location:44 – 100
      Blast Score: 165
      SecE; SecE/Sec61-gamma subunits of protein translocation complex

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 103

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p1 C57BL/6J

    Genomic

    1. NC_000077.6 Reference GRCm38.p1 C57BL/6J

      Range
      16501638..16508484, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate Mm_Celera

    Genomic

    1. AC_000033.1 Alternate Mm_Celera

      Range
      16882412..16889258, complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    genomic AAHY01090972.1 (3012..9858) None
    genomic AL603924.18 (111939..118785) None ZRU
    genomic CH466574.1 EDL40660.1 mixed
      EDL40661.1 mixed
      EDL40662.1 mixed
    mRNA AK012393.1 BAB28210.1 C57BL/6J
    mRNA AK012644.1 BAB28376.1 C57BL/6J
    mRNA AK160390.1 BAE35762.1 C57BL/6J
    mRNA AV456975.1 None
    mRNA BC019129.1 None
    mRNA BC019158.1 AAH19158.1
    mRNA BC081456.1 AAH81456.1 C57BL/6
    mRNA BY468217.1 None C57BL/6J
    mRNA CO808059.1 None
    mRNA M88756.1 None C3H/HeJ
    mRNA U11027.1 AAA19431.1 C57BL/6J
    Protein Accession Links
    GenPept Link UniProtKB Link
    P60060.1 GenPept UniProtKB/Swiss-Prot:P60060

    Additional Links

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
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      Supplemental Content

      Table of contents

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      • Order cDNA clone
        Order cDNA clone
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      • BioSystems
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      • CCDS
        Links from Gene to CCDS are established if a gene encodes a protein sequence that is a member of a Consensus CDS (CCDS).
      • Conserved Domains
        Conserved Domain Database Links between Entrez Gene and Conserved Domain Database (CDD) are calculated from the domains annotated by the CDD group on Reference Sequence proteins.
      • dbVar
        Link from Gene to dbVar
      • EST
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        PMC links
      • Full text in PMC_nucleotide
        Full text in PubMedCentral identified from shared sequence links
      • Genome
        Genome records having the gene annotated on corresponding genomic reference sequence.
      • GEO Profiles
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      • HomoloGene
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      • Map Viewer
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      • Nucleotide
        Link to related Nucleotide entry
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        Related Probe entry
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        Link to related protein entry
      • PubChem Compound
        PubChem Compounds
      • PubChem Substance
        PubChem Substances
      • PubMed
        Links between Gene and PubMed are the result of the following: 1. Manual curation within NCBI. Part of the process of generating a REVIEWED RefSeq is an analysis of the current literature. Papers that are seminal in defining the gene, its sequence, and its function are added to the record at that time. Alert users point out gaps or errors in papers associated with a Gene record. These messages are reviewed and implemented as required. 2. Integration of information from other public databases. Gene integrates gene-citation from resources external to NCBI such as model organism-specific databases, Gene Ontology (GO), groups curating interactions, and sequence databases. The assumption in using these source is that they report citations specific to a gene in a known species. Gene does not process citations from OMIM automatically, because many of citations in OMIM refer to studies of genes in species other than human.
      • PubMed(nucleotide/PMC)
        Citations in PubMed identified from shared sequence and PMC links.
      • RefSeq Proteins
        Link to Protein RefSeqs
      • RefSeq RNAs
        Link to Nucleotide RefSeq RNAs
      • SNP
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        SNPs linked from GeneView
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        Gene Genotype Report
      • Taxonomy
        Link to related taxonomy entry
      • UniGene
        Links are provided between Gene and UniGene when both databases calculate links to the same mRNA record (gi).
      • UniSTS
        Related UniSTS records

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