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Nptn neuroplastin [ Mus musculus (house mouse) ]

Gene ID: 20320, updated on 15-May-2016
Official Symbol
Nptnprovided by MGI
Official Full Name
neuroplastinprovided by MGI
Primary source
MGI:MGI:108077
See related
Ensembl:ENSMUSG00000032336 Vega:OTTMUSG00000042067
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
SDR-1; Sdfr1; AW554172
Orthologs
Location:
9; 9 B
Exon count:
11
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 9 NC_000075.6 (58582240..58652879)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (58430047..58500686)

Chromosome 9 - NC_000075.6Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 6030419C18 gene Neighboring gene predicted gene, 40521 Neighboring gene CD276 antigen Neighboring gene REC114 meiotic recombination protein Neighboring gene predicted gene, 21183 Neighboring gene hyperpolarization-activated, cyclic nucleotide-gated K+ 4

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
transmembrane receptor protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
cell adhesion IEA
Inferred from Electronic Annotation
more info
 
excitatory synapse assembly IMP
Inferred from Mutant Phenotype
more info
PubMed 
modulation of synaptic transmission IMP
Inferred from Mutant Phenotype
more info
PubMed 
nervous system development IEA
Inferred from Electronic Annotation
more info
 
regulation of receptor localization to synapse IMP
Inferred from Mutant Phenotype
more info
PubMed 
synapse organization IMP
Inferred from Mutant Phenotype
more info
PubMed 
transmembrane receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
dendrite IDA
Inferred from Direct Assay
more info
PubMed 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane IEA
Inferred from Electronic Annotation
more info
 
Preferred Names
neuroplastin
Names
stromal cell derived factor receptor 1

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001293673.1NP_001280602.1  neuroplastin isoform 2 precursor

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1. The encoded protein (isoform 2) is shorter, compared to isoform 1.
    Source sequence(s)
    AA790392, AK075610, BY266099, CT030640
    Consensus CDS
    CCDS81009.1
    UniProtKB/Swiss-Prot
    P97300
    Related
    ENSMUSP00000135541, OTTMUSP00000061523, ENSMUST00000176557, OTTMUST00000110328
    Conserved Domains (3) summary
    smart00410
    Location:128216
    IG_like; Immunoglobulin like
    pfam13927
    Location:31104
    Ig_3; Immunoglobulin domain
    cl11960
    Location:119216
    Ig; Immunoglobulin domain
  2. NM_009145.2NP_033171.2  neuroplastin isoform 1 precursor

    See identical proteins and their annotated locations for NP_033171.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    CT030640
    Consensus CDS
    CCDS23245.1
    UniProtKB/Swiss-Prot
    P97300
    Related
    ENSMUSP00000082793, OTTMUSP00000061515, ENSMUST00000085651, OTTMUST00000110316
    Conserved Domains (3) summary
    smart00410
    Location:128216
    IG_like; Immunoglobulin like
    pfam13927
    Location:31104
    Ig_3; Immunoglobulin domain
    cl11960
    Location:119216
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000075.6 Reference GRCm38.p3 C57BL/6J

    Range
    58582240..58652879
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006510883.1XP_006510946.1  

    See identical proteins and their annotated locations for XP_006510946.1

    UniProtKB/Swiss-Prot
    P97300
    Conserved Domains (5) summary
    cd00096
    Location:49122
    Ig; Immunoglobulin domain
    smart00408
    Location:45120
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:244332
    IG_like; Immunoglobulin like
    pfam13927
    Location:147220
    Ig_3; Immunoglobulin domain
    cl11960
    Location:235332
    Ig; Immunoglobulin domain
  2. XM_006510882.1XP_006510945.1  

    See identical proteins and their annotated locations for XP_006510945.1

    UniProtKB/Swiss-Prot
    P97300
    Related
    ENSMUSP00000135199, OTTMUSP00000061517, ENSMUST00000177292, OTTMUST00000110319
    Conserved Domains (5) summary
    cd00096
    Location:49122
    Ig; Immunoglobulin domain
    smart00408
    Location:45120
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:244332
    IG_like; Immunoglobulin like
    pfam13927
    Location:147220
    Ig_3; Immunoglobulin domain
    cl11960
    Location:235332
    Ig; Immunoglobulin domain
  3. XM_006510884.1XP_006510947.1  

    Conserved Domains (5) summary
    cd00096
    Location:49122
    Ig; Immunoglobulin domain
    smart00408
    Location:45120
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:244332
    IG_like; Immunoglobulin like
    pfam13927
    Location:147220
    Ig_3; Immunoglobulin domain
    cl11960
    Location:235332
    Ig; Immunoglobulin domain
  4. XM_006510886.2XP_006510949.1  

    Conserved Domains (5) summary
    cd00096
    Location:49122
    Ig; Immunoglobulin domain
    smart00408
    Location:45120
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:244332
    IG_like; Immunoglobulin like
    pfam13927
    Location:147220
    Ig_3; Immunoglobulin domain
    cl11960
    Location:235332
    Ig; Immunoglobulin domain
  5. XM_006510885.2XP_006510948.1  

    Conserved Domains (5) summary
    cd00096
    Location:49122
    Ig; Immunoglobulin domain
    smart00408
    Location:45120
    IGc2; Immunoglobulin C-2 Type
    smart00410
    Location:244332
    IG_like; Immunoglobulin like
    pfam13927
    Location:147220
    Ig_3; Immunoglobulin domain
    cl11960
    Location:235332
    Ig; Immunoglobulin domain

Alternate Mm_Celera

Genomic

  1. AC_000031.1 Alternate Mm_Celera

    Range
    55815258..55885738
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)