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Ccl22 chemokine (C-C motif) ligand 22 [ Mus musculus (house mouse) ]

Gene ID: 20299, updated on 28-May-2016
Official Symbol
Ccl22provided by MGI
Official Full Name
chemokine (C-C motif) ligand 22provided by MGI
Primary source
MGI:MGI:1306779
See related
Ensembl:ENSMUSG00000031779 Vega:OTTMUSG00000016635
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
MDC; DCBCK; ABCD-1; Scya22
Orthologs
Location:
8; 8 C5
Exon count:
3
Annotation release Status Assembly Chr Location
105 current GRCm38.p3 (GCF_000001635.23) 8 NC_000074.6 (94745684..94751388)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (97269584..97275288)

Chromosome 8 - NC_000074.6Genomic Context describing neighboring genes Neighboring gene nuclear encoded tRNA leucine 5 (anticodon CAG) Neighboring gene nuclear encoded tRNA leucine 4 (anticodon CAG) Neighboring gene guanine nucleotide binding protein (G protein), beta 1, pseudogene 3 Neighboring gene chemokine (C-X3-C motif) ligand 1

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
CCR chemokine receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
 
chemokine activity IBA
Inferred from Biological aspect of Ancestor
more info
 
cytokine activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
G-protein coupled receptor signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
cell chemotaxis IEA
Inferred from Electronic Annotation
more info
 
cellular response to interferon-gamma IBA
Inferred from Biological aspect of Ancestor
more info
 
cellular response to interleukin-1 IBA
Inferred from Biological aspect of Ancestor
more info
 
cellular response to tumor necrosis factor IBA
Inferred from Biological aspect of Ancestor
more info
 
chemokine-mediated signaling pathway IBA
Inferred from Biological aspect of Ancestor
more info
 
chemotaxis IEA
Inferred from Electronic Annotation
more info
 
immune response IEA
Inferred from Electronic Annotation
more info
 
inflammatory response IBA
Inferred from Biological aspect of Ancestor
more info
 
lymphocyte chemotaxis IBA
Inferred from Biological aspect of Ancestor
more info
 
monocyte chemotaxis IBA
Inferred from Biological aspect of Ancestor
more info
 
neutrophil chemotaxis IBA
Inferred from Biological aspect of Ancestor
more info
 
positive regulation of ERK1 and ERK2 cascade IBA
Inferred from Biological aspect of Ancestor
more info
 
positive regulation of GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
extracellular region IEA
Inferred from Electronic Annotation
more info
 
extracellular space IDA
Inferred from Direct Assay
more info
PubMed 
Preferred Names
C-C motif chemokine 22
Names
CC chemokine ABCD-1
SMALL INDUCIBLE CYTOKINE A22 PRECURSOR (CC CHEMOKINE ABCD-1) (ACTIVATED B AND DENDRITIC CELL-DERIVED)
activated B and dendritic cell-derived
dendritic cell and B cell derived chemokine
small inducible cytokine subfamily A, member 22
small inducible cytokine subfamily A22
small-inducible cytokine A22

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_009137.2NP_033163.1  C-C motif chemokine 22 precursor

    See identical proteins and their annotated locations for NP_033163.1

    Status: VALIDATED

    Source sequence(s)
    AK155764, BF661256, BY198556
    Consensus CDS
    CCDS40441.1
    UniProtKB/Swiss-Prot
    O88430
    UniProtKB/TrEMBL
    Q546S6
    Related
    ENSMUSP00000034231, OTTMUSP00000017971, ENSMUST00000034231, OTTMUST00000040245
    Conserved Domains (1) summary
    cd00272
    Location:3692
    Chemokine_CC; Chemokine_CC: 1 of 4 subgroup designations based on the arrangement of the two N-terminal cysteine residues; includes a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity; some members (e.g. ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 105 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p3 C57BL/6J

Genomic

  1. NC_000074.6 Reference GRCm38.p3 C57BL/6J

    Range
    94745684..94751388
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate Mm_Celera

Genomic

  1. AC_000030.1 Alternate Mm_Celera

    Range
    99073978..99079588
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)