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Cxcl15 chemokine (C-X-C motif) ligand 15 [ Mus musculus (house mouse) ]

Gene ID: 20309, updated on 8-May-2016
Official Symbol
Cxcl15provided by MGI
Official Full Name
chemokine (C-X-C motif) ligand 15provided by MGI
Primary source
MGI:MGI:1339941
See related
Ensembl:ENSMUSG00000029375 Vega:OTTMUSG00000055507
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Il8; weche; Scyb15; lungkine
Location:
5 E1; 5 44.78 cM
Exon count:
4
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 5 NC_000071.6 (90794534..90803067)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 5 NC_000071.5 (91223560..91232093)

Chromosome 5 - NC_000071.6Genomic Context describing neighboring genes Neighboring gene platelet factor 4 Neighboring gene chemokine (C-X-C motif) ligand 3 Neighboring gene chemokine (C-X-C motif) ligand 1 Neighboring gene chemokine (C-X-C motif) ligand 2

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

  • Chemokine signaling pathway, organism-specific biosystem (from KEGG)
    Chemokine signaling pathway, organism-specific biosystemInflammatory immune response requires the recruitment of leukocytes to the site of inflammation upon foreign insult. Chemokines are small chemoattractant peptides that provide directional cues for th...
  • Chemokine signaling pathway, organism-specific biosystem (from WikiPathways)
    Chemokine signaling pathway, organism-specific biosystemInflammatory immune response requires the recruitment of leukocytes to the site of inflammation upon foreign insult. Chemokines are small chemoattractant peptides that provide directional cues for th...
  • Chemokine signaling pathway, conserved biosystem (from KEGG)
    Chemokine signaling pathway, conserved biosystemInflammatory immune response requires the recruitment of leukocytes to the site of inflammation upon foreign insult. Chemokines are small chemoattractant peptides that provide directional cues for th...
  • Cytokine-cytokine receptor interaction, organism-specific biosystem (from KEGG)
    Cytokine-cytokine receptor interaction, organism-specific biosystemCytokines are soluble extracellular proteins or glycoproteins that are crucial intercellular regulators and mobilizers of cells engaged in innate as well as adaptive inflammatory host defenses, cell ...
  • Cytokine-cytokine receptor interaction, conserved biosystem (from KEGG)
    Cytokine-cytokine receptor interaction, conserved biosystemCytokines are soluble extracellular proteins or glycoproteins that are crucial intercellular regulators and mobilizers of cells engaged in innate as well as adaptive inflammatory host defenses, cell ...

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
CXCR chemokine receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
 
chemokine activity IDA
Inferred from Direct Assay
more info
PubMed 
cytokine activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
G-protein coupled receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
chemokine-mediated signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
chemotaxis IDA
Inferred from Direct Assay
more info
PubMed 
hemopoiesis IDA
Inferred from Direct Assay
more info
PubMed 
immune response IBA
Inferred from Biological aspect of Ancestor
more info
 
inflammatory response IDA
Inferred from Direct Assay
more info
PubMed 
neutrophil chemotaxis IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of neutrophil chemotaxis IBA
Inferred from Biological aspect of Ancestor
more info
 
regulation of cell proliferation IBA
Inferred from Biological aspect of Ancestor
more info
 
response to lipopolysaccharide IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
extracellular region IDA
Inferred from Direct Assay
more info
PubMed 
extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
 
Preferred Names
C-X-C motif chemokine 15
Names
interleukin 8
small inducible cytokine subfamily B, member 15
small-inducible cytokine B15

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_011339.2NP_035469.1  C-X-C motif chemokine 15 precursor

    See identical proteins and their annotated locations for NP_035469.1

    Status: VALIDATED

    Source sequence(s)
    AK142955
    Consensus CDS
    CCDS19418.1
    UniProtKB/Swiss-Prot
    Q9WVL7
    Related
    ENSMUSP00000031322, OTTMUSP00000072363, ENSMUST00000031322, OTTMUST00000137385
    Conserved Domains (1) summary
    cd00273
    Location:2790
    Chemokine_CXC; Chemokine_CXC: 1 of 4 subgroup designations based on the arrangement of the two N-terminal cysteine residues; includes a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity; many members ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000071.6 Reference GRCm38.p3 C57BL/6J

    Range
    90794534..90803067
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCm38.p3 129S1/SvImJ

Genomic

  1. NT_109599.1 Reference GRCm38.p3 129S1/SvImJ

    Range
    23698..32212 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000027.1 Alternate Mm_Celera

    Range
    88946158..88954669
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)